ZA201005909B - Compounds that are erk inhibitors - Google Patents

Compounds that are erk inhibitors

Info

Publication number
ZA201005909B
ZA201005909B ZA2010/05909A ZA201005909A ZA201005909B ZA 201005909 B ZA201005909 B ZA 201005909B ZA 2010/05909 A ZA2010/05909 A ZA 2010/05909A ZA 201005909 A ZA201005909 A ZA 201005909A ZA 201005909 B ZA201005909 B ZA 201005909B
Authority
ZA
South Africa
Prior art keywords
compounds
erk inhibitors
erk
inhibitors
Prior art date
Application number
ZA2010/05909A
Other languages
English (en)
Inventor
Alan B Cooper
Yang Nan
Yongqi Deng
Jr Gerald W Shipps
Neng-Yang Shih
Hugh Y Zhu
Joseph M Kelly
Subrahmanyam Gudipati
Ronald J Doll
Mehul F Patel
Jagdish A Desai
James J-S Wang
Sunil Paliwal
Hon-Chung Tsui
Sobhana Babu Boga
Abdul-Basit Alhassan
Xiaolei Gao
Liang Zhu
Xin Yao
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40601237&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA201005909(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of ZA201005909B publication Critical patent/ZA201005909B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA2010/05909A 2008-02-21 2010-08-18 Compounds that are erk inhibitors ZA201005909B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3040708P 2008-02-21 2008-02-21
PCT/US2009/034447 WO2009105500A1 (en) 2008-02-21 2009-02-19 Compounds that are erk inhibitors

Publications (1)

Publication Number Publication Date
ZA201005909B true ZA201005909B (en) 2014-03-26

Family

ID=40601237

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA2010/05909A ZA201005909B (en) 2008-02-21 2010-08-18 Compounds that are erk inhibitors
ZA2014/00396A ZA201400396B (en) 2008-02-21 2014-01-17 Compounds that are erk inhibitors

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA2014/00396A ZA201400396B (en) 2008-02-21 2014-01-17 Compounds that are erk inhibitors

Country Status (23)

Country Link
US (1) US8716483B2 (OSRAM)
EP (1) EP2260031B1 (OSRAM)
JP (1) JP5276676B2 (OSRAM)
KR (1) KR20100117123A (OSRAM)
CN (1) CN102015693B (OSRAM)
AR (1) AR070460A1 (OSRAM)
AU (1) AU2009215534B8 (OSRAM)
BR (1) BRPI0908120A8 (OSRAM)
CA (1) CA2714479A1 (OSRAM)
CL (1) CL2009000394A1 (OSRAM)
CO (1) CO6300939A2 (OSRAM)
EC (1) ECSP10010415A (OSRAM)
ES (1) ES2556353T3 (OSRAM)
IL (1) IL207530A (OSRAM)
MX (1) MX2010009268A (OSRAM)
MY (1) MY152271A (OSRAM)
NZ (1) NZ587504A (OSRAM)
PE (1) PE20091491A1 (OSRAM)
RU (1) RU2525389C2 (OSRAM)
SG (1) SG188179A1 (OSRAM)
TW (1) TWI398441B (OSRAM)
WO (1) WO2009105500A1 (OSRAM)
ZA (2) ZA201005909B (OSRAM)

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US8999957B2 (en) * 2010-06-24 2015-04-07 Merck Sharp & Dohme Corp. Heterocyclic compounds as ERK inhibitors
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RU2712148C2 (ru) * 2014-12-19 2020-01-24 Мерк Шарп И Доум Корп. (s)-n-(3-(6-изопропоксипиридин-3-ил)-1h-индазол-5-ил)-1-(2-(4-(4-(1-метил-1h-1,2,4-триазол-3-ил)фенил)-3,6-дигидропиридин-1(2н)-ил)-2-оксоэтил)-3-(метилтио)пирролидин-3-карбоксамидные композиции для фармацевтических препаратов
JP6737533B2 (ja) 2015-04-03 2020-08-12 リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー スピロ環式化合物
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CN106432182B (zh) * 2016-09-06 2019-04-30 铜仁学院 特地唑胺中间体的合成方法
CN109020789B (zh) * 2017-06-12 2021-08-13 浙江医药股份有限公司新昌制药厂 一种制备2-甲氧基丙烯的方法
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Also Published As

Publication number Publication date
IL207530A (en) 2014-08-31
AU2009215534B8 (en) 2014-07-10
TW200948799A (en) 2009-12-01
KR20100117123A (ko) 2010-11-02
WO2009105500A1 (en) 2009-08-27
US8716483B2 (en) 2014-05-06
CA2714479A1 (en) 2009-08-27
BRPI0908120A2 (OSRAM) 2017-08-22
RU2010138635A (ru) 2012-03-27
PE20091491A1 (es) 2009-09-25
AU2009215534A8 (en) 2014-07-10
IL207530A0 (en) 2010-12-30
MY152271A (en) 2014-09-15
CO6300939A2 (es) 2011-07-21
CL2009000394A1 (es) 2011-02-11
BRPI0908120A8 (pt) 2017-10-24
JP2011513225A (ja) 2011-04-28
CN102015693A (zh) 2011-04-13
EP2260031B1 (en) 2015-10-07
ES2556353T8 (es) 2017-10-13
RU2525389C2 (ru) 2014-08-10
EP2260031A1 (en) 2010-12-15
AR070460A1 (es) 2010-04-07
SG188179A1 (en) 2013-03-28
AU2009215534B2 (en) 2014-06-26
JP5276676B2 (ja) 2013-08-28
ZA201400396B (en) 2014-12-23
AU2009215534A1 (en) 2009-08-27
TWI398441B (zh) 2013-06-11
MX2010009268A (es) 2010-09-14
NZ587504A (en) 2012-09-28
CN102015693B (zh) 2014-10-29
ES2556353T3 (es) 2016-01-15
US20110189192A1 (en) 2011-08-04
ECSP10010415A (es) 2010-09-30
AU2009215534A2 (en) 2010-12-23

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