ZA201409253B - Virus filtration of cell culture media - Google Patents

Virus filtration of cell culture media

Info

Publication number
ZA201409253B
ZA201409253B ZA2014/09253A ZA201409253A ZA201409253B ZA 201409253 B ZA201409253 B ZA 201409253B ZA 2014/09253 A ZA2014/09253 A ZA 2014/09253A ZA 201409253 A ZA201409253 A ZA 201409253A ZA 201409253 B ZA201409253 B ZA 201409253B
Authority
ZA
South Africa
Prior art keywords
cell culture
culture media
virus filtration
virus
filtration
Prior art date
Application number
ZA2014/09253A
Other languages
English (en)
Inventor
Wolfgang Mundt
Manfred Reiter
Leopold Grillberger
Artur Mitterer
Meinhard Hasslacher
Thomas Kreil
Original Assignee
Baxter Int
Baxter Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int, Baxter Healthcare Sa filed Critical Baxter Int
Publication of ZA201409253B publication Critical patent/ZA201409253B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/022Filtration
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/26Conditioning fluids entering or exiting the reaction vessel
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/02Filters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Filtering Materials (AREA)
ZA2014/09253A 2012-06-21 2014-12-15 Virus filtration of cell culture media ZA201409253B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261662814P 2012-06-21 2012-06-21
PCT/US2013/045663 WO2013192009A1 (en) 2012-06-21 2013-06-13 Virus filtration of cell culture media

Publications (1)

Publication Number Publication Date
ZA201409253B true ZA201409253B (en) 2022-05-25

Family

ID=48672845

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2014/09253A ZA201409253B (en) 2012-06-21 2014-12-15 Virus filtration of cell culture media

Country Status (27)

Country Link
US (3) US9670456B2 (https=)
EP (2) EP3103861B1 (https=)
JP (3) JP6220392B2 (https=)
KR (2) KR102008048B1 (https=)
CN (2) CN108795724A (https=)
AR (1) AR092847A1 (https=)
AU (2) AU2013277532B2 (https=)
BR (1) BR112014031842B1 (https=)
CA (1) CA2876473C (https=)
CO (1) CO7151484A2 (https=)
DK (2) DK3103861T3 (https=)
EA (2) EA201990887A1 (https=)
ES (2) ES2829968T3 (https=)
HR (1) HRP20161435T1 (https=)
HU (1) HUE031601T2 (https=)
IL (2) IL236073B (https=)
IN (1) IN2014DN10441A (https=)
MX (2) MX347319B (https=)
MY (2) MY195362A (https=)
NZ (1) NZ629083A (https=)
PL (2) PL3103861T3 (https=)
PT (2) PT2732020T (https=)
SG (2) SG10201701721TA (https=)
SI (1) SI2732020T1 (https=)
TW (2) TWI609962B (https=)
WO (1) WO2013192009A1 (https=)
ZA (1) ZA201409253B (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3103861T3 (da) * 2012-06-21 2020-11-16 Baxalta GmbH Virusfiltrering af cellekulturmedier
AR095196A1 (es) 2013-03-15 2015-09-30 Regeneron Pharma Medio de cultivo celular libre de suero
SG10201507931QA (en) * 2014-12-22 2016-07-28 Emd Millipore Corp Removal of microorganisms from cell culture media
US20180072769A1 (en) * 2015-03-23 2018-03-15 Alexion Pharmaceuticals, Inc. Virus filtration
EP3015542A1 (de) * 2015-05-07 2016-05-04 Bayer Technology Services GmbH Modulare anlage und verfahren zur kontinuierlichen, keimreduzierten produktion und/oder aufbereitung eines produktes
TW202440904A (zh) 2015-08-04 2024-10-16 美商再生元醫藥公司 補充牛磺酸之細胞培養基及用法(二)
WO2017180814A1 (en) * 2016-04-15 2017-10-19 Boehringer Ingelheim International Gmbh Cell retention device and method
WO2018107099A1 (en) * 2016-12-09 2018-06-14 Lonza Ltd Method for the reduction of viral titer in pharmaceuticals
KR102659791B1 (ko) * 2017-07-06 2024-04-23 리제너론 파마슈티칼스 인코포레이티드 당단백질을 만들기 위한 세포 배양 과정
TWI846694B (zh) * 2018-05-04 2024-07-01 美商健臻公司 具有過濾系統的灌注式生物反應器
SG11202109877RA (en) 2019-03-11 2021-10-28 Genzyme Corp Tangential viral filtration
KR20210149117A (ko) * 2019-04-03 2021-12-08 젠자임 코포레이션 재조합 단백질의 연속 생산
US12297451B1 (en) 2019-10-25 2025-05-13 Regeneron Pharmaceuticals, Inc. Cell culture medium
US20230181796A1 (en) * 2020-05-14 2023-06-15 North Carolina State University Fast automated approach for the derivation of acellular extracellular matrix scaffolds from tissues
CA3197305A1 (en) * 2020-10-02 2022-04-07 Regeneron Pharmaceuticals, Inc. Continuous virus retentive filtration
WO2025019797A2 (en) * 2023-07-19 2025-01-23 Hatchless Inc. System and method for low-cost sterilization of liquids

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0422874A (ja) * 1990-05-16 1992-01-27 Matsushita Electric Ind Co Ltd 波形表示装置
GB2352652A (en) * 1999-08-06 2001-02-07 Fsm Technologies Ltd Pre-treating hollow fibre membranes for micro-organism detection
US6485686B1 (en) * 1999-09-17 2002-11-26 The United States Of America As Represented By The Secretary Of The Army Method and apparatus for counting submicron sized particles
US6861001B2 (en) 1999-12-02 2005-03-01 The General Hospital Corporation Methods for removal, purification, and concentration of viruses, and methods of therapy based thereupon
US6485688B1 (en) 2000-04-24 2002-11-26 General Electric Company On-line sparging sampling and monitoring systems and methods
US6835311B2 (en) * 2002-01-31 2004-12-28 Koslow Technologies Corporation Microporous filter media, filtration systems containing same, and methods of making and using
US6630016B2 (en) * 2002-01-31 2003-10-07 Koslow Technologies Corp. Microporous filter media, filtration systems containing same, and methods of making and using
ES2214967B1 (es) 2003-03-06 2005-06-16 Probitas Pharma, S.A Procedimiento para la eliminacion de virus en soluciones de fibrinogeno y fibrinogeno obtenido por dicho procedimiento.
EP1711513B1 (en) 2003-12-01 2014-07-02 Novo Nordisk Health Care AG Nanofiltration of factor vii solutions to remove virus
DE102005047301B4 (de) * 2005-09-30 2009-04-16 Sartorius Stedim Biotech Gmbh Verfahren zum Nachweis der Virenabreicherung für die Validierung von Filtern und Filtrationsprozessen
US20070084788A1 (en) 2005-10-14 2007-04-19 Millipore Corporation Ultrafiltration membranes and methods of making and use of ultrafiltration membranes
US8309029B1 (en) * 2009-03-26 2012-11-13 The United States Of America As Represented By The Secretary Of The Army Virus and particulate separation from solution
US8945895B2 (en) * 2009-07-31 2015-02-03 Baxter International Inc. Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof
AU2010284116B9 (en) * 2009-08-20 2015-03-26 Takeda Pharmaceutical Company Limited Purification of VWF for increased removal of non-lipid enveloped viruses
DK3103861T3 (da) * 2012-06-21 2020-11-16 Baxalta GmbH Virusfiltrering af cellekulturmedier

Also Published As

Publication number Publication date
EP2732020B1 (en) 2016-08-10
PT2732020T (pt) 2016-11-10
US20170260498A1 (en) 2017-09-14
AU2013277532B2 (en) 2017-06-15
KR20190092618A (ko) 2019-08-07
EP3103861A1 (en) 2016-12-14
HK1198335A1 (zh) 2015-04-02
HK1231502A1 (en) 2017-12-22
BR112014031842B1 (pt) 2020-09-15
ES2829968T3 (es) 2021-06-02
TW201816105A (zh) 2018-05-01
CA2876473C (en) 2021-05-11
DK2732020T3 (en) 2016-11-28
IL236073A0 (en) 2015-01-29
JP2019022526A (ja) 2019-02-14
EA201990887A1 (ru) 2019-08-30
EA201590059A1 (ru) 2015-04-30
MX386767B (es) 2025-03-19
SI2732020T1 (sl) 2017-03-31
AR092847A1 (es) 2015-05-06
WO2013192009A1 (en) 2013-12-27
JP6557706B2 (ja) 2019-08-07
CN104640969A (zh) 2015-05-20
EP3103861B1 (en) 2020-09-30
TW201412986A (zh) 2014-04-01
US20200277565A1 (en) 2020-09-03
HRP20161435T1 (hr) 2017-02-24
AU2013277532A1 (en) 2015-01-15
IL263479B (en) 2020-08-31
CO7151484A2 (es) 2014-12-29
SG10201701721TA (en) 2017-04-27
TWI698522B (zh) 2020-07-11
PL2732020T3 (pl) 2017-06-30
EA033006B1 (ru) 2019-08-30
MY195362A (en) 2023-01-16
HUE031601T2 (hu) 2017-07-28
JP2015529447A (ja) 2015-10-08
CN108795724A (zh) 2018-11-13
BR112014031842A2 (pt) 2017-08-22
IL236073B (en) 2019-01-31
TWI609962B (zh) 2018-01-01
US11421202B2 (en) 2022-08-23
DK3103861T3 (da) 2020-11-16
NZ629083A (en) 2016-11-25
KR102008048B1 (ko) 2019-08-06
MX347319B (es) 2017-04-21
JP6220392B2 (ja) 2017-10-25
JP2017184765A (ja) 2017-10-12
US20130344535A1 (en) 2013-12-26
EP2732020A1 (en) 2014-05-21
CA2876473A1 (en) 2013-12-27
KR20150032709A (ko) 2015-03-27
PT3103861T (pt) 2020-11-16
SG11201408490PA (en) 2015-01-29
MY173835A (en) 2020-02-24
PL3103861T3 (pl) 2021-03-22
AU2017228547B2 (en) 2019-02-21
MX2014015950A (es) 2015-07-17
AU2017228547A1 (en) 2017-10-05
US9670456B2 (en) 2017-06-06
IN2014DN10441A (https=) 2015-08-21
IL263479A (en) 2019-01-31
ES2601429T3 (es) 2017-02-15

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