MA40403A - Méthodes de traitement de paramyxovirus - Google Patents

Méthodes de traitement de paramyxovirus

Info

Publication number
MA40403A
MA40403A MA040403A MA40403A MA40403A MA 40403 A MA40403 A MA 40403A MA 040403 A MA040403 A MA 040403A MA 40403 A MA40403 A MA 40403A MA 40403 A MA40403 A MA 40403A
Authority
MA
Morocco
Prior art keywords
treating
methods
paramyxoviruses
methylpropanoate
cytidine
Prior art date
Application number
MA040403A
Other languages
English (en)
Inventor
Lawrence M Blatt
Sushmita Mukherjee Chanda
John Fry
Qingling Zhang
Original Assignee
Alios Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alios Biopharma Inc filed Critical Alios Biopharma Inc
Publication of MA40403A publication Critical patent/MA40403A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Abstract

La présente invention concerne des procédés pour l'amélioration et/ou le traitement d'une infection à paramyxovirus, ou l'inhibition de la réplication d'un paramyxovirus, par l'utilisation de 3',5'-(2-méthylpropanoate-4'-c-(chlorométhyl)-2'-désoxy-2'-fluoro-cytidine (composé a)), le composé (a) ou son sel pharmaceutiquement acceptable pouvant fournir 4'-c-chlorométhyl-2'-désoxy-2'-fluoro-5'- (tétrahydrogène triphosphate)-cytidine ou son sel pharmaceutiquement acceptable (composé (b)).
MA040403A 2014-07-22 2015-07-20 Méthodes de traitement de paramyxovirus MA40403A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462027719P 2014-07-22 2014-07-22

Publications (1)

Publication Number Publication Date
MA40403A true MA40403A (fr) 2017-05-31

Family

ID=55163588

Family Applications (1)

Application Number Title Priority Date Filing Date
MA040403A MA40403A (fr) 2014-07-22 2015-07-20 Méthodes de traitement de paramyxovirus

Country Status (13)

Country Link
US (1) US20160022724A1 (fr)
EP (1) EP3171878A4 (fr)
JP (1) JP2017525681A (fr)
KR (1) KR20170031231A (fr)
AU (1) AU2015294343A1 (fr)
BR (1) BR112017001162A2 (fr)
CA (1) CA2955604A1 (fr)
CL (1) CL2017000156A1 (fr)
MA (1) MA40403A (fr)
MX (1) MX2017000983A (fr)
RU (1) RU2017105470A (fr)
TW (1) TW201609104A (fr)
WO (1) WO2016014398A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013096680A1 (fr) 2011-12-22 2013-06-27 Alios Biopharma, Inc. Analogues de nucléotide phosphorothioate substitués
ES2702060T3 (es) 2011-12-22 2019-02-27 Alios Biopharma Inc Nucleósidos sustituidos, nucleótidos y sus análogos
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
CN104321333A (zh) 2012-03-21 2015-01-28 沃泰克斯药物股份有限公司 硫代氨基磷酸酯核苷酸前药的固体形式
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
KR102168621B1 (ko) 2012-12-21 2020-10-22 얀센 바이오파마, 인코퍼레이트. 치환된 뉴클레오사이드, 뉴클레오타이드 및 그것의 유사체
AU2013361193B2 (en) 2012-12-21 2018-05-24 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
WO2014165704A1 (fr) 2013-04-05 2014-10-09 Vertex Pharmaceuticals, Inc. Traitement contre une infection par le virus de l'hépatite c utilisant une combinaison de composés
ES2952714T3 (es) 2013-06-26 2023-11-03 Janssen Pharmaceuticals Inc Nucleósidos sustituidos, nucleótidos y análogos de los mismos
UA118760C2 (uk) 2013-06-26 2019-03-11 Аліос Біофарма, Інк. Заміщені нуклеозиди, нуклеотиди та їх аналоги
WO2015054465A1 (fr) 2013-10-11 2015-04-16 Alios Biopharma, Inc. Nucléosides substitués, nucléotides substitués et analogues de ceux-ci
AP2016009653A0 (en) 2014-06-24 2016-12-31 Alios Biopharma Inc Substituted nucleosides, nucleotides and analogs thereof
EA201692535A1 (ru) 2014-06-24 2017-05-31 Элиос Биофарма, Инк. Замещенные нуклеозиды, нуклеотиды и их аналоги
US20160045528A1 (en) * 2014-08-05 2016-02-18 Alios Biopharma, Inc. Combination therapy for treating a paramyxovirus
US9908914B2 (en) 2014-10-28 2018-03-06 Alios Biopharma, Inc. Methods of preparing substituted nucleoside analogs
MA41213A (fr) 2014-12-19 2017-10-24 Alios Biopharma Inc Nucléosides substitués, nucléotides et analogues de ceux-ci
MA41441A (fr) 2014-12-19 2017-12-12 Alios Biopharma Inc Nucléosides substitués, nucléotides et analogues de ceux-ci
EP3268368A4 (fr) 2015-03-11 2018-11-14 Alios Biopharma, Inc. Composés d'aza-pyridone et leurs utilisations
WO2018081449A1 (fr) * 2016-10-27 2018-05-03 Alios Biopharma, Inc. Méthode pour le traitement d'une infection par le virus respiratoire syncytial
WO2018222774A1 (fr) * 2017-05-30 2018-12-06 Alios Biopharma, Inc. Méthodes de traitement des pneumovirus
CN113462656B (zh) * 2021-03-24 2022-09-30 兰州生物制品研究所有限责任公司 一种人三型副流感病毒冷适应温度敏感株及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA926440B (en) * 1991-08-26 1993-06-07 Scripps Research Inst Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus.
JPH0859508A (ja) * 1994-08-16 1996-03-05 Teijin Ltd サイトメガロウイルス網膜炎予防または治療剤
MX2012015292A (es) * 2010-06-24 2013-05-30 Gilead Sciences Inc Pirazolo[1, 5]pirimidinas en la forma de agentes antivirales.
ES2702060T3 (es) * 2011-12-22 2019-02-27 Alios Biopharma Inc Nucleósidos sustituidos, nucleótidos y sus análogos
MX361460B (es) * 2012-03-21 2018-12-06 Alios Biopharma Inc Nucleosidos sustituidos, nucleotidos y analogos de los mismos.

Also Published As

Publication number Publication date
TW201609104A (zh) 2016-03-16
CA2955604A1 (fr) 2016-01-28
US20160022724A1 (en) 2016-01-28
CL2017000156A1 (es) 2017-11-03
JP2017525681A (ja) 2017-09-07
BR112017001162A2 (pt) 2017-11-14
KR20170031231A (ko) 2017-03-20
WO2016014398A1 (fr) 2016-01-28
RU2017105470A3 (fr) 2019-02-28
MX2017000983A (es) 2017-09-01
RU2017105470A (ru) 2018-08-22
AU2015294343A1 (en) 2017-02-02
EP3171878A1 (fr) 2017-05-31
EP3171878A4 (fr) 2018-03-14

Similar Documents

Publication Publication Date Title
MA40403A (fr) Méthodes de traitement de paramyxovirus
SG10201901010PA (en) Combination therapy for treating a paramyxovirus
IL276883A (en) "Compositions, devices, systems, kits and methods for treating skin conditions"
WO2016044556A3 (fr) Inhibiteurs d'arginine méthyltransférase et leurs utilisations
PH12015501588B1 (en) Compounds and methods for treating bacterial infections
EP3258868A4 (fr) Dispositifs, systèmes, et procédés de fixation osseuse semi-rigide
BR112017026061A2 (pt) composto, uso de um composto, e, método de tratamento de uma infecção viral
EP3212658A4 (fr) Analogues de 2',2'-dihalo-nucléosides utilisables en vue du traitement d'infections par des virus de la famille des flaviviridae et du cancer
PH12016501751A1 (en) Pyridazine derivatives for use in the prevention or treatment of an ataxic disorder
MX2021010886A (es) Uso de medicamentos para disminuir la evolucion de la enfermedad de parkinson.
MX2017013047A (es) Tratamiento de dolor.
MX2018005987A (es) Compuestos heterociclicos para el tratamiento de enfermedades.
NZ732704A (en) Quinoline carboxamides for use in the treatment of leukemia
HUE043553T2 (hu) Spiroindolin vegyületek a légúti óriás sejtes vírusfertõzés (RSV) kezeléséhez és megelõzéséhez
MX2020005707A (es) Profarmacos de creatina, composiciones y metodos de uso de estos.
HK1251476A1 (zh) 用於治療癌症的氨基硫羥酸酯化合物或其藥學上可接受的鹽
EP3574089A4 (fr) Agent antiviral et méthode de traitement d'une infection virale
AU2016234411B2 (en) Respiratory infection treating agent
EP3253312A4 (fr) Plaques osseuses, systèmes et procédés d'utilisation
MX2019005504A (es) Potenciadores de bmp.
MY186775A (en) Antibacterial compositions and methods
MX2018012587A (es) (+)-azasetron para uso en el tratamiento de trastornos del oido.
SG10201903630UA (en) Iminosugars useful for the treatment of viral diseases
MX2018002193A (es) Metodo de uso de quinoxalinilo-piperazinamida.
BR112017004947A2 (pt) composto ou sal farmaceuticamente aceitável, uso de um composto ou sal farmaceuticamente aceitável, e, método de tratamento de mieloma múltiplo.