ZA201001621B - Heterocycle-substituted piperazino-dihydrothienopyrimidines - Google Patents

Heterocycle-substituted piperazino-dihydrothienopyrimidines

Info

Publication number
ZA201001621B
ZA201001621B ZA201001621A ZA201001621A ZA201001621B ZA 201001621 B ZA201001621 B ZA 201001621B ZA 201001621 A ZA201001621 A ZA 201001621A ZA 201001621 A ZA201001621 A ZA 201001621A ZA 201001621 B ZA201001621 B ZA 201001621B
Authority
ZA
South Africa
Prior art keywords
dihydrothienopyrimidines
heterocycle
substituted piperazino
piperazino
substituted
Prior art date
Application number
ZA201001621A
Other languages
English (en)
Inventor
Pascale Pouzet
Horst Dollinger
Thomas Fox
Christoph Hoenke
Peter Nickolaus
Ralf Anderskewitz
Dennis Fiegen
Rolf Goeggel
Domnic Martyres
Klaus Klinder
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of ZA201001621B publication Critical patent/ZA201001621B/xx

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA201001621A 2007-10-19 2010-03-05 Heterocycle-substituted piperazino-dihydrothienopyrimidines ZA201001621B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07118911 2007-10-19

Publications (1)

Publication Number Publication Date
ZA201001621B true ZA201001621B (en) 2010-10-27

Family

ID=39204738

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA201001621A ZA201001621B (en) 2007-10-19 2010-03-05 Heterocycle-substituted piperazino-dihydrothienopyrimidines

Country Status (18)

Country Link
US (2) US8637519B2 (es)
EP (1) EP2205609B1 (es)
JP (1) JP5341899B2 (es)
KR (1) KR20100075930A (es)
CN (1) CN101827853A (es)
AR (1) AR069076A1 (es)
AU (1) AU2008313742B2 (es)
BR (1) BRPI0817781A2 (es)
CA (1) CA2702524A1 (es)
CL (1) CL2008003097A1 (es)
MX (1) MX2010003346A (es)
NZ (1) NZ585348A (es)
PE (1) PE20091081A1 (es)
RU (1) RU2500681C2 (es)
TW (1) TWI445535B (es)
UY (1) UY31402A1 (es)
WO (1) WO2009050242A2 (es)
ZA (1) ZA201001621B (es)

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CN113880859B (zh) * 2021-11-16 2022-06-21 江西科技师范大学 2-芳基-4-芳甲胺基嘧啶类化合物及其应用
TW202339731A (zh) 2021-12-09 2023-10-16 德商百靈佳殷格翰國際股份有限公司 用於治療進行性纖維化間質性肺病之新穎口服醫藥組合物及劑量療法
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EP2205609A2 (de) 2010-07-14
AR069076A1 (es) 2009-12-30
CL2008003097A1 (es) 2010-01-22
RU2010119645A (ru) 2012-01-27
TWI445535B (zh) 2014-07-21
AU2008313742B2 (en) 2013-11-28
US20140107103A1 (en) 2014-04-17
BRPI0817781A2 (pt) 2019-09-24
RU2500681C2 (ru) 2013-12-10
US9115142B2 (en) 2015-08-25
JP2011500639A (ja) 2011-01-06
UY31402A1 (es) 2009-05-29
KR20100075930A (ko) 2010-07-05
US20100305102A1 (en) 2010-12-02
TW200918073A (en) 2009-05-01
PE20091081A1 (es) 2009-08-24
MX2010003346A (es) 2010-04-09
JP5341899B2 (ja) 2013-11-13
CA2702524A1 (en) 2009-04-23
WO2009050242A3 (de) 2009-07-30
CN101827853A (zh) 2010-09-08
AU2008313742A1 (en) 2009-04-23
NZ585348A (en) 2012-02-24
EP2205609B1 (de) 2017-03-29
US8637519B2 (en) 2014-01-28
WO2009050242A2 (de) 2009-04-23

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