ZA200902902B - Controlled release delivery system for nasal application of neurotransmitters - Google Patents

Controlled release delivery system for nasal application of neurotransmitters

Info

Publication number
ZA200902902B
ZA200902902B ZA200902902A ZA200902902A ZA200902902B ZA 200902902 B ZA200902902 B ZA 200902902B ZA 200902902 A ZA200902902 A ZA 200902902A ZA 200902902 A ZA200902902 A ZA 200902902A ZA 200902902 B ZA200902902 B ZA 200902902B
Authority
ZA
South Africa
Prior art keywords
neurotransmitters
delivery system
controlled release
release delivery
nasal application
Prior art date
Application number
ZA200902902A
Other languages
English (en)
Inventor
Claudia Mattern
Original Assignee
M & P Patent Aktinegesellschaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by M & P Patent Aktinegesellschaf filed Critical M & P Patent Aktinegesellschaf
Publication of ZA200902902B publication Critical patent/ZA200902902B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
ZA200902902A 2006-10-04 2007-09-27 Controlled release delivery system for nasal application of neurotransmitters ZA200902902B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82810906P 2006-10-04 2006-10-04

Publications (1)

Publication Number Publication Date
ZA200902902B true ZA200902902B (en) 2010-07-28

Family

ID=38799348

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200902902A ZA200902902B (en) 2006-10-04 2007-09-27 Controlled release delivery system for nasal application of neurotransmitters

Country Status (20)

Country Link
US (4) US20090227550A1 (es)
EP (1) EP2068825B1 (es)
JP (1) JP5248510B2 (es)
KR (1) KR101307133B1 (es)
CN (1) CN101600417B (es)
AT (1) ATE496617T1 (es)
AU (1) AU2007304471B2 (es)
BR (1) BRPI0717509B8 (es)
CA (1) CA2664427C (es)
DE (1) DE602007012276D1 (es)
DK (1) DK2068825T3 (es)
ES (1) ES2358619T3 (es)
HK (1) HK1137658A1 (es)
MX (1) MX2009003654A (es)
NO (1) NO339802B1 (es)
PL (1) PL2068825T3 (es)
PT (1) PT2068825E (es)
RU (1) RU2480208C2 (es)
WO (1) WO2008040488A1 (es)
ZA (1) ZA200902902B (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8784869B2 (en) 2003-11-11 2014-07-22 Mattern Pharma Ag Controlled release delivery system for nasal applications and methods of treatment
DE60303854T2 (de) 2003-11-11 2006-08-10 Mattern, Udo Nasenformulierung mit kontrollierter Freisetzung von Sexualhormonen
US20060140820A1 (en) 2004-12-28 2006-06-29 Udo Mattern Use of a container of an inorganic additive containing plastic material
PL2068825T3 (pl) 2006-10-04 2011-06-30 M & P Patent Ag Układ dostarczania o kontrolowanym uwalnianiu do donosowego podawania związków neuroprzekaźnikowych
US9757388B2 (en) 2011-05-13 2017-09-12 Acerus Pharmaceuticals Srl Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels
US20130045958A1 (en) 2011-05-13 2013-02-21 Trimel Pharmaceuticals Corporation Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder
US20130040923A1 (en) 2011-05-13 2013-02-14 Trimel Pharmaceuticals Corporation Intranasal lower dosage strength testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder
KR20140033407A (ko) 2011-05-13 2014-03-18 트리멜 바이오파마 에스알엘 비강내 저 용량 강도 테스토스테론 겔 제형 및 성불감증 또는 성욕 감퇴 장애를 치료하기 위한 이의 용도
CN110613679A (zh) * 2011-05-15 2019-12-27 埃瑟尔斯生物医药有限公司 控释鼻腔睾酮凝胶、用于经鼻给药的方法和预充式多剂量施药器系统
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
PT2782584T (pt) 2011-11-23 2021-09-02 Therapeuticsmd Inc Preparações e terapias de substituição para hormonoterapias naturais combinadas
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
DE102012015248A1 (de) * 2012-08-05 2014-02-06 Naum Goldstein Verfahren zur Einbringung biologisch aktiver Substanzen ins Gehirn
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11744838B2 (en) 2013-03-15 2023-09-05 Acerus Biopharma Inc. Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
WO2016013298A1 (ja) * 2014-07-25 2016-01-28 日本電気株式会社 画像処理装置、監視システム、画像処理方法、及びプログラム
BR112016029338A2 (pt) 2014-07-29 2017-08-22 Therapeuticsmd Inc creme transdérmico
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
CA3020153A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
SG11201810628XA (en) * 2016-06-03 2018-12-28 M et P Pharma AG Nasal pharmaceutical compositions with a porous excipient
CN110461340A (zh) * 2017-01-20 2019-11-15 马特恩制药股份公司 用于降低暴露于空气污染物的风险的鼻用药物组合物
CA3087840A1 (en) 2018-01-11 2019-07-18 M et P Pharma AG Treatment of demyelinating diseases
WO2019148140A2 (en) * 2018-01-26 2019-08-01 Wu Joseph C Implantable biomaterials that enhance stem cell survival and function
AU2019253577A1 (en) 2018-04-09 2019-12-12 Elgan Pharma Ltd Oxytocin compositions and methods of use
AU2019256828A1 (en) * 2018-04-17 2020-12-03 M et P Pharma AG Compositions and methods for intranasal delivery of pregnenolone

Family Cites Families (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE943792C (de) 1949-02-18 1956-06-01 Organon Nv Verfahren zur Herstellung von injizierbaren Hormonpraeparaten
GB1032874A (en) 1964-02-13 1966-06-15 Du Pont Stabilized polyoxymethylenes
US3769424A (en) 1970-10-01 1973-10-30 Merck & Co Inc Composition and method of treating dopamine deficiency in brain tissue
US4123417A (en) 1974-10-10 1978-10-31 Mobil Oil Corporation Low density polyethylene toughened with ethylene/propylene copolymer
NL7506407A (nl) 1975-05-30 1976-12-02 Akzo Nv Werkwijze ter bereiding van een oraal werkzaam far- maceutisch preparaat.
NL7510104A (nl) 1975-08-27 1977-03-01 Akzo Nv Werkwijze ter bereiding van een oraal werkzaam farmaceutisch preparaat.
DE2548413A1 (de) 1975-10-27 1977-04-28 Schering Ag Depotpraeparate in oeliger ungesaettigter loesung zur intramuskulaeren injektion
US4315925A (en) 1980-05-30 1982-02-16 University Of Kentucky Research Foundation Method of administering natural female sex hormones
DE3151912A1 (de) 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
US4546882A (en) 1983-02-07 1985-10-15 American Can Company Package having oil-containing product
US4581255A (en) * 1983-08-30 1986-04-08 Abitibi-Price Corporation Method of making simulated ceramic tile
JPS60136283U (ja) 1984-02-22 1985-09-10 株式会社シマノ キヤリバ−ブレ−キ
ZA852884B (en) * 1984-04-25 1986-11-26 Lilly Co Eli Sustained release intranasal formulation and method of use thereof
US4581225A (en) * 1984-04-25 1986-04-08 Eli Lilly And Company Sustained release intranasal formulation and method of use thereof
US4812448A (en) 1984-10-22 1989-03-14 Knepper Paul A Method for the prevention of ocular hypertension, treatment of glaucoma and treatment of ocular hypertension
US4752425A (en) 1986-09-18 1988-06-21 Liposome Technology, Inc. High-encapsulation liposome processing method
US4786678A (en) 1986-12-29 1988-11-22 Mobil Oil Corporation Method of producing films from polyethylene resin, an additive and a second polymeric resin
US5049387A (en) 1987-03-09 1991-09-17 Alza Corporation Inducing skin tolerance to a sensitizing drug
US5690954A (en) 1987-05-22 1997-11-25 Danbiosyst Uk Limited Enhanced uptake drug delivery system having microspheres containing an active drug and a bioavailability improving material
JPS646716A (en) 1987-06-27 1989-01-11 Suzuki Motor Co Displacement measuring apparatus
JP2543708B2 (ja) 1987-07-13 1996-10-16 旭化成工業株式会社 難溶性薬物を封入したエマルジョン製剤の製造方法
JPH01160916A (ja) * 1987-12-18 1989-06-23 Tanabe Seiyaku Co Ltd ドーパミン経鼻投与製剤
NL8801670A (nl) 1988-07-01 1990-02-01 Walter Adrianus Josephus Johan Farmaceutisch preparaat.
GB2237510B (en) 1989-11-04 1993-09-15 Danbiosyst Uk Small particle drug compositions for nasal administration
US5397771A (en) 1990-05-10 1995-03-14 Bechgaard International Research And Development A/S Pharmaceutical preparation
US5624960A (en) * 1991-01-23 1997-04-29 Isis Pharma Gmbh Orally administrable drugs for the treatment of central dopamine deficiency conditions
US5500261A (en) 1991-05-24 1996-03-19 Kao Corporation Resin composition and a container
US5221698A (en) 1991-06-27 1993-06-22 The Regents Of The University Of Michigan Bioactive composition
US5756071A (en) 1992-06-03 1998-05-26 Arrowdean Limited Method for nasally administering aerosols of therapeutic agents to enhance penetration of the blood brain barrier
DE4218291A1 (de) 1992-06-03 1993-12-09 Mattern Et Partner Pharmazeuti Dosierspray für pernasale Applikation
SE9301171D0 (sv) 1993-04-07 1993-04-07 Ab Astra Pharmaceutical composition containing lipophilic drugs
AU691250B2 (en) 1994-02-04 1998-05-14 Lipocore Holding Ab Lipophilic carrier preparations
GB9405304D0 (en) 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
US5635203A (en) 1994-09-29 1997-06-03 Alza Corporation Transdermal device having decreased delamination
DE69524614T2 (de) 1994-10-05 2002-09-12 Hisamitsu Pharmaceutical Co Arzneimittelbestandteile einschliesslich eines n-substituierten o-toluidinderivats und transdermal absorbierbare zubereitung
US5747058A (en) 1995-06-07 1998-05-05 Southern Biosystems, Inc. High viscosity liquid controlled delivery system
GB9608719D0 (en) 1996-04-26 1996-07-03 Scherer Ltd R P Pharmaceutical compositions
GB9707934D0 (en) 1997-04-18 1997-06-04 Danbiosyst Uk Improved delivery of drugs to mucosal surfaces
US6624200B2 (en) 1998-08-25 2003-09-23 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US5877216A (en) 1997-10-28 1999-03-02 Vivus, Incorporated Treatment of female sexual dysfunction
US5897894A (en) 1997-12-29 1999-04-27 General Mills, Inc. Microwave popcorn with coarse salt crystals and method of preparation
AU3843999A (en) * 1998-05-07 1999-11-23 Elan Corporation, Plc Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems
FR2779438B1 (fr) 1998-06-03 2004-12-24 Jean Marc Aiache Gel stable, son procede de preparation, et compositions pharmaceutiques le comprenant
GB9823246D0 (en) 1998-10-24 1998-12-16 Danbiosyst Uk A nasal drug delivery composition
US6838091B2 (en) * 1998-12-18 2005-01-04 Abbott Laboratories Formulations comprising lipid-regulating agents
US6319905B1 (en) * 1998-12-29 2001-11-20 Cell Genesys, Inc. Method of controlling L-Dopa production and of treating dopamine deficiency
GB9828861D0 (en) 1998-12-31 1999-02-17 Danbiosyst Uk Compositions
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US6294192B1 (en) 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6761903B2 (en) 1999-06-30 2004-07-13 Lipocine, Inc. Clear oil-containing pharmaceutical compositions containing a therapeutic agent
EP1189620B1 (en) 1999-04-01 2004-06-23 Akzo Nobel N.V. Formulation comprising testosteron undecanoate and castor oil
US6287588B1 (en) 1999-04-29 2001-09-11 Macromed, Inc. Agent delivering system comprised of microparticle and biodegradable gel with an improved releasing profile and methods of use thereof
CO5180583A1 (es) 1999-06-11 2002-07-30 Watson Pharmaceuticals Inc Administracion de esteroides androgenicos no orales a las mujeres
KR100801588B1 (ko) 1999-09-21 2008-02-05 스키에파마 캐나다 인코포레이티드 생물학적 유효 물질의 표면 변형된 미립자 조성물
US6720001B2 (en) 1999-10-18 2004-04-13 Lipocine, Inc. Emulsion compositions for polyfunctional active ingredients
US6231662B1 (en) 1999-10-25 2001-05-15 George K. Atkinson Surface treatments for titanium dioxide and other industrial pigments
AU1261501A (en) 1999-12-06 2001-06-18 Stanley L. Gore Compositions and methods for intranasal delivery of active agents to the brain
US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
US20030139384A1 (en) 2000-08-30 2003-07-24 Dudley Robert E. Method for treating erectile dysfunction and increasing libido in men
US20020072509A1 (en) 2000-10-11 2002-06-13 Stein Donald Gerald Methods for the treatment of a traumatic central nervous system injury
TW586946B (en) 2000-12-22 2004-05-11 Novartis Ag Process to improve stability
US20020114933A1 (en) 2000-12-28 2002-08-22 Gould Richard J. Grease masking packaging materials and methods thereof
US6730330B2 (en) 2001-02-14 2004-05-04 Gw Pharma Limited Pharmaceutical formulations
KR20040052489A (ko) 2001-03-06 2004-06-23 셀러지 파마세우티칼스, 인크 비뇨생식기 장애 치료용 화합물 및 그 방법
US20040028613A1 (en) * 2001-06-25 2004-02-12 Nastech Pharmaceutical Company Inc Dopamine agonist formulations for enhanced central nervous system delivery
US6833478B2 (en) * 2001-07-13 2004-12-21 Sri International N,N-dinitramide salts as solubilizing agents for biologically active agents
US6800363B2 (en) 2001-08-30 2004-10-05 Toray Plastics, Inc. Polyolefin oil resistant film using porous particles
US6815506B2 (en) 2001-10-15 2004-11-09 Jsr Corporation Oil-resistant thermoplastic elastomer composition and moldings using the same
BR0307344A (pt) 2002-02-01 2004-12-14 Pfizer Prod Inc Composições farmacêuticas de dispersões amorfas de fármacos e materiais formadores de microfase lipofìlica
US6855332B2 (en) 2002-07-03 2005-02-15 Lyfjathroun Hf. Absorption promoting agent
US6958142B2 (en) 2002-08-02 2005-10-25 Balance Pharmaceuticals, Inc. Nasal spray formulation and method
US7029657B2 (en) 2002-08-02 2006-04-18 Balance Pharmaceuticals, Inc. Nasal spray steroid formulation and method
US20040259852A1 (en) 2003-06-18 2004-12-23 White Hillary D. Trandsdermal compositions and methods for treatment of fibromyalgia and chronic fatigue syndrome
DE60303854T2 (de) 2003-11-11 2006-08-10 Mattern, Udo Nasenformulierung mit kontrollierter Freisetzung von Sexualhormonen
US8784869B2 (en) 2003-11-11 2014-07-22 Mattern Pharma Ag Controlled release delivery system for nasal applications and methods of treatment
CA2550811C (en) 2003-12-24 2012-05-01 Jane Hirsh Temperature-stable formulations, and methods of development thereof
US20060140820A1 (en) 2004-12-28 2006-06-29 Udo Mattern Use of a container of an inorganic additive containing plastic material
EP1957113A4 (en) * 2005-11-21 2011-11-09 Medivas Llc POLYMER PARTICLES FOR THE OUTPUT OF MACROMOLECULES AND METHOD OF APPLICATION THEREFOR
PL2068825T3 (pl) 2006-10-04 2011-06-30 M & P Patent Ag Układ dostarczania o kontrolowanym uwalnianiu do donosowego podawania związków neuroprzekaźnikowych

Also Published As

Publication number Publication date
BRPI0717509A2 (pt) 2016-05-17
US9186320B2 (en) 2015-11-17
BRPI0717509B1 (pt) 2019-11-26
JP2010505778A (ja) 2010-02-25
US20120009249A1 (en) 2012-01-12
KR20090098958A (ko) 2009-09-18
DE602007012276D1 (de) 2011-03-10
ES2358619T3 (es) 2011-05-12
AU2007304471B2 (en) 2012-09-06
WO2008040488A1 (en) 2008-04-10
CN101600417B (zh) 2012-05-30
EP2068825B1 (en) 2011-01-26
BRPI0717509B8 (pt) 2021-05-25
RU2009116609A (ru) 2010-11-10
KR101307133B1 (ko) 2013-09-12
MX2009003654A (es) 2009-04-22
US20090227550A1 (en) 2009-09-10
ATE496617T1 (de) 2011-02-15
CA2664427A1 (en) 2008-04-10
DK2068825T3 (da) 2011-05-16
US20180200203A1 (en) 2018-07-19
PL2068825T3 (pl) 2011-06-30
US9801834B2 (en) 2017-10-31
NO339802B1 (no) 2017-02-06
CN101600417A (zh) 2009-12-09
PT2068825E (pt) 2011-02-11
NO20091695L (no) 2009-06-23
HK1137658A1 (en) 2010-08-06
JP5248510B2 (ja) 2013-07-31
US20160089347A1 (en) 2016-03-31
EP2068825A1 (en) 2009-06-17
RU2480208C2 (ru) 2013-04-27
CA2664427C (en) 2012-06-05
AU2007304471A1 (en) 2008-04-10

Similar Documents

Publication Publication Date Title
HK1137658A1 (en) Controlled release delivery system for nasal application of neurotransmitters
MX2019003467A (es) Formulaciones y metodos para la administracion vaginal de antiprogestinas.
PH12015501595A1 (en) Spiro-lactam nmda receptor modulators and uses thereof
PH12015501598A1 (en) Spiro-lactam nmda receptor modulators and uses thereof
AU2008347158A8 (en) Oral pharmaceutical dosage forms
MX2009010289A (es) Composiciones para administracion nasal.
PH12015501600A1 (en) Spiro-lactam nmda receptor modulators and uses thereof
MY131483A (en) Controlled release delivery system of sexual hormones for nasal applications
WO2006124047A3 (en) Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent
MX363495B (es) Proceso de manufacturacion de una forma de dosificacion multifasica de rapida disolucion liofilizada.
NZ605352A (en) Process for producing glycosaminoglycans
MX2010003923A (es) Formulacion farmaceutica de valsartan.
MX353623B (es) Sistema de suministro de farmaco.
CL2011002807A1 (es) Mezcla farmaceutica comprimible que comprende cristales de un farmaco con tamaño de particulas inferior a 40 um y un adyuvante de la disolucion; procedimiento para preparar un vehiculo de administracion para un farmaco que incluye moler una premezcla de cristales de farmaco y un adyuvante de la disolucion.
MX2017013636A (es) Combinacion de dosis fija resistente a la manipulacion que proporciona una liberacion rapida de dos farmacos desde diferentes particulas.
MD4591B1 (ro) Dispersie solidă a unui modulator selectiv al receptorului de progesteron
WO2009076413A3 (en) Methods, devices and compositions for controlled drug delivery to injured myocardium
MY166972A (en) Transdermal delivery system containing galantamine or salts thereof
MX2017013633A (es) Combinacion de dosis fija resistente a la manipulacion que proporciona una liberacion rapida de dos farmacos desde particulas.
MX2017013643A (es) Combinacion de dosis fija resistente a la manipulacion que proporciona una liberacion rapida de dos farmacos desde particulas y una matriz.
MX2020006886A (es) Sistema para suministro de medicamento.
IN2014CN02343A (en) Oral formulations containing hyaluronic acid for sustained drug release
EA201992463A1 (ru) Система доставки лекарственного средства
UA78605U (en) Pharmaceutical composition