ZA201704876B - Substituted nucleosides, nucleotides and analogs thereof - Google Patents

Substituted nucleosides, nucleotides and analogs thereof

Info

Publication number
ZA201704876B
ZA201704876B ZA2017/04876A ZA201704876A ZA201704876B ZA 201704876 B ZA201704876 B ZA 201704876B ZA 2017/04876 A ZA2017/04876 A ZA 2017/04876A ZA 201704876 A ZA201704876 A ZA 201704876A ZA 201704876 B ZA201704876 B ZA 201704876B
Authority
ZA
South Africa
Prior art keywords
nucleotides
analogs
substituted nucleosides
nucleosides
substituted
Prior art date
Application number
ZA2017/04876A
Other languages
English (en)
Inventor
Guangyi Wang
David Bernard Smith
Leonid Beigelman
Christian Andreas Jekle
Original Assignee
Alios Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alios Biopharma Inc filed Critical Alios Biopharma Inc
Publication of ZA201704876B publication Critical patent/ZA201704876B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA2017/04876A 2014-12-19 2017-07-18 Substituted nucleosides, nucleotides and analogs thereof ZA201704876B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462094418P 2014-12-19 2014-12-19
PCT/US2015/066193 WO2016100569A1 (en) 2014-12-19 2015-12-16 Substituted nucleosides, nucleotides and analogs thereof

Publications (1)

Publication Number Publication Date
ZA201704876B true ZA201704876B (en) 2020-01-29

Family

ID=56127561

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2017/04876A ZA201704876B (en) 2014-12-19 2017-07-18 Substituted nucleosides, nucleotides and analogs thereof

Country Status (12)

Country Link
US (2) US9890188B2 (OSRAM)
EP (1) EP3233879A4 (OSRAM)
JP (1) JP2017538722A (OSRAM)
CN (1) CN107250145A (OSRAM)
AU (1) AU2015364630A1 (OSRAM)
CA (1) CA2970936A1 (OSRAM)
HK (1) HK1245800A1 (OSRAM)
MA (1) MA41213A (OSRAM)
MX (1) MX2017008184A (OSRAM)
TW (1) TW201625658A (OSRAM)
WO (1) WO2016100569A1 (OSRAM)
ZA (1) ZA201704876B (OSRAM)

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BR112023026356A2 (pt) 2021-06-17 2024-03-05 Atea Pharmaceuticals Inc Método para tratar vírus da hepatite c ou uma condição resultante de uma infecção por hepatite c, combinação, uso da combinação, composição farmacêutica, e, kit para o tratamento de vírus da hepatite c
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CN116554249B (zh) * 2022-01-28 2025-03-18 北京恩泰伟医药科技有限公司 抗病毒化合物及其用途
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Also Published As

Publication number Publication date
MX2017008184A (es) 2018-03-06
TW201625658A (zh) 2016-07-16
CN107250145A (zh) 2017-10-13
AU2015364630A1 (en) 2017-07-06
CA2970936A1 (en) 2016-06-23
EP3233879A4 (en) 2018-09-19
JP2017538722A (ja) 2017-12-28
WO2016100569A1 (en) 2016-06-23
EP3233879A1 (en) 2017-10-25
US9890188B2 (en) 2018-02-13
US20180155384A1 (en) 2018-06-07
HK1245800A1 (zh) 2018-08-31
US20160176910A1 (en) 2016-06-23
MA41213A (fr) 2017-10-24

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