MX2017000983A - Metodos para tratar el paramixovirus. - Google Patents

Metodos para tratar el paramixovirus.

Info

Publication number
MX2017000983A
MX2017000983A MX2017000983A MX2017000983A MX2017000983A MX 2017000983 A MX2017000983 A MX 2017000983A MX 2017000983 A MX2017000983 A MX 2017000983A MX 2017000983 A MX2017000983 A MX 2017000983A MX 2017000983 A MX2017000983 A MX 2017000983A
Authority
MX
Mexico
Prior art keywords
treating
methods
paramyxoviruses
compound
pharmaceutically acceptable
Prior art date
Application number
MX2017000983A
Other languages
English (en)
Inventor
Lawrence M Blatt
Mukjerjee Chanda Sushmita
Zhang Qingling
Fry John
Original Assignee
Alios Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alios Biopharma Inc filed Critical Alios Biopharma Inc
Publication of MX2017000983A publication Critical patent/MX2017000983A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Abstract

En la presente invención se describen métodos para tratar y/o mejorar una infección por paramixovirus que incluye el uso de 3´,5´-(2-metilpropanoato)-4´-C-(clorometil)-2´-desoxi-2´-fluoro-c itidina, o una sal farmacéuticamente aceptable de este, (Compuesto (A)), en donde el Compuesto (A), o una sal farmacéuticamente aceptable de este, puede proporcionar 4´-C-clorometil-2´-desoxi-2´-fluoro-5´-(tetrahidrógeno trifosfato) citidina, o una sal farmacéuticamente aceptable de este (Compuesto (B)).
MX2017000983A 2014-07-22 2015-07-20 Metodos para tratar el paramixovirus. MX2017000983A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462027719P 2014-07-22 2014-07-22
PCT/US2015/041111 WO2016014398A1 (en) 2014-07-22 2015-07-20 Methods for treating paramyxoviruses

Publications (1)

Publication Number Publication Date
MX2017000983A true MX2017000983A (es) 2017-09-01

Family

ID=55163588

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017000983A MX2017000983A (es) 2014-07-22 2015-07-20 Metodos para tratar el paramixovirus.

Country Status (13)

Country Link
US (1) US20160022724A1 (es)
EP (1) EP3171878A4 (es)
JP (1) JP2017525681A (es)
KR (1) KR20170031231A (es)
AU (1) AU2015294343A1 (es)
BR (1) BR112017001162A2 (es)
CA (1) CA2955604A1 (es)
CL (1) CL2017000156A1 (es)
MA (1) MA40403A (es)
MX (1) MX2017000983A (es)
RU (1) RU2017105470A (es)
TW (1) TW201609104A (es)
WO (1) WO2016014398A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013096679A1 (en) 2011-12-22 2013-06-27 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
AU2012358804B2 (en) 2011-12-22 2018-04-19 Alios Biopharma, Inc. Substituted phosphorothioate nucleotide analogs
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
NZ631601A (en) 2012-03-21 2016-06-24 Alios Biopharma Inc Solid forms of a thiophosphoramidate nucleotide prodrug
WO2014100498A1 (en) 2012-12-21 2014-06-26 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
PT2935303T (pt) 2012-12-21 2021-04-30 Alios Biopharma Inc 4'-fluoro-nucleósidos, 4'-fluoro-nucleótidos e seus análogos para o tratamento de hcv
TW201532606A (zh) 2013-04-05 2015-09-01 Alios Biopharma Inc 使用化合物之組合治療ｃ型肝炎病毒感染
WO2014209979A1 (en) 2013-06-26 2014-12-31 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
ES2685591T3 (es) 2013-06-26 2018-10-10 Alios Biopharma, Inc. Nucleósidos, nucleótidos sustituidos y análogos de los mismos
SG11201602595TA (en) 2013-10-11 2016-04-28 Alios Biopharma Inc Substituted nucleosides, nucleotides and analogs thereof
NZ727582A (en) 2014-06-24 2018-06-29 Alios Biopharma Inc Substituted nucleosides, nucleotides and analogs thereof
HUE051986T2 (hu) 2014-06-24 2021-04-28 Janssen Biopharma Inc Helyettesített nukleozidok, nukleotidek és analógjaik virális fertõzés kezelésére való alkalmazásra
AU2015301334A1 (en) * 2014-08-05 2017-02-23 Alios Biopharma, Inc. Combination therapy for treating a paramyxovirus
WO2016069489A1 (en) 2014-10-28 2016-05-06 Alios Biopharma, Inc. Methods of preparing substituted nucleoside analogs
MA41441A (fr) 2014-12-19 2017-12-12 Alios Biopharma Inc Nucléosides substitués, nucléotides et analogues de ceux-ci
MA41213A (fr) 2014-12-19 2017-10-24 Alios Biopharma Inc Nucléosides substitués, nucléotides et analogues de ceux-ci
CA2979216A1 (en) 2015-03-11 2016-09-15 Alios Biopharma, Inc. Aza-pyridone compounds and uses thereof
WO2018081449A1 (en) * 2016-10-27 2018-05-03 Alios Biopharma, Inc. Methods for treating respiratory syncytial virus infection
WO2018222774A1 (en) * 2017-05-30 2018-12-06 Alios Biopharma, Inc. Methods for treating pneumoviruses
CN113462656B (zh) * 2021-03-24 2022-09-30 兰州生物制品研究所有限责任公司 一种人三型副流感病毒冷适应温度敏感株及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69233607T2 (de) * 1991-08-26 2006-11-30 The Scripps Research Institute, La Jolla Peptide, die die zytotoxische T-Lymphozyte Antwort gegen Hepatitis-B-Virus induzieren
JPH0859508A (ja) * 1994-08-16 1996-03-05 Teijin Ltd サイトメガロウイルス網膜炎予防または治療剤
CN102958933B (zh) * 2010-06-24 2016-02-03 吉里德科学公司 作为抗病毒药的吡唑并[1,5-a]嘧啶类
WO2013096679A1 (en) * 2011-12-22 2013-06-27 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
ME03502B (me) * 2012-03-21 2020-04-20 Janssen Biopharma Inc Supstituisani nukleozidi, nukleotidi i njihovi analozi

Also Published As

Publication number Publication date
RU2017105470A (ru) 2018-08-22
EP3171878A4 (en) 2018-03-14
WO2016014398A1 (en) 2016-01-28
AU2015294343A1 (en) 2017-02-02
EP3171878A1 (en) 2017-05-31
CA2955604A1 (en) 2016-01-28
RU2017105470A3 (es) 2019-02-28
TW201609104A (zh) 2016-03-16
KR20170031231A (ko) 2017-03-20
US20160022724A1 (en) 2016-01-28
BR112017001162A2 (pt) 2017-11-14
JP2017525681A (ja) 2017-09-07
MA40403A (fr) 2017-05-31
CL2017000156A1 (es) 2017-11-03

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