ZA201401993B - Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment - Google Patents

Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment

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Publication number
ZA201401993B
ZA201401993B ZA2014/01993A ZA201401993A ZA201401993B ZA 201401993 B ZA201401993 B ZA 201401993B ZA 2014/01993 A ZA2014/01993 A ZA 2014/01993A ZA 201401993 A ZA201401993 A ZA 201401993A ZA 201401993 B ZA201401993 B ZA 201401993B
Authority
ZA
South Africa
Prior art keywords
same
transplantation
cells
methods
disease treatment
Prior art date
Application number
ZA2014/01993A
Other languages
English (en)
Inventor
Esther Bachar-Lustig
Noga Or-Geva
Ran Afik
Assaf Lask
Eran Ophir
Yaki Eidelstein
Yair Reisner
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of ZA201401993B publication Critical patent/ZA201401993B/en

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0637—Immunosuppressive T lymphocytes, e.g. regulatory T cells or Treg
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
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    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2321—Interleukin-21 (IL-21)
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
    • C12N2502/1121—Dendritic cells

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  • Health & Medical Sciences (AREA)
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  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Mycology (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
ZA2014/01993A 2011-09-08 2014-03-19 Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment ZA201401993B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161532172P 2011-09-08 2011-09-08
PCT/IL2012/050354 WO2013035099A1 (en) 2011-09-08 2012-09-06 Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment

Publications (1)

Publication Number Publication Date
ZA201401993B true ZA201401993B (en) 2017-08-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2014/01993A ZA201401993B (en) 2011-09-08 2014-03-19 Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment

Country Status (14)

Country Link
US (3) US20140212398A1 (cg-RX-API-DMAC7.html)
EP (1) EP2753351B1 (cg-RX-API-DMAC7.html)
JP (1) JP6196620B2 (cg-RX-API-DMAC7.html)
KR (1) KR102073901B1 (cg-RX-API-DMAC7.html)
CN (1) CN103930130B (cg-RX-API-DMAC7.html)
AU (1) AU2012305931B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014005355B1 (cg-RX-API-DMAC7.html)
CA (1) CA2848121C (cg-RX-API-DMAC7.html)
ES (1) ES2640813T3 (cg-RX-API-DMAC7.html)
MX (1) MX351226B (cg-RX-API-DMAC7.html)
RU (1) RU2636503C2 (cg-RX-API-DMAC7.html)
SG (1) SG11201400513PA (cg-RX-API-DMAC7.html)
WO (1) WO2013035099A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201401993B (cg-RX-API-DMAC7.html)

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EP2812431B1 (en) 2012-02-09 2019-07-17 Baylor College Of Medicine Pepmixes to generate multiviral ctls with broad specificity
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US11179448B2 (en) 2015-07-16 2021-11-23 Yeda Research And Development Co. Ltd. Genetically modified anti-third party central memory T cells and use of same in immunotherapy
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