HK1245800A1 - 被取代的核苷、核苷酸及其类似物 - Google Patents

被取代的核苷、核苷酸及其类似物 Download PDF

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Publication number
HK1245800A1
HK1245800A1 HK18105072.0A HK18105072A HK1245800A1 HK 1245800 A1 HK1245800 A1 HK 1245800A1 HK 18105072 A HK18105072 A HK 18105072A HK 1245800 A1 HK1245800 A1 HK 1245800A1
Authority
HK
Hong Kong
Prior art keywords
nucleotides
analogs
substituted nucleosides
nucleosides
methods
Prior art date
Application number
HK18105072.0A
Other languages
English (en)
Chinese (zh)
Inventor
Guangyi Wang
David Bernard Smith
Leonid Beigelman
Christian Andreas JEKLE
Original Assignee
Alios Biopharma, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alios Biopharma, Inc. filed Critical Alios Biopharma, Inc.
Publication of HK1245800A1 publication Critical patent/HK1245800A1/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
HK18105072.0A 2014-12-19 2015-12-16 被取代的核苷、核苷酸及其类似物 HK1245800A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462094418P 2014-12-19 2014-12-19
US201462094418P 2014-12-19
PCT/US2015/066193 WO2016100569A1 (en) 2014-12-19 2015-12-16 Substituted nucleosides, nucleotides and analogs thereof

Publications (1)

Publication Number Publication Date
HK1245800A1 true HK1245800A1 (zh) 2018-08-31

Family

ID=56127561

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18105072.0A HK1245800A1 (zh) 2014-12-19 2015-12-16 被取代的核苷、核苷酸及其类似物

Country Status (12)

Country Link
US (2) US9890188B2 (OSRAM)
EP (1) EP3233879A4 (OSRAM)
JP (1) JP2017538722A (OSRAM)
CN (1) CN107250145A (OSRAM)
AU (1) AU2015364630A1 (OSRAM)
CA (1) CA2970936A1 (OSRAM)
HK (1) HK1245800A1 (OSRAM)
MA (1) MA41213A (OSRAM)
MX (1) MX2017008184A (OSRAM)
TW (1) TW201625658A (OSRAM)
WO (1) WO2016100569A1 (OSRAM)
ZA (1) ZA201704876B (OSRAM)

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CN115135383B (zh) 2020-02-18 2024-06-11 吉利德科学公司 抗病毒化合物
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JP7688152B2 (ja) 2021-04-16 2025-06-03 ギリアード サイエンシーズ， インコーポレイテッド アミドを使用してカルバヌクレオシドを調製する方法
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KR20240049311A (ko) 2021-08-18 2024-04-16 길리애드 사이언시즈, 인코포레이티드 인지질 화합물 및 이의 제조 및 사용 방법
WO2023073239A1 (en) 2021-11-01 2023-05-04 Immunic Ag Medical use of n4-hydroxy citicoline compounds
CN116554249B (zh) * 2022-01-28 2025-03-18 北京恩泰伟医药科技有限公司 抗病毒化合物及其用途
CN114288313B (zh) * 2022-02-18 2023-07-04 常晓宇 嘧啶核苷类药物在制备预防或治疗冠状病毒感染性疾病药物中的用途
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Also Published As

Publication number Publication date
CN107250145A (zh) 2017-10-13
MA41213A (fr) 2017-10-24
US9890188B2 (en) 2018-02-13
MX2017008184A (es) 2018-03-06
TW201625658A (zh) 2016-07-16
WO2016100569A1 (en) 2016-06-23
JP2017538722A (ja) 2017-12-28
ZA201704876B (en) 2020-01-29
EP3233879A4 (en) 2018-09-19
CA2970936A1 (en) 2016-06-23
US20160176910A1 (en) 2016-06-23
AU2015364630A1 (en) 2017-07-06
EP3233879A1 (en) 2017-10-25
US20180155384A1 (en) 2018-06-07

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