ZA200710113B - Nanoparticulate clopidogrel formulations - Google Patents

Nanoparticulate clopidogrel formulations

Info

Publication number
ZA200710113B
ZA200710113B ZA200710113A ZA200710113A ZA200710113B ZA 200710113 B ZA200710113 B ZA 200710113B ZA 200710113 A ZA200710113 A ZA 200710113A ZA 200710113 A ZA200710113 A ZA 200710113A ZA 200710113 B ZA200710113 B ZA 200710113B
Authority
ZA
South Africa
Prior art keywords
nanoparticulate clopidogrel
clopidogrel formulations
formulations
nanoparticulate
clopidogrel
Prior art date
Application number
ZA200710113A
Other languages
English (en)
Inventor
Gary G Liversidge
Jenkins Scott
Original Assignee
Elan Pharma Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Pharma Int Ltd filed Critical Elan Pharma Int Ltd
Publication of ZA200710113B publication Critical patent/ZA200710113B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200710113A 2005-05-10 2007-11-22 Nanoparticulate clopidogrel formulations ZA200710113B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67939805P 2005-05-10 2005-05-10

Publications (1)

Publication Number Publication Date
ZA200710113B true ZA200710113B (en) 2008-11-26

Family

ID=38180446

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200710113A ZA200710113B (en) 2005-05-10 2007-11-22 Nanoparticulate clopidogrel formulations

Country Status (14)

Country Link
US (1) US20070003628A1 (xx)
EP (1) EP1888037A2 (xx)
JP (1) JP2008540546A (xx)
KR (1) KR20080008403A (xx)
CN (1) CN101212954A (xx)
AU (1) AU2006336417A1 (xx)
BR (1) BRPI0608771A2 (xx)
CA (1) CA2607494A1 (xx)
EA (1) EA200702444A1 (xx)
IL (1) IL187258A0 (xx)
MX (1) MX2007014163A (xx)
NO (1) NO20076215L (xx)
WO (1) WO2007086914A2 (xx)
ZA (1) ZA200710113B (xx)

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CN101919890A (zh) * 2010-08-18 2010-12-22 徐震 一种含氯吡格雷硫酸氢盐的片剂及其制备方法
CN101912393B (zh) * 2010-08-25 2012-07-18 石药集团欧意药业有限公司 一种氯吡格雷或其可药用盐固体制剂及其制备方法
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KR101324862B1 (ko) * 2011-07-12 2013-11-01 (주)에이에스텍 클로피도그렐 황산수소염의 구형 입자, 이를 포함하는 약학적 조성물 및 이의 제조방법
CN102397253B (zh) * 2011-09-14 2013-01-23 海南灵康制药有限公司 硫酸氢氯吡格雷脂质体固体制剂
ES2791417T3 (es) 2013-02-06 2020-11-04 Jingjun Huang Composición farmacéutica estable de base libre de clopidogrel para administración oral y parenteral
CN113827562A (zh) * 2013-02-06 2021-12-24 黄敬珺 用于口服和胃肠外给药的稳定的氯吡格雷游离碱药物组合物
AU2014226290B2 (en) * 2013-03-04 2018-11-15 Vtv Therapeutics Llc Stable glucokinase activator compositions
CN104523627B (zh) * 2014-12-18 2017-04-12 成都苑东生物制药股份有限公司 一种硫酸氢氯吡格雷片药物组合物及其制备方法
CN110483088B (zh) * 2019-09-10 2021-10-29 四川广通碳复合材料有限公司 一种浸铜碳滑板及其制备方法
CN115518066A (zh) * 2022-06-17 2022-12-27 成都施贝康生物医药科技有限公司 一种用于治疗抗凝血的药物组合物及应用

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Also Published As

Publication number Publication date
CA2607494A1 (en) 2007-08-02
WO2007086914A2 (en) 2007-08-02
JP2008540546A (ja) 2008-11-20
US20070003628A1 (en) 2007-01-04
IL187258A0 (en) 2008-02-09
AU2006336417A1 (en) 2007-08-02
CN101212954A (zh) 2008-07-02
BRPI0608771A2 (pt) 2010-01-26
EP1888037A2 (en) 2008-02-20
NO20076215L (no) 2008-02-08
WO2007086914A3 (en) 2007-09-20
EA200702444A1 (ru) 2008-04-28
KR20080008403A (ko) 2008-01-23
MX2007014163A (es) 2008-01-24

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