ZA200804762B - 1,3-oxazolidin-2-one derivatives useful as CETP inhibitors - Google Patents
1,3-oxazolidin-2-one derivatives useful as CETP inhibitorsInfo
- Publication number
- ZA200804762B ZA200804762B ZA200804762A ZA200804762A ZA200804762B ZA 200804762 B ZA200804762 B ZA 200804762B ZA 200804762 A ZA200804762 A ZA 200804762A ZA 200804762 A ZA200804762 A ZA 200804762A ZA 200804762 B ZA200804762 B ZA 200804762B
- Authority
- ZA
- South Africa
- Prior art keywords
- oxazolidin
- derivatives useful
- cetp inhibitors
- cetp
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75528405P | 2005-12-30 | 2005-12-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200804762B true ZA200804762B (en) | 2009-04-29 |
Family
ID=38110277
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200804762A ZA200804762B (en) | 2005-12-30 | 2008-06-02 | 1,3-oxazolidin-2-one derivatives useful as CETP inhibitors |
Country Status (14)
Country | Link |
---|---|
US (2) | US7915271B2 (fr) |
EP (1) | EP2029560B1 (fr) |
JP (1) | JP5040036B2 (fr) |
KR (2) | KR20140107671A (fr) |
CN (1) | CN101365689A (fr) |
AU (1) | AU2006332681B2 (fr) |
BR (1) | BRPI0620752A2 (fr) |
CA (1) | CA2635262C (fr) |
IL (1) | IL192102A0 (fr) |
NO (1) | NO20083334L (fr) |
NZ (1) | NZ568904A (fr) |
RU (1) | RU2513107C2 (fr) |
WO (1) | WO2007079186A2 (fr) |
ZA (1) | ZA200804762B (fr) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DOP2005000123A (es) | 2004-07-02 | 2011-07-15 | Merck Sharp & Dohme | Inhibidores de cetp |
WO2007081569A2 (fr) * | 2005-12-30 | 2007-07-19 | Merck & Co., Inc. | Inhibiteurs de cetp |
WO2008082567A1 (fr) * | 2006-12-29 | 2008-07-10 | Merck & Co., Inc. | Procédé de synthèse d'un inhibiteur de la cetp |
CA2678577A1 (fr) | 2007-02-26 | 2008-09-04 | Vitae Pharmaceuticals, Inc. | Inhibiteurs d'uree et de carbamate de 11b-hydroxysteroide deshydrogenase 1 cycliques |
CN103450077B (zh) | 2007-06-08 | 2016-07-06 | 满康德股份有限公司 | IRE-1α抑制剂 |
JP5451611B2 (ja) | 2007-07-26 | 2014-03-26 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1のサイクリックインヒビター |
WO2009027785A2 (fr) * | 2007-08-30 | 2009-03-05 | Pfizer Products Inc. | Composés pharmaceutiques et dérivés |
CN101412711A (zh) * | 2007-10-15 | 2009-04-22 | 上海恒瑞医药有限公司 | 氨基甲酸酯类衍生物及其在医药上的应用 |
AR069207A1 (es) | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1 |
EP2222638A2 (fr) * | 2007-11-21 | 2010-09-01 | Decode Genetics EHF | Inhibiteurs de pde4 biaryle pour traiter une inflammation |
JP2011504505A (ja) | 2007-11-21 | 2011-02-10 | デコード ジェネティクス イーエイチエフ | 肺および心血管障害を治療するためのビアリールpde4抑制剤 |
US8440658B2 (en) | 2007-12-11 | 2013-05-14 | Vitae Pharmaceuticals, Inc. | Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
CA2712500A1 (fr) | 2008-01-24 | 2009-07-30 | Vitae Pharmaceuticals, Inc. | Carbazate cyclique et inhibiteurs du type semi-carbazide de la 11beta-hydroxysteroide deshydrogenase 1 |
EP2252598A2 (fr) | 2008-02-11 | 2010-11-24 | Vitae Pharmaceuticals, Inc. | Inhibiteurs 1,3-oxazepan-2-one et 1,3-diazepan-2-one de la 11 -hydroxystéroïde déshydrogénase (type1) |
JP5730021B2 (ja) | 2008-02-15 | 2015-06-03 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤としてのシクロアルキルラクタム誘導体 |
WO2009108720A2 (fr) | 2008-02-25 | 2009-09-03 | Amira Pharmaceuticals, Inc. | Antagonistes des récepteurs d2 de la prostaglandine |
EP2300461B1 (fr) | 2008-05-01 | 2013-04-17 | Vitae Pharmaceuticals, Inc. | Inhibiteurs cycliques de la 11-bêta-hydroxystéroïde déhydrogénase 1 |
EP2291371B1 (fr) | 2008-05-01 | 2015-06-10 | Vitae Pharmaceuticals, Inc. | Inhibiteurs cycliques de la 11-bêta-hydroxystéroïde déhydrogénase 1 |
JP5451752B2 (ja) | 2008-05-01 | 2014-03-26 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状インヒビター |
JP5538365B2 (ja) | 2008-05-01 | 2014-07-02 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状阻害剤 |
EP2687525B1 (fr) | 2008-07-25 | 2015-09-23 | Boehringer Ingelheim International GmbH | Inhibiteurs cycliques de la 11-bêta-hydroxystéroïde déshydrogénase 1 |
WO2010010157A2 (fr) | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | Inhibiteurs de la 11 bêta-hydroxystéroïde déshydrogénase 1 |
WO2010039474A1 (fr) * | 2008-10-01 | 2010-04-08 | Merck Sharp & Dohme Corp. | Promédicaments d'inhibiteurs de cetp à base d'oxazolidinone |
WO2010039977A2 (fr) | 2008-10-01 | 2010-04-08 | Amira Pharmaceuticals, Inc. | Antagonistes d’hétéroaryle des récepteurs de la prostaglandine d2 |
JP5679997B2 (ja) | 2009-02-04 | 2015-03-04 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状阻害剤 |
MA33216B1 (fr) | 2009-04-30 | 2012-04-02 | Boehringer Ingelheim Int | Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1 |
US8927539B2 (en) | 2009-06-11 | 2015-01-06 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure |
US8883778B2 (en) | 2009-07-01 | 2014-11-11 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1 |
CN102030770B (zh) * | 2009-09-25 | 2012-10-31 | 北京大学 | 一种芳香硼酸酯化合物的制备方法 |
NZ599549A (en) * | 2009-10-26 | 2013-11-29 | Signal Pharm Llc | Methods of synthesis and purification of heteroaryl compounds |
JP5860042B2 (ja) | 2010-06-16 | 2016-02-16 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 置換5、6及び7員複素環、そのような化合物を含有する医薬及びそれらの使用 |
EP2585444B1 (fr) | 2010-06-25 | 2014-10-22 | Boehringer Ingelheim International GmbH | Azaspirohexanones comme inhibiteurs de 11-beta -hsd1 pour le traitement de troubles métaboliques |
CA2814846A1 (fr) * | 2010-10-29 | 2012-05-03 | Merck Sharp & Dohme Corp. | Inhibiteur de cetp substitue par des amines cycliques a base d'oxazolidinone |
CA2813671A1 (fr) | 2010-11-02 | 2012-05-10 | Boehringer Ingelheim International Gmbh | Combinaisons pharmaceutiques destinees au traitement de troubles du metabolisme |
WO2012101142A1 (fr) | 2011-01-26 | 2012-08-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Méthode d'évaluation du risque d'un sujet de contracter une maladie cardiovasculaire |
MX342104B (es) | 2011-04-12 | 2016-09-13 | Chong Kun Dang Pharmaceutical Corp | Derivados de cicloalquenil arilo para inhibidor de cetp. |
ES2683350T3 (es) | 2011-07-08 | 2018-09-26 | Novartis Ag | Método para tratar la aterosclerosis en sujetos con alto nivel de triglicéridos |
US9073881B2 (en) | 2011-09-23 | 2015-07-07 | Hoffmann-La Roche Inc. | Benzoic acid derivatives |
JO3210B1 (ar) | 2011-10-28 | 2018-03-08 | Merck Sharp & Dohme | مثبط منصهر لبروتين نقل الكوليسترليستير اوكسازوليدينون ثمائي الحلقة |
CA2857164A1 (fr) | 2011-11-30 | 2013-06-06 | Daewoong Pharmaceutical Co., Ltd. | Composition pharmaceutique pour prevenir ou traiter l'hypertriglyceridemie ou les maladies associees a l'hypertriglyceridemie |
CN102516237B (zh) * | 2011-12-05 | 2014-02-26 | 成都苑东药业有限公司 | 一种恶唑烷酮类化合物 |
EP2844252B1 (fr) | 2012-05-02 | 2016-11-30 | Merck Sharp & Dohme Corp. | Hétérocycliques substitués par une amine cyclique comme inhibiteurs de cetp |
MX2014014614A (es) | 2012-05-31 | 2015-02-12 | Phenex Pharmaceuticals Ag | Tiazoles sustituidos por carboxamida o sulfonamida y derivados relacionados como moduladores para el receptor nuclear huerfano ror [gamma). |
CN103958484B (zh) * | 2012-07-19 | 2015-11-25 | 上海恒瑞医药有限公司 | 噁唑烷酮类衍生物、其制备方法及其在医药上的应用 |
EP2934518B1 (fr) | 2012-12-19 | 2020-02-19 | Merck Sharp & Dohme Corp. | Inhibiteurs de la cetp spirocycliques |
WO2014099834A1 (fr) * | 2012-12-20 | 2014-06-26 | Merck Sharp & Dohme Corp. | Composés de thiazolidinone thérapeutiques |
CN105143193B (zh) * | 2013-01-31 | 2017-12-15 | 株式会社钟根堂 | 作为cetp抑制剂的联芳基或杂环联芳基取代的环己烯衍生化合物 |
CN103113193A (zh) * | 2013-03-05 | 2013-05-22 | 华东师范大学 | 一种2-氯-5-三氟甲基苄醇的合成方法 |
WO2015017302A2 (fr) | 2013-07-30 | 2015-02-05 | Merck Sharp & Dohme Corp. | Urées bicycliques et thiadiazolidine-1,1-dioxydes servant d'inhibiteurs de cetp |
EP3054945B1 (fr) | 2013-10-10 | 2018-08-15 | Merck Sharp & Dohme Corp. | Indolines 3,3'-disubstituées utilisées comme inhibiteurs de la protéine de transfert du cholestérol estérifié |
US9663534B2 (en) | 2013-12-17 | 2017-05-30 | Merck Sharp & Dohme Corp. | Fused bicyclic isoxazolines as inhibitors of cholesterol ester transfer protein |
CN103864831A (zh) * | 2014-02-14 | 2014-06-18 | 上海工程技术大学 | 一种芳烃硼酸酯类化合物及其合成方法 |
WO2016018729A1 (fr) | 2014-07-29 | 2016-02-04 | Merck Sharp & Dohme Corp. | Isoxazolines monocycliques utilisées comme inhibiteurs de la protéine de transfert des esters de cholestérol |
EP3322420B1 (fr) * | 2015-07-13 | 2021-12-29 | Merck Sharp & Dohme Corp. | Hétérocycles bicycliques en tant qu'inhibiteurs de la protéine de transfert des esters de cholestérol |
CN106083837B (zh) * | 2016-05-27 | 2018-08-31 | 浙江普洛得邦制药有限公司 | 一种噁唑烷酮类抗菌药物及其中间体的制备方法 |
WO2018016743A1 (fr) * | 2016-07-19 | 2018-01-25 | 재단법인 대구경북첨단의료산업진흥재단 | Composé dérivé d'oxazolidinone en tant qu'inhibiteur de cetp |
CN106749075A (zh) * | 2016-11-24 | 2017-05-31 | 山东新华制药股份有限公司 | 阿那曲波的恶唑烷酮中间体的晶型及其制备方法 |
JOP20180092A1 (ar) | 2017-10-13 | 2019-04-13 | Gilead Sciences Inc | مثبطات hiv بروتياز |
TW202104210A (zh) | 2019-04-17 | 2021-02-01 | 美商基利科學股份有限公司 | Hiv蛋白酶抑制劑 |
JP2022541058A (ja) | 2019-07-19 | 2022-09-21 | バイオシント アクチェンゲゼルシャフト | ニコチンアミドリボフラノシド塩の製造方法、ニコチンアミドリボフラノシド塩自体、およびその使用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU203330B (en) * | 1987-06-10 | 1991-07-29 | Pfizer | Process for producing oxazolidin-2-one derivatives and hypoglychemic pharmaceutical compositions containing them |
US5480899A (en) * | 1992-04-30 | 1996-01-02 | Taiho Pharmaceutical Co., Ltd. | Oxazolidine derivatives and pharmaceutically acceptable salts thereof |
DE19962924A1 (de) * | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
KR100951218B1 (ko) * | 2001-10-16 | 2010-04-05 | 메모리 파마슈티칼스 코포레이션 | 신경계 증후군의 치료를 위한 pde-4 억제제로서의4-(4-알콕시-3-히드록시페닐)-2-피롤리돈 유도체 |
US7160886B2 (en) * | 2003-03-03 | 2007-01-09 | Merck & Co., Inc. | Acylated piperazine derivatives as melanocortin-4 receptor agonists |
DOP2005000123A (es) * | 2004-07-02 | 2011-07-15 | Merck Sharp & Dohme | Inhibidores de cetp |
-
2006
- 2006-12-29 CA CA2635262A patent/CA2635262C/fr not_active Expired - Fee Related
- 2006-12-29 NZ NZ568904A patent/NZ568904A/en not_active IP Right Cessation
- 2006-12-29 EP EP06849136.4A patent/EP2029560B1/fr not_active Not-in-force
- 2006-12-29 JP JP2008548748A patent/JP5040036B2/ja not_active Expired - Fee Related
- 2006-12-29 RU RU2008131294/04A patent/RU2513107C2/ru not_active IP Right Cessation
- 2006-12-29 KR KR1020147021619A patent/KR20140107671A/ko not_active Application Discontinuation
- 2006-12-29 BR BRPI0620752-9A patent/BRPI0620752A2/pt not_active IP Right Cessation
- 2006-12-29 AU AU2006332681A patent/AU2006332681B2/en not_active Ceased
- 2006-12-29 WO PCT/US2006/049494 patent/WO2007079186A2/fr active Application Filing
- 2006-12-29 US US12/087,290 patent/US7915271B2/en active Active
- 2006-12-29 CN CNA2006800501386A patent/CN101365689A/zh active Pending
-
2008
- 2008-06-02 ZA ZA200804762A patent/ZA200804762B/xx unknown
- 2008-06-12 IL IL192102A patent/IL192102A0/en unknown
- 2008-07-29 NO NO20083334A patent/NO20083334L/no not_active Application Discontinuation
- 2008-07-30 KR KR1020087018858A patent/KR101473258B1/ko not_active IP Right Cessation
-
2011
- 2011-03-28 US US13/073,190 patent/US8440702B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
BRPI0620752A2 (pt) | 2011-11-22 |
NO20083334L (no) | 2008-08-12 |
US7915271B2 (en) | 2011-03-29 |
CA2635262C (fr) | 2011-08-16 |
CN101365689A (zh) | 2009-02-11 |
RU2513107C2 (ru) | 2014-04-20 |
EP2029560A2 (fr) | 2009-03-04 |
NZ568904A (en) | 2011-05-27 |
CA2635262A1 (fr) | 2007-07-12 |
RU2008131294A (ru) | 2010-02-10 |
KR20080086530A (ko) | 2008-09-25 |
JP2009522290A (ja) | 2009-06-11 |
AU2006332681A1 (en) | 2007-07-12 |
WO2007079186A3 (fr) | 2007-12-06 |
AU2006332681B2 (en) | 2011-04-07 |
KR20140107671A (ko) | 2014-09-04 |
EP2029560B1 (fr) | 2013-04-24 |
US20090137548A1 (en) | 2009-05-28 |
IL192102A0 (en) | 2008-12-29 |
KR101473258B1 (ko) | 2014-12-16 |
US20110178059A1 (en) | 2011-07-21 |
US8440702B2 (en) | 2013-05-14 |
JP5040036B2 (ja) | 2012-10-03 |
WO2007079186A2 (fr) | 2007-07-12 |
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