ZA201000843B - Crystalline form of methyl((1s)-1-(((2s)-2-(5-(4'-2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1h-imidazol-5-yl)-4-biphenylyl)-1h-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt - Google Patents

Crystalline form of methyl((1s)-1-(((2s)-2-(5-(4'-2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1h-imidazol-5-yl)-4-biphenylyl)-1h-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt

Info

Publication number
ZA201000843B
ZA201000843B ZA2010/00843A ZA201000843A ZA201000843B ZA 201000843 B ZA201000843 B ZA 201000843B ZA 2010/00843 A ZA2010/00843 A ZA 2010/00843A ZA 201000843 A ZA201000843 A ZA 201000843A ZA 201000843 B ZA201000843 B ZA 201000843B
Authority
ZA
South Africa
Prior art keywords
imidazol
pyrrolidinyl
methylbutanoyl
biphenylyl
methylpropyl
Prior art date
Application number
ZA2010/00843A
Other languages
English (en)
Inventor
Fukang Yang
Qi Gao
Soojin Kim
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39739413&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA201000843(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of ZA201000843B publication Critical patent/ZA201000843B/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA2010/00843A 2007-08-08 2010-02-04 Crystalline form of methyl((1s)-1-(((2s)-2-(5-(4'-2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1h-imidazol-5-yl)-4-biphenylyl)-1h-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt ZA201000843B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95459207P 2007-08-08 2007-08-08
PCT/US2008/071734 WO2009020828A1 (en) 2007-08-08 2008-07-31 Crystalline form of methyl ((1s)-1-(((2s)-2-(5-(4'-(2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1h-imidazol-5-yl)-4-biphenylyl)-1h-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt

Publications (1)

Publication Number Publication Date
ZA201000843B true ZA201000843B (en) 2011-04-28

Family

ID=39739413

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2010/00843A ZA201000843B (en) 2007-08-08 2010-02-04 Crystalline form of methyl((1s)-1-(((2s)-2-(5-(4'-2-((2s)-1-((2s)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1h-imidazol-5-yl)-4-biphenylyl)-1h-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt

Country Status (20)

Country Link
US (1) US8629171B2 (cg-RX-API-DMAC10.html)
EP (1) EP2183244B1 (cg-RX-API-DMAC10.html)
JP (1) JP5244179B2 (cg-RX-API-DMAC10.html)
KR (1) KR101508022B1 (cg-RX-API-DMAC10.html)
CN (1) CN101778840B (cg-RX-API-DMAC10.html)
AR (2) AR070016A1 (cg-RX-API-DMAC10.html)
AU (1) AU2008284100B2 (cg-RX-API-DMAC10.html)
BR (1) BRPI0815142B8 (cg-RX-API-DMAC10.html)
CA (1) CA2695729C (cg-RX-API-DMAC10.html)
CL (1) CL2008002354A1 (cg-RX-API-DMAC10.html)
CO (1) CO6160327A2 (cg-RX-API-DMAC10.html)
EA (1) EA018152B1 (cg-RX-API-DMAC10.html)
ES (1) ES2402791T3 (cg-RX-API-DMAC10.html)
IL (1) IL203684A (cg-RX-API-DMAC10.html)
MX (1) MX2010001368A (cg-RX-API-DMAC10.html)
NZ (1) NZ583148A (cg-RX-API-DMAC10.html)
PE (1) PE20090940A1 (cg-RX-API-DMAC10.html)
TW (1) TWI359813B (cg-RX-API-DMAC10.html)
WO (1) WO2009020828A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201000843B (cg-RX-API-DMAC10.html)

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