PL2549995T3 - Zastosowanie anatabiny w leczeniu stanów zapalnych i metody syntezy anatabiny - Google Patents

Zastosowanie anatabiny w leczeniu stanów zapalnych i metody syntezy anatabiny

Info

Publication number
PL2549995T3
PL2549995T3 PL11714880T PL11714880T PL2549995T3 PL 2549995 T3 PL2549995 T3 PL 2549995T3 PL 11714880 T PL11714880 T PL 11714880T PL 11714880 T PL11714880 T PL 11714880T PL 2549995 T3 PL2549995 T3 PL 2549995T3
Authority
PL
Poland
Prior art keywords
anatabine
methods
synthesizing
treat inflammation
inflammation
Prior art date
Application number
PL11714880T
Other languages
English (en)
Inventor
Jonnie R. Williams
Tom Thomas Puthiaparampil
Thomas Kanathkunn David
Muppala Sarveswara Raju
Original Assignee
Philip Morris Products S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/729,346 external-priority patent/US8207346B2/en
Application filed by Philip Morris Products S.A. filed Critical Philip Morris Products S.A.
Publication of PL2549995T3 publication Critical patent/PL2549995T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL11714880T 2010-03-23 2011-03-23 Zastosowanie anatabiny w leczeniu stanów zapalnych i metody syntezy anatabiny PL2549995T3 (pl)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US12/729,346 US8207346B2 (en) 2010-03-23 2010-03-23 Methods of synthesizing anatabine
US38381110P 2010-09-17 2010-09-17
US38444710P 2010-09-20 2010-09-20
US201161439473P 2011-02-04 2011-02-04
US201161439483P 2011-02-04 2011-02-04
PCT/US2011/029613 WO2011119722A2 (en) 2010-03-23 2011-03-23 Use of anatabine to treat inflammation and methods of synthesizing anatabine
EP11714880.9A EP2549995B1 (en) 2010-03-23 2011-03-23 Use of anatabine to treat inflammation and methods of synthesizing anatabine

Publications (1)

Publication Number Publication Date
PL2549995T3 true PL2549995T3 (pl) 2021-09-27

Family

ID=44201080

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11714880T PL2549995T3 (pl) 2010-03-23 2011-03-23 Zastosowanie anatabiny w leczeniu stanów zapalnych i metody syntezy anatabiny

Country Status (8)

Country Link
EP (4) EP2549995B1 (pl)
AU (5) AU2011232478A1 (pl)
CA (1) CA2794097C (pl)
DK (1) DK2549995T3 (pl)
ES (1) ES2869851T3 (pl)
PL (1) PL2549995T3 (pl)
PT (1) PT2549995T (pl)
WO (1) WO2011119722A2 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012302257A1 (en) * 2011-08-29 2014-03-13 Rcp Development, Inc. Products for anti-inflammation support
EP2793026A1 (en) 2013-04-18 2014-10-22 Centre National de la Recherche Scientifique (CNRS) New method for monitoring cancer and/or inflammatory reaction based on relb phosphorylation
AU2019407661A1 (en) 2018-12-17 2021-04-29 Philip Morris Products S.A. 3-(1,2,3,6-tetrahydropyridin-2-yl)pyridine glutarate or a pharmaceutically acceptable solvate thereof
KR20230024889A (ko) 2020-06-15 2023-02-21 필립모리스 프로덕츠 에스.에이. 아나타빈 분말 조성물
US20230301919A1 (en) 2020-09-03 2023-09-28 Philip Morris Products S.A. Freeze dried low hygroscopicity active powder compositions
US20230346696A1 (en) 2020-09-03 2023-11-02 Philip Morris Products S.A. Spray dried low hygroscopicity active powder compositions
KR20230061366A (ko) 2020-09-03 2023-05-08 필립모리스 프로덕츠 에스.에이. 저 흡습성 활성 분말 조성물
CN113880802A (zh) * 2021-11-09 2022-01-04 深圳萨特瓦生物科技有限公司 酒石酸-尼古丁盐及其制备方法与应用、无水酒石酸晶体的制备方法
WO2023117661A1 (en) 2021-12-20 2023-06-29 Philip Morris Products S.A. Increasing anatabine in tobacco leaf by regulating methyl putrescine oxidase
CN115594662A (zh) * 2022-10-19 2023-01-13 昆明理工大学(Cn) 一种(s)-烟碱的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3901248A (en) 1970-07-22 1975-08-26 Leo Ab Chewable smoking substitute composition
DE4002784C1 (pl) 1990-01-31 1991-04-18 B.A.T. Cigarettenfabriken Gmbh, 2000 Hamburg, De
US5065775A (en) 1990-02-23 1991-11-19 R. J. Reynolds Tobacco Company Tobacco processing
US5276043A (en) * 1992-04-10 1994-01-04 R. J. Reynolds Tobacco Company Method for treatment of neurodegenerative diseases
US5942244A (en) 1997-07-31 1999-08-24 Farmo-Nat Ltd. Local oral herbal slow release tablets
EP1083913A4 (en) * 1998-06-05 2004-03-17 Regent Court Technologies MONOAMINE OXIDASE (MAO) INHIBITORS AND USES THEREOF
WO2001094951A2 (en) * 2000-06-08 2001-12-13 Board Of Regents, The University Of Texas System Inhibitors of c-reactive protein induced inflammation
CA2341952A1 (en) * 2001-03-23 2002-09-23 Universite Laval Nicotinic receptor agonists for the treatment of inflammatory pulmonary diseases
JP5179011B2 (ja) 2002-10-09 2013-04-10 ディーエムアイ バイオサイエンシズ インコーポレイテッド 胎盤虚血および多臓器不全のモニタリング
ES2439229T3 (es) 2004-10-06 2014-01-22 The Brigham And Women's Hospital, Inc. Relevancia de niveles logrados de marcadores de inflamación sistémica tras el tratamiento
US20080003213A1 (en) * 2006-05-22 2008-01-03 Jan Lessem Methods and compositions for the treatment of diseases or conditions associated with increased C-reactive protein, interleukin-6, or interferon-gamma levels
US8841329B2 (en) * 2008-09-11 2014-09-23 Dignity Health Nicotinic attenuation of CNS inflammation and autoimmunity
US8151804B2 (en) 2008-12-23 2012-04-10 Williams Jonnie R Tobacco curing method

Also Published As

Publication number Publication date
AU2017201593A1 (en) 2017-03-30
AU2020257090B2 (en) 2021-12-02
AU2019200103A1 (en) 2019-01-31
EP3524245A1 (en) 2019-08-14
PT2549995T (pt) 2021-07-29
EP3524246A1 (en) 2019-08-14
AU2020257090A1 (en) 2020-11-19
AU2019200102B2 (en) 2020-07-30
EP3871674A1 (en) 2021-09-01
AU2019200102A1 (en) 2019-01-31
EP2549995A2 (en) 2013-01-30
WO2011119722A3 (en) 2011-12-29
AU2017201593B2 (en) 2019-02-28
WO2011119722A2 (en) 2011-09-29
ES2869851T3 (es) 2021-10-26
DK2549995T3 (da) 2021-05-25
AU2011232478A1 (en) 2015-11-19
CA2794097C (en) 2016-08-09
CA2794097A1 (en) 2011-09-29
AU2019200103B2 (en) 2020-07-30
EP2549995B1 (en) 2021-04-21
AU2017201593C1 (en) 2019-06-27

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