ZA201000318B - Inhibitors of 11b-hydroxysteroid dehydrogenase - Google Patents

Inhibitors of 11b-hydroxysteroid dehydrogenase

Info

Publication number
ZA201000318B
ZA201000318B ZA201000318A ZA201000318A ZA201000318B ZA 201000318 B ZA201000318 B ZA 201000318B ZA 201000318 A ZA201000318 A ZA 201000318A ZA 201000318 A ZA201000318 A ZA 201000318A ZA 201000318 B ZA201000318 B ZA 201000318B
Authority
ZA
South Africa
Prior art keywords
inhibitors
hydroxysteroid dehydrogenase
hydroxysteroid
dehydrogenase
Prior art date
Application number
ZA201000318A
Other languages
English (en)
Inventor
Paul Gillespie
Kevin Richard Guertin
Lida Qi
Qiang Zhang
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA201000318B publication Critical patent/ZA201000318B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA201000318A 2007-07-17 2010-01-15 Inhibitors of 11b-hydroxysteroid dehydrogenase ZA201000318B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US95016807P 2007-07-17 2007-07-17

Publications (1)

Publication Number Publication Date
ZA201000318B true ZA201000318B (en) 2010-10-27

Family

ID=40019292

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA201000318A ZA201000318B (en) 2007-07-17 2010-01-15 Inhibitors of 11b-hydroxysteroid dehydrogenase

Country Status (16)

Country Link
US (1) US7790711B2 (es)
EP (1) EP2178845B1 (es)
JP (1) JP5189165B2 (es)
KR (1) KR101158191B1 (es)
CN (1) CN101743226B (es)
AR (1) AR067538A1 (es)
AU (1) AU2008277783B2 (es)
BR (1) BRPI0814825A2 (es)
CA (1) CA2693457C (es)
CL (1) CL2008002052A1 (es)
ES (1) ES2423181T3 (es)
PE (1) PE20090813A1 (es)
RU (1) RU2440989C2 (es)
TW (1) TWI372623B (es)
WO (1) WO2009010416A2 (es)
ZA (1) ZA201000318B (es)

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Also Published As

Publication number Publication date
CN101743226A (zh) 2010-06-16
US7790711B2 (en) 2010-09-07
KR101158191B1 (ko) 2012-06-19
EP2178845B1 (en) 2013-06-19
CN101743226B (zh) 2012-10-10
AU2008277783B2 (en) 2012-09-20
RU2440989C2 (ru) 2012-01-27
TW200913992A (en) 2009-04-01
WO2009010416A2 (en) 2009-01-22
AU2008277783A1 (en) 2009-01-22
PE20090813A1 (es) 2009-06-27
ES2423181T3 (es) 2013-09-18
WO2009010416A3 (en) 2009-03-05
CA2693457A1 (en) 2009-01-22
BRPI0814825A2 (pt) 2015-02-03
RU2010105299A (ru) 2011-08-27
JP2010533670A (ja) 2010-10-28
CL2008002052A1 (es) 2009-05-22
JP5189165B2 (ja) 2013-04-24
KR20100034763A (ko) 2010-04-01
AR067538A1 (es) 2009-10-14
EP2178845A2 (en) 2010-04-28
TWI372623B (en) 2012-09-21
US20090023709A1 (en) 2009-01-22
CA2693457C (en) 2012-10-23

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