ZA201004769B - Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitors - Google Patents
Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitorsInfo
- Publication number
- ZA201004769B ZA201004769B ZA2010/04769A ZA201004769A ZA201004769B ZA 201004769 B ZA201004769 B ZA 201004769B ZA 2010/04769 A ZA2010/04769 A ZA 2010/04769A ZA 201004769 A ZA201004769 A ZA 201004769A ZA 201004769 B ZA201004769 B ZA 201004769B
- Authority
- ZA
- South Africa
- Prior art keywords
- protein kinase
- kinase inhibitors
- akt protein
- hydroxylated
- pyrimidyl cyclopentanes
- Prior art date
Links
- -1 Hydroxylated pyrimidyl cyclopentanes Chemical class 0.000 title 1
- 229940045988 antineoplastic drug protein kinase inhibitors Drugs 0.000 title 1
- 239000003909 protein kinase inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2009208P | 2008-01-09 | 2008-01-09 | |
| PCT/US2009/030610 WO2009089459A1 (en) | 2008-01-09 | 2009-01-09 | Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201004769B true ZA201004769B (en) | 2011-12-28 |
Family
ID=40552865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2010/04769A ZA201004769B (en) | 2008-01-09 | 2010-07-06 | Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitors |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8835434B2 (https=) |
| EP (1) | EP2247578B1 (https=) |
| JP (1) | JP5346345B2 (https=) |
| KR (1) | KR101624753B1 (https=) |
| CN (1) | CN101932564B (https=) |
| AU (1) | AU2009204025B2 (https=) |
| BR (1) | BRPI0906798A2 (https=) |
| CA (1) | CA2711699A1 (https=) |
| CR (1) | CR11601A (https=) |
| EC (1) | ECSP10010389A (https=) |
| ES (1) | ES2422733T3 (https=) |
| IL (1) | IL206575A0 (https=) |
| MA (1) | MA32183B1 (https=) |
| NZ (1) | NZ586346A (https=) |
| RU (1) | RU2504542C2 (https=) |
| UA (1) | UA100545C2 (https=) |
| WO (1) | WO2009089459A1 (https=) |
| ZA (1) | ZA201004769B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8846683B2 (en) | 2007-07-05 | 2014-09-30 | Array Biopharma, Inc. | Pyrimidyl cyclopentanes as Akt protein kinase inhibitors |
| CN103396409B (zh) * | 2007-07-05 | 2015-03-11 | 阵列生物制药公司 | 作为akt蛋白激酶抑制剂的嘧啶基环戊烷 |
| US9409886B2 (en) | 2007-07-05 | 2016-08-09 | Array Biopharma Inc. | Pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
| US8841304B2 (en) | 2008-01-08 | 2014-09-23 | Array Biopharma, Inc. | Pyrrolopyridines as kinase inhibitors |
| CN101965347B (zh) | 2008-01-09 | 2013-01-02 | 阵列生物制药公司 | 作为激酶抑制剂的吡唑并吡啶 |
| CA2711782C (en) | 2008-01-09 | 2017-01-03 | Array Biopharma Inc. | 5h-cyclopenta[d]pyrimidines as akt protein kinase inhibitors |
| HRP20200992T1 (hr) * | 2012-05-17 | 2020-10-16 | Genentech, Inc. | Amorfni oblik pirimidinil-ciklopentanskog spoja koji inhibira akt, te njegovi pripravci i postupci |
| RU2014151017A (ru) | 2012-05-17 | 2016-07-10 | Аррэй Байофарма Инк. | Способ получения гидроксилированных циклопентилпиримидинов |
| ES2765511T3 (es) * | 2013-11-15 | 2020-06-09 | Hoffmann La Roche | Procesos para la preparación de compuestos de pirimidinilciclopentano |
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| CN103396409B (zh) | 2007-07-05 | 2015-03-11 | 阵列生物制药公司 | 作为akt蛋白激酶抑制剂的嘧啶基环戊烷 |
-
2009
- 2009-01-09 NZ NZ586346A patent/NZ586346A/en not_active IP Right Cessation
- 2009-01-09 RU RU2010132911/04A patent/RU2504542C2/ru active
- 2009-01-09 CN CN2009801019017A patent/CN101932564B/zh active Active
- 2009-01-09 EP EP09700422.0A patent/EP2247578B1/en active Active
- 2009-01-09 ES ES09700422T patent/ES2422733T3/es active Active
- 2009-01-09 BR BRPI0906798-1A patent/BRPI0906798A2/pt not_active Application Discontinuation
- 2009-01-09 JP JP2010542376A patent/JP5346345B2/ja active Active
- 2009-01-09 KR KR1020107017605A patent/KR101624753B1/ko not_active Expired - Fee Related
- 2009-01-09 US US12/811,957 patent/US8835434B2/en active Active
- 2009-01-09 CA CA2711699A patent/CA2711699A1/en not_active Withdrawn
- 2009-01-09 AU AU2009204025A patent/AU2009204025B2/en not_active Ceased
- 2009-01-09 WO PCT/US2009/030610 patent/WO2009089459A1/en not_active Ceased
- 2009-09-01 UA UAA201009871A patent/UA100545C2/ru unknown
-
2010
- 2010-06-23 IL IL206575A patent/IL206575A0/en unknown
- 2010-07-06 ZA ZA2010/04769A patent/ZA201004769B/en unknown
- 2010-07-23 MA MA33047A patent/MA32183B1/fr unknown
- 2010-07-27 CR CR11601A patent/CR11601A/es not_active Application Discontinuation
- 2010-08-06 EC EC2010010389A patent/ECSP10010389A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL206575A0 (en) | 2010-12-30 |
| EP2247578B1 (en) | 2013-05-22 |
| JP2011509308A (ja) | 2011-03-24 |
| US8835434B2 (en) | 2014-09-16 |
| MA32183B1 (fr) | 2011-04-01 |
| JP5346345B2 (ja) | 2013-11-20 |
| WO2009089459A1 (en) | 2009-07-16 |
| CA2711699A1 (en) | 2009-07-16 |
| KR101624753B1 (ko) | 2016-05-26 |
| ES2422733T3 (es) | 2013-09-13 |
| RU2010132911A (ru) | 2012-02-20 |
| KR20100118110A (ko) | 2010-11-04 |
| UA100545C2 (ru) | 2013-01-10 |
| RU2504542C2 (ru) | 2014-01-20 |
| BRPI0906798A2 (pt) | 2015-07-14 |
| ECSP10010389A (es) | 2010-11-30 |
| CR11601A (es) | 2010-08-19 |
| CN101932564B (zh) | 2012-12-26 |
| NZ586346A (en) | 2012-02-24 |
| US20110065716A1 (en) | 2011-03-17 |
| EP2247578A1 (en) | 2010-11-10 |
| AU2009204025B2 (en) | 2014-02-20 |
| CN101932564A (zh) | 2010-12-29 |
| AU2009204025A1 (en) | 2009-07-16 |
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