ZA201102637B - Cd86 antagonist multi-target binding proteins - Google Patents
Cd86 antagonist multi-target binding proteinsInfo
- Publication number
- ZA201102637B ZA201102637B ZA2011/02637A ZA201102637A ZA201102637B ZA 201102637 B ZA201102637 B ZA 201102637B ZA 2011/02637 A ZA2011/02637 A ZA 2011/02637A ZA 201102637 A ZA201102637 A ZA 201102637A ZA 201102637 B ZA201102637 B ZA 201102637B
- Authority
- ZA
- South Africa
- Prior art keywords
- binding proteins
- target binding
- antagonist multi
- antagonist
- target
- Prior art date
Links
- 229940121764 CD86 antagonist Drugs 0.000 title 1
- 102000014914 Carrier Proteins Human genes 0.000 title 1
- 108091008324 binding proteins Proteins 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/52—Cytokines; Lymphokines; Interferons
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/244—Interleukins [IL]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/244—Interleukins [IL]
- C07K16/248—IL-6
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C12N15/62—DNA sequences coding for fusion proteins
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- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
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- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
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- Veterinary Medicine (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
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- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Diabetes (AREA)
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Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10231908P | 2008-10-02 | 2008-10-02 | |
| US10232708P | 2008-10-02 | 2008-10-02 | |
| US10233108P | 2008-10-02 | 2008-10-02 | |
| US10231508P | 2008-10-02 | 2008-10-02 | |
| US10230708P | 2008-10-02 | 2008-10-02 | |
| US10233608P | 2008-10-02 | 2008-10-02 | |
| US10233408P | 2008-10-02 | 2008-10-02 | |
| US10229708P | 2008-10-02 | 2008-10-02 | |
| US10228808P | 2008-10-02 | 2008-10-02 | |
| PCT/US2009/059446 WO2010040105A2 (en) | 2008-10-02 | 2009-10-02 | Cd86 antagonist multi-target binding proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201102637B true ZA201102637B (en) | 2016-09-28 |
Family
ID=41557444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2011/02637A ZA201102637B (en) | 2008-10-02 | 2011-04-08 | Cd86 antagonist multi-target binding proteins |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US9493564B2 (OSRAM) |
| EP (2) | EP3281955A1 (OSRAM) |
| JP (4) | JP5840494B2 (OSRAM) |
| KR (5) | KR20170091801A (OSRAM) |
| CN (2) | CN107056951A (OSRAM) |
| AU (4) | AU2009298131B2 (OSRAM) |
| BR (1) | BRPI0920749A8 (OSRAM) |
| CA (2) | CA3038442A1 (OSRAM) |
| CY (1) | CY1119874T1 (OSRAM) |
| DK (1) | DK2344540T3 (OSRAM) |
| EA (1) | EA024877B1 (OSRAM) |
| ES (1) | ES2657220T3 (OSRAM) |
| HK (1) | HK1251000A1 (OSRAM) |
| HR (1) | HRP20180045T1 (OSRAM) |
| LT (1) | LT2344540T (OSRAM) |
| MX (1) | MX338825B (OSRAM) |
| NO (1) | NO2344540T3 (OSRAM) |
| NZ (1) | NZ592420A (OSRAM) |
| PL (1) | PL2344540T3 (OSRAM) |
| PT (1) | PT2344540T (OSRAM) |
| SI (1) | SI2344540T1 (OSRAM) |
| WO (1) | WO2010040105A2 (OSRAM) |
| ZA (1) | ZA201102637B (OSRAM) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7030219B2 (en) | 2000-04-28 | 2006-04-18 | Johns Hopkins University | B7-DC, Dendritic cell co-stimulatory molecules |
| CA2729747A1 (en) * | 2008-07-02 | 2010-01-07 | Emergent Product Development Seattle, Llc | Il6 immunotherapeutics |
| US20110152173A1 (en) * | 2008-07-02 | 2011-06-23 | Emergent Product Development Seattle ,LLC | TNF-a ANTAGONIST MULTI-TARGET BINDING PROTEINS |
| ES2657220T3 (es) * | 2008-10-02 | 2018-03-02 | Aptevo Research And Development Llc | Proteínas de unión multi-diana antagonistas de CD86 |
| EA032828B1 (ru) * | 2008-10-10 | 2019-07-31 | Аптево Рисёрч Энд Девелопмент Ллс | Иммунотерапевтические средства против комплекса tcr |
| JP2013512251A (ja) * | 2009-11-24 | 2013-04-11 | アンプリミューン、インコーポレーテッド | Pd−l1/pd−l2の同時阻害 |
| US11246915B2 (en) | 2010-09-15 | 2022-02-15 | Applied Molecular Transport Inc. | Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo |
| CA2848656C (en) | 2010-09-15 | 2017-10-10 | Randall J. Mrsny | Systems and methods of delivery of bioactive agents using bacterial toxin-derived transport sequences |
| CN101962413B (zh) * | 2010-09-21 | 2013-03-13 | 中国科学技术大学 | 具有透皮能力和白细胞介素-10活性的融合蛋白及其编码基因与应用 |
| CA2833019A1 (en) * | 2011-04-22 | 2012-10-26 | Emergent Product Development Seattle, Llc | Prostate-specific membrane antigen binding proteins and related compositions and methods |
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| CN102958942A (zh) | 2009-12-29 | 2013-03-06 | 新兴产品开发西雅图有限公司 | 异二聚体结合蛋白及其应用 |
| WO2012045334A1 (en) | 2010-10-05 | 2012-04-12 | Synthon Bv | Biologically active il-10 fusion proteins |
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2009
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