ZA201404610B - Method for treating alveolar bone loss through the use of anti-sclerostin antibodies - Google Patents

Method for treating alveolar bone loss through the use of anti-sclerostin antibodies

Info

Publication number
ZA201404610B
ZA201404610B ZA2014/04610A ZA201404610A ZA201404610B ZA 201404610 B ZA201404610 B ZA 201404610B ZA 2014/04610 A ZA2014/04610 A ZA 2014/04610A ZA 201404610 A ZA201404610 A ZA 201404610A ZA 201404610 B ZA201404610 B ZA 201404610B
Authority
ZA
South Africa
Prior art keywords
bone loss
alveolar bone
sclerostin antibodies
treating alveolar
treating
Prior art date
Application number
ZA2014/04610A
Other languages
English (en)
Inventor
Min Liu
William V Giannobile
Hua Zhu Ke
Original Assignee
Amgen Inc
Univ Michigan Regents
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47429046&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA201404610(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc, Univ Michigan Regents filed Critical Amgen Inc
Publication of ZA201404610B publication Critical patent/ZA201404610B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA2014/04610A 2011-12-28 2014-06-23 Method for treating alveolar bone loss through the use of anti-sclerostin antibodies ZA201404610B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161580964P 2011-12-28 2011-12-28
PCT/US2012/068975 WO2013101451A1 (en) 2011-12-28 2012-12-11 Method of treating alvelor bone loss through the use of anti-sclerostin antibodies

Publications (1)

Publication Number Publication Date
ZA201404610B true ZA201404610B (en) 2017-11-29

Family

ID=47429046

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2014/04610A ZA201404610B (en) 2011-12-28 2014-06-23 Method for treating alveolar bone loss through the use of anti-sclerostin antibodies

Country Status (19)

Country Link
US (3) US9657090B2 (OSRAM)
EP (2) EP2797953B1 (OSRAM)
JP (3) JP6363954B2 (OSRAM)
KR (3) KR20190120401A (OSRAM)
CN (2) CN104039828B (OSRAM)
AR (1) AR089509A1 (OSRAM)
AU (3) AU2012362898B2 (OSRAM)
BR (1) BR112014016108A2 (OSRAM)
CA (1) CA2858974A1 (OSRAM)
CL (1) CL2014001719A1 (OSRAM)
EA (2) EA202091676A1 (OSRAM)
ES (1) ES2813524T3 (OSRAM)
IL (2) IL232942B (OSRAM)
IN (1) IN2014CN04634A (OSRAM)
MX (1) MX354270B (OSRAM)
SG (2) SG10201509629QA (OSRAM)
TW (3) TW202114733A (OSRAM)
WO (1) WO2013101451A1 (OSRAM)
ZA (1) ZA201404610B (OSRAM)

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US7592429B2 (en) * 2005-05-03 2009-09-22 Ucb Sa Sclerostin-binding antibody
TWI636994B (zh) * 2010-10-27 2018-10-01 安美基公司 Dkk1抗體及使用方法
JP2014511842A (ja) 2011-03-25 2014-05-19 アムジエン・インコーポレーテツド 抗スクレロスチン抗体結晶およびその製剤
IN2014CN04634A (OSRAM) * 2011-12-28 2015-09-18 Amgen Inc
WO2015008491A1 (ja) * 2013-07-19 2015-01-22 株式会社アクシオン・ジャパン パノラマ画像撮影装置及び同装置で用いる画像診断方法
LT3269735T (lt) * 2015-03-13 2020-12-28 Jiangsu Hengrui Medicine Co. Ltd. Antikūnas prieš sklerostiną, antigeną surišantis fragmentas ir jų medicininis panaudojimas
JP2020502218A (ja) 2016-12-21 2020-01-23 メレオ バイオファーマ 3 リミテッド 骨形成不全症の処置における抗スクレロスチン抗体の使用
WO2019154410A1 (zh) * 2018-02-12 2019-08-15 翼高生物科技有限公司 针对骨硬化蛋白的适体及其用途
US12062170B2 (en) * 2018-10-30 2024-08-13 Diagnocat Inc System and method for classifying a tooth condition based on landmarked anthropomorphic measurements
US12229964B2 (en) * 2018-10-30 2025-02-18 Diagnocat Inc. Probabilistic segmentation of volumetric images
US20230130132A1 (en) * 2020-03-26 2023-04-27 Bone Sci. Bio Ltd. Pharmaceutical compositions comprising amphiphilic peptides and methods of use thereof
KR102472582B1 (ko) * 2020-08-20 2022-11-30 한림대학교 산학협력단 인공관절 마모편에 의한 활막염과 골용해의 진단 및 치료 방법
MX2023003644A (es) * 2020-09-28 2023-04-19 Angitia Biomedicines Ltd Constructos de anti-esclerostina y usos de los mismos.

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Also Published As

Publication number Publication date
JP2017214359A (ja) 2017-12-07
WO2013101451A8 (en) 2014-06-26
US20140314776A1 (en) 2014-10-23
JP2015504887A (ja) 2015-02-16
EP2797953A1 (en) 2014-11-05
KR102033669B1 (ko) 2019-10-18
CN104039828A (zh) 2014-09-10
CN104039828B (zh) 2017-07-21
TW201811364A (zh) 2018-04-01
AU2012362898B2 (en) 2017-11-09
IL232942B (en) 2018-10-31
MX354270B (es) 2018-02-21
CN107126560A (zh) 2017-09-05
KR20190120401A (ko) 2019-10-23
US20170281761A1 (en) 2017-10-05
TWI706787B (zh) 2020-10-11
WO2013101451A1 (en) 2013-07-04
TW201330859A (zh) 2013-08-01
AU2018200649A1 (en) 2018-02-15
SG11201403718YA (en) 2014-07-30
TW202114733A (zh) 2021-04-16
AU2019275548A1 (en) 2020-01-02
EP3712168A2 (en) 2020-09-23
JP6363954B2 (ja) 2018-07-25
CA2858974A1 (en) 2013-07-04
EP2797953B1 (en) 2020-06-03
IL232942A0 (en) 2014-07-31
AU2012362898A1 (en) 2014-07-24
US9657090B2 (en) 2017-05-23
KR20200056473A (ko) 2020-05-22
EA202091676A1 (ru) 2021-01-29
KR20140116089A (ko) 2014-10-01
AR089509A1 (es) 2014-08-27
ES2813524T3 (es) 2021-03-24
US20180169234A1 (en) 2018-06-21
JP2019031567A (ja) 2019-02-28
BR112014016108A2 (pt) 2018-09-11
IL259939B (en) 2020-05-31
EA036740B1 (ru) 2020-12-15
HK1198367A1 (zh) 2015-04-10
US9913900B2 (en) 2018-03-13
SG10201509629QA (en) 2015-12-30
CL2014001719A1 (es) 2014-11-03
EA201491286A1 (ru) 2014-09-30
IN2014CN04634A (OSRAM) 2015-09-18
EP3712168A3 (en) 2020-10-14
IL259939A (en) 2018-07-31
MX2014007965A (es) 2014-11-25

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