ZA200709620B - Methods for treating drug resistant cancer - Google Patents

Methods for treating drug resistant cancer

Info

Publication number
ZA200709620B
ZA200709620B ZA200709620A ZA200709620A ZA200709620B ZA 200709620 B ZA200709620 B ZA 200709620B ZA 200709620 A ZA200709620 A ZA 200709620A ZA 200709620 A ZA200709620 A ZA 200709620A ZA 200709620 B ZA200709620 B ZA 200709620B
Authority
ZA
South Africa
Prior art keywords
methods
drug resistant
resistant cancer
treating drug
treating
Prior art date
Application number
ZA200709620A
Other languages
English (en)
Inventor
Glenn C Michelson
Vivien W Chan
Carla C Heise
Wiesmann Marion
Timothy D Dawes
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ZA200709620B publication Critical patent/ZA200709620B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
ZA200709620A 2005-05-13 2007-11-08 Methods for treating drug resistant cancer ZA200709620B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68072205P 2005-05-13 2005-05-13

Publications (1)

Publication Number Publication Date
ZA200709620B true ZA200709620B (en) 2008-10-29

Family

ID=37431829

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200709620A ZA200709620B (en) 2005-05-13 2007-11-08 Methods for treating drug resistant cancer

Country Status (23)

Country Link
US (1) US8299081B2 (zh)
EP (1) EP1885187B1 (zh)
JP (2) JP5344910B2 (zh)
KR (1) KR101319122B1 (zh)
CN (1) CN101222850B (zh)
AU (1) AU2006247803B2 (zh)
BR (1) BRPI0610360A2 (zh)
CA (1) CA2608171C (zh)
DK (1) DK1885187T3 (zh)
ES (1) ES2440799T3 (zh)
HK (1) HK1110477A1 (zh)
IL (1) IL187327A (zh)
MA (1) MA29543B1 (zh)
MX (1) MX2007014206A (zh)
NO (1) NO20076425L (zh)
NZ (1) NZ564144A (zh)
PL (1) PL1885187T3 (zh)
PT (1) PT1885187E (zh)
RU (1) RU2426539C2 (zh)
SI (1) SI1885187T1 (zh)
TN (1) TNSN07419A1 (zh)
WO (1) WO2006124413A2 (zh)
ZA (1) ZA200709620B (zh)

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CN101423513B (zh) * 2007-10-29 2013-03-27 中国医学科学院药物研究所 胺基嘧啶衍生物、及其制法和药物组合物与用途
PL2149372T3 (pl) * 2008-07-31 2015-03-31 Univ Ulm Zastosowanie opioidów z grupy metadonu w leczeniu opornych pacjentów onkologicznych
US9095592B2 (en) * 2008-11-07 2015-08-04 The Research Foundation For The State University Of New York Bruton's tyrosine kinase as anti-cancer drug target
US9519613B2 (en) * 2009-02-02 2016-12-13 Asurion, Llc Method for integrating applications in an electronic address book
TWI410418B (zh) 2009-04-29 2013-10-01 Ind Tech Res Inst 氮雜薁化合物、藥學組合物與抑制一細胞中蛋白質激酶之活性的方法
CA2795089A1 (en) * 2010-04-16 2011-10-20 Novartis Ag Combination of organic compounds
SG194445A1 (en) * 2011-05-19 2013-12-30 Novartis Ag Method for treating adenoid cystic carcinoma
WO2013063003A1 (en) 2011-10-28 2013-05-02 Novartis Ag Method of treating gastrointestinal stromal tumors
RU2014135436A (ru) * 2012-01-31 2016-03-27 Новартис Аг Комбинация ингибитора rtk с антиэстрогеном и ее применение для лечения рака
EP2872142A1 (en) * 2012-07-11 2015-05-20 Novartis AG Method of treating gastrointestinal stromal tumors
WO2014058785A1 (en) 2012-10-10 2014-04-17 Novartis Ag Combination therapy
RU2547999C1 (ru) * 2013-10-28 2015-04-10 Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) Способ лечения аденогенного местно-распространенного рака нижнеампулярного отдела прямой кишки
WO2016123054A2 (en) * 2015-01-26 2016-08-04 The University Of North Carolina At Chapel Hill Kinase drug combinations and methods of use thereof
US11136409B2 (en) * 2016-09-20 2021-10-05 Dana-Farber Cancer Institute, Inc. Compositions and methods for identification, assessment, prevention, and treatment of AML using USP10 biomarkers and modulators

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Also Published As

Publication number Publication date
MA29543B1 (fr) 2008-06-02
WO2006124413A3 (en) 2007-06-07
IL187327A (en) 2015-05-31
AU2006247803A1 (en) 2006-11-23
KR20080033902A (ko) 2008-04-17
NZ564144A (en) 2009-11-27
DK1885187T3 (da) 2013-12-09
EP1885187A2 (en) 2008-02-13
US8299081B2 (en) 2012-10-30
NO20076425L (no) 2008-01-30
CN101222850A (zh) 2008-07-16
US20090215793A1 (en) 2009-08-27
RU2426539C2 (ru) 2011-08-20
JP5344910B2 (ja) 2013-11-20
IL187327A0 (en) 2008-04-13
ES2440799T3 (es) 2014-01-30
EP1885187A4 (en) 2009-05-13
CN101222850B (zh) 2012-10-03
SI1885187T1 (sl) 2013-12-31
RU2007145932A (ru) 2009-06-20
CA2608171A1 (en) 2006-11-23
TNSN07419A1 (en) 2009-03-17
PL1885187T3 (pl) 2014-03-31
AU2006247803B2 (en) 2011-12-22
CA2608171C (en) 2014-02-04
PT1885187E (pt) 2013-12-16
HK1110477A1 (en) 2008-07-18
JP2008540543A (ja) 2008-11-20
EP1885187B1 (en) 2013-09-25
KR101319122B1 (ko) 2013-10-23
MX2007014206A (es) 2008-02-07
BRPI0610360A2 (pt) 2010-06-15
WO2006124413A2 (en) 2006-11-23
JP2013173787A (ja) 2013-09-05

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