ZA200705102B - Low-profile microneedle array applicator - Google Patents

Low-profile microneedle array applicator

Info

Publication number
ZA200705102B
ZA200705102B ZA200705102A ZA200705102A ZA200705102B ZA 200705102 B ZA200705102 B ZA 200705102B ZA 200705102 A ZA200705102 A ZA 200705102A ZA 200705102 A ZA200705102 A ZA 200705102A ZA 200705102 B ZA200705102 B ZA 200705102B
Authority
ZA
South Africa
Prior art keywords
low
microneedle array
array applicator
profile
profile microneedle
Prior art date
Application number
ZA200705102A
Other languages
English (en)
Inventor
Adam S Cantor
Peter R Johnson
Franklyn L Frederickson
Ted K Ringsred
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of ZA200705102B publication Critical patent/ZA200705102B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Micromachines (AREA)
ZA200705102A 2004-11-18 2007-06-15 Low-profile microneedle array applicator ZA200705102B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62921504P 2004-11-18 2004-11-18

Publications (1)

Publication Number Publication Date
ZA200705102B true ZA200705102B (en) 2008-10-29

Family

ID=35809616

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200705102A ZA200705102B (en) 2004-11-18 2007-06-15 Low-profile microneedle array applicator

Country Status (12)

Country Link
US (2) US8267889B2 (ja)
EP (1) EP1833547A1 (ja)
JP (2) JP2008520369A (ja)
KR (2) KR20130026511A (ja)
CN (1) CN101060883B (ja)
AU (1) AU2005306422A1 (ja)
BR (1) BRPI0517749A (ja)
CA (1) CA2587505C (ja)
IL (1) IL183204A (ja)
MX (1) MX2007005813A (ja)
WO (1) WO2006055795A1 (ja)
ZA (1) ZA200705102B (ja)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
AU2005228145B2 (en) * 2004-03-24 2011-03-03 Corium Pharma Solutions, Inc. Transdermal delivery device
CN101060883B (zh) 2004-11-18 2010-06-23 3M创新有限公司 低轮廓微针阵列施放器
JP5301985B2 (ja) 2005-04-07 2013-09-25 スリーエム イノベイティブ プロパティズ カンパニー ツールフィードバック感知のためのシステム及び方法
WO2007002523A2 (en) * 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
CA2620943A1 (en) * 2005-09-02 2007-03-08 Iomai Corporation Devices for transcutaneous delivery of vaccines and transdermal delivery of drugs and uses thereof
WO2007124411A1 (en) * 2006-04-20 2007-11-01 3M Innovative Properties Company Device for applying a microneedle array
KR100886633B1 (ko) * 2006-07-14 2009-03-04 호남석유화학 주식회사 전면부에 피부를 통해 체내로 전달하고자 하는 물질의 수용공간을 갖는 피부 침투용 미세 돌기 장치
EP1884223A1 (en) 2006-08-04 2008-02-06 IP Randwyck B.V. Wound-stimulating unit
EP2121111B1 (en) * 2007-01-22 2018-03-14 Corium International, Inc. Applicators for microneedle arrays
KR100893250B1 (ko) * 2007-02-28 2009-04-17 광주과학기술원 능동형 미세바늘 장치
JP4978245B2 (ja) * 2007-03-08 2012-07-18 凸版印刷株式会社 針状体、針状体製造方法および薬物輸送デバイス
GB2448493B (en) 2007-04-16 2009-10-14 Dewan Fazlul Hoque Chowdhury Microneedle transdermal delivery device
US9114238B2 (en) 2007-04-16 2015-08-25 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
JP5222512B2 (ja) * 2007-09-19 2013-06-26 凸版印刷株式会社 マイクロニードルチップ
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
JP5178132B2 (ja) * 2007-10-11 2013-04-10 キヤノン株式会社 画像処理システム並びに画像処理方法
KR101013581B1 (ko) 2008-08-06 2011-02-14 라종주 전기 피부 미용기
US20110150946A1 (en) * 2008-08-22 2011-06-23 Al-Ghananeem Abeer M Transdermal Delivery of Apomorphine Using Microneedles
EP2399643A4 (en) * 2009-02-23 2012-08-22 Medrx Co Ltd APPLICATOR FOR MICRO NEEDLE NETWORK
WO2010124255A2 (en) * 2009-04-24 2010-10-28 Corium International, Inc. Methods for manufacturing microprojection arrays
US20120184916A1 (en) * 2009-08-07 2012-07-19 Medrx Co., Ltd. Applicator device of pinholder type microneedle
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
US20110172638A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including multi-functional cover
US20110172645A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Wearable drug delivery device including integrated pumping and activation elements
US20110172639A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Device and method for delivery of microneedle to desired depth within the skin
US20110172609A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Microneedle component assembly for drug delivery device
US20110172637A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
CN103096970B (zh) 2010-01-22 2016-10-26 株式会社医药处方 用于微针粘附皮肤贴剂的粘附贴剂辅助工具
US8911422B2 (en) 2010-02-24 2014-12-16 Hisamitsu Pharmaceutical Co., Inc. Micro-needle device
ES2734560T3 (es) 2010-05-04 2019-12-10 Corium Int Inc Aplicadores para microagujas
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル, インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
WO2011141426A1 (en) 2010-05-10 2011-11-17 Tt Seed S.R.L. Needle device for detecting biosignals through the skin
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
CN101972499B (zh) * 2010-11-10 2016-07-06 吉林大学 轻松无痛输药装置
IT1403293B1 (it) 2010-12-27 2013-10-17 Fond Don Carlo Gnocchi Onlus Apparecchiatura ad aghi per la somministrazione transdermica di farmaci.
JP5908977B2 (ja) 2011-06-14 2016-04-26 ジョンジュ ナ ラ−効果またはラプラス−効果による皮膚改善装置及び方法
EP2764887B1 (en) 2011-10-06 2020-12-02 Hisamitsu Pharmaceutical Co., Inc. Applicator
CN103857423B (zh) * 2011-10-12 2016-09-07 3M创新有限公司 一体的微针阵列递送系统
US11179553B2 (en) 2011-10-12 2021-11-23 Vaxxas Pty Limited Delivery device
KR102022574B1 (ko) 2011-10-12 2019-09-18 쓰리엠 이노베이티브 프로퍼티즈 컴파니 통합된 마이크로니들 어레이 전달 시스템
US9011350B2 (en) 2011-11-30 2015-04-21 Lincoln Diagnostics, Inc. Allergy testing device and method of testing for allergies
US8469900B2 (en) 2011-11-30 2013-06-25 Lincoln Diagnostics, Inc. Allergy testing device and method of testing for allergies
DE102011089723A1 (de) 2011-12-23 2013-06-27 Robert Bosch Gmbh Mikronadelarray-Applikator und Verfahren zur Applikation eines Mikronadelarrays
US9944019B2 (en) 2012-05-01 2018-04-17 University of Pittsburgh—of the Commonwealth System of Higher Education Tip-loaded microneedle arrays for transdermal insertion
WO2013166484A1 (en) 2012-05-04 2013-11-07 Roger Khouri Surgical tools and methods for their use
JP5593355B2 (ja) * 2012-07-23 2014-09-24 凸版印刷株式会社 針状体および針状体製造方法
WO2014058746A1 (en) 2012-10-10 2014-04-17 3M Innovative Properties Company Force-controlled applicator for applying a microneedle device to skin
WO2014059104A1 (en) 2012-10-10 2014-04-17 3M Innovative Properties Company Applicator and method for applying a microneedle device to skin
EP2919849B1 (en) * 2012-11-16 2021-01-06 Kindeva Drug Delivery L.P. Force-controlled applicator for applying a microneedle device to skin
CN105142529A (zh) 2012-11-21 2015-12-09 电路治疗公司 用于光遗传疗法的系统和方法
AU2013364053B2 (en) 2012-12-21 2018-08-30 Corium Pharma Solutions, Inc. Microarray for delivery of therapeutic agent and methods of use
BR122020006959B1 (pt) 2013-03-12 2022-04-26 Corium, Inc Aplicador de microprojeções
EP2968119B1 (en) 2013-03-15 2019-09-18 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
JP2016514133A (ja) 2013-03-15 2016-05-19 コリウム インターナショナル, インコーポレイテッド ポリマーを含まない微細構造物を含むマイクロアレイ、製造方法および使用方法
BR112015022625B1 (pt) 2013-03-15 2023-01-31 Corium, Inc Aparelho de microestrutura para entrega de agente terapêutico
CA2903459C (en) 2013-03-15 2024-02-20 Corium International, Inc. Multiple impact microprojection applicators and methods of use
EP3027263A1 (en) 2013-07-30 2016-06-08 ZP Opco, Inc. Low-profile microneedle patch applicator
CN111744101B (zh) 2013-09-30 2023-03-10 佐治亚科技研究公司 微针贴片、系统和方法
JP6489025B2 (ja) * 2014-01-24 2019-03-27 凸版印刷株式会社 マイクロニードルユニット
WO2015111673A1 (ja) * 2014-01-24 2015-07-30 凸版印刷株式会社 マイクロニードルユニット、および、マイクロニードルアセンブリー
WO2015119906A1 (en) 2014-02-05 2015-08-13 Amgen Inc. Drug delivery system with electromagnetic field generator
USD763504S1 (en) 2014-04-02 2016-08-09 Hisamitsu Pharmaceutical Co., Inc. Cosmetic pack sheet
EP3134149A4 (en) 2014-04-24 2017-12-27 Georgia Tech Research Corporation Microneedles and methods of manufacture thereof
EP3188714A1 (en) 2014-09-04 2017-07-12 Corium International, Inc. Microstructure array, methods of making, and methods of use
JP6717207B2 (ja) * 2015-01-27 2020-07-01 凸版印刷株式会社 経皮投与デバイス
CA2975275C (en) 2015-02-02 2023-08-29 Vaxxas Pty Limited Microprojection array applicator and method
JPWO2016129184A1 (ja) * 2015-02-13 2017-04-27 株式会社 メドレックス マイクロニードルの穿刺装置及びマイクロニードルパッチの貼付装置
US10441768B2 (en) 2015-03-18 2019-10-15 University of Pittsburgh—of the Commonwealth System of Higher Education Bioactive components conjugated to substrates of microneedle arrays
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
CN108136165B (zh) 2015-09-02 2020-11-06 久光制药株式会社 施放器
US11103259B2 (en) 2015-09-18 2021-08-31 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
EP3355981A4 (en) 2015-09-28 2019-05-22 Vaxxas Pty Limited MICROPROJECTION ARRANGEMENTS WITH IMPROVED SKIN-IMPROPER PROPERTIES AND METHOD THEREFOR
KR101757866B1 (ko) * 2015-10-08 2017-07-14 주식회사 라파스 마이크로니들패치 포장케이스
US11684763B2 (en) 2015-10-16 2023-06-27 University of Pittsburgh—of the Commonwealth System of Higher Education Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices
EP3395397B1 (en) 2015-12-21 2022-10-12 Medrx Co., Ltd. Microneedle patch applicator housing
WO2017120322A1 (en) 2016-01-05 2017-07-13 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
US10500351B2 (en) * 2016-02-12 2019-12-10 Shawn Michael Michels Aid for subcutaneous tissue injection and process of effecting the injection with the aid
AU2017378040B2 (en) 2016-12-16 2023-06-08 Vivasor, Inc. Application device for a fluid delivery apparatus and method of use
KR101745445B1 (ko) * 2017-01-25 2017-06-09 송득영 가압형 약물 주입 시스템
EP4306803A3 (en) 2017-03-31 2024-04-10 Vaxxas Pty Limited Device and method for coating surfaces
JP2018191783A (ja) * 2017-05-15 2018-12-06 富士フイルム株式会社 マイクロニードルアレイユニット、および容器
JP2018192177A (ja) * 2017-05-22 2018-12-06 コスメディ製薬株式会社 水溶性化粧用シート保持フィルム
US11175128B2 (en) 2017-06-13 2021-11-16 Vaxxas Pty Limited Quality control of substrate coatings
EP4218893A1 (en) 2017-08-04 2023-08-02 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (map)
KR20190027233A (ko) * 2017-09-06 2019-03-14 주식회사 라파스 마이크로니들 보호 성능이 개선된 마이크로니들 패치 및 이러한 마이크로니들 패치와 어플리케이터로 구성되는 마이크로니들 패치 어플리케이터 시스템
US10786203B1 (en) * 2018-01-30 2020-09-29 Daniel M. Besser Medical patch applicator device
WO2019166572A1 (en) 2018-02-28 2019-09-06 Pharming Intellectual Property B.V. Pharmaceutical system for transdermal administration of a c1 -esterase inhibitor
EP3766537A4 (en) * 2018-03-13 2022-05-04 MEDRx Co., Ltd. ADHESIVE ELEMENT AND MICRONEEDLE PATCH
CN108671385A (zh) * 2018-06-21 2018-10-19 陈宏� 一种穴位自动贴敷直压微针及使用方法
JP1632957S (ja) 2018-10-30 2019-06-03
CN112996554B (zh) * 2018-10-31 2023-07-11 富士胶片株式会社 微针阵列器件
BR112021012467A2 (pt) * 2018-12-25 2021-09-08 Otsuka Pharmaceutical Factory, Inc. Dispositivo de administração de medicamento e sistema de administração de medicamento
JPWO2021251464A1 (ja) * 2020-06-12 2021-12-16
US11389632B2 (en) 2020-12-21 2022-07-19 Mediccene Inc. Intradermal drug delivery device
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US11452474B1 (en) 2021-04-14 2022-09-27 Satio, Inc. Dual lever dermal patch system
US11654270B2 (en) 2021-09-28 2023-05-23 Biolinq Incorporated Microneedle enclosure and applicator device for microneedle array based continuous analyte monitoring device
USD1033641S1 (en) 2021-12-17 2024-07-02 Biolinq Incorporated Microneedle array sensor applicator device
WO2024059152A2 (en) * 2022-09-13 2024-03-21 Micron Biomedical, Inc. Microneedle patch with force-feedback indicator

Family Cites Families (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123212A (en) 1964-03-03 Multiple disposable intracutaneous injector package
USRE25637E (en) 1964-09-08 Means for vaccinating
US3072122A (en) 1959-01-15 1963-01-08 Rosenthal Sol Roy Package for transcutaneous injection
US3034507A (en) 1960-05-10 1962-05-15 American Cyanamid Co Intracutaneous injection device
US3136314A (en) 1960-08-01 1964-06-09 Kravitz Harvey Vaccinating devices
US3246647A (en) 1962-07-23 1966-04-19 American Cyanamid Co Disposable intracutaneous injector
US3221740A (en) 1962-08-31 1965-12-07 Rosenthal Sol Roy Injection device
GB1080986A (en) 1964-09-02 1967-08-31 Allen And Hanburys Surgical En Multiple puncture apparatus
US3322121A (en) 1965-11-26 1967-05-30 Oscar H Banker Skin-puncturing unit with a collapsible protective cover
US3510933A (en) 1967-05-26 1970-05-12 American Cyanamid Co Apparatus and method for continuously forming intracutaneous injectors
US3466131A (en) 1967-09-07 1969-09-09 Becton Dickinson Co Dispensing applicator package
US3512520A (en) 1967-11-01 1970-05-19 Michael N Cowan Antigenic test applicator
US3596660A (en) 1969-05-12 1971-08-03 Illinois Tool Works Injection device
US3675766A (en) 1970-02-04 1972-07-11 Sol Roy Rosenthal Multiple puncture injector device
US3688764A (en) 1970-08-20 1972-09-05 Bard Hamilton Co Inc Intracutaneous injection system
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US3678150A (en) 1971-07-27 1972-07-18 American Cyanamid Co Process for improving the stability of ppd, qt and histoplasmin on tine applicators
DE2250293A1 (de) 1972-10-13 1974-04-25 Bayern Freistaat Impfstempel zur cutanen pockenimpfung mittels trockenimpfstoff
OA05448A (fr) 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
US4304241A (en) 1978-09-05 1981-12-08 Aller-Screen, Inc. Skin testing device
US4237906A (en) 1978-12-06 1980-12-09 Havstad Harold R Antigen injection assembly
GB2064329B (en) 1979-11-01 1983-06-22 Matburn Holdings Ltd Multiple puncture apparatus
FR2474856A1 (fr) 1980-01-31 1981-08-07 Merieux Inst Dispositif scarificateur
US4360016A (en) 1980-07-01 1982-11-23 Transidyne General Corp. Blood collecting device
US4503856A (en) 1981-06-29 1985-03-12 Sherwood Medical Company Lancet injector
US4517978A (en) 1983-01-13 1985-05-21 Levin Paul D Blood sampling instrument
US4474751A (en) 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
US4627445A (en) 1985-04-08 1986-12-09 Garid, Inc. Glucose medical monitoring system
GB8710470D0 (en) 1987-05-01 1987-06-03 Mumford Ltd Owen Blood sampling devices
US4858607A (en) 1987-10-16 1989-08-22 Pavel Jordan & Associates Plastic device for injection and obtaining blood samples
US5192535A (en) 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
GB2221394B (en) 1988-08-05 1992-03-04 Eilert Eilertsen An injection device
US4924879A (en) 1988-10-07 1990-05-15 Brien Walter J O Blood lancet device
US4920977A (en) 1988-10-25 1990-05-01 Becton, Dickinson And Company Blood collection assembly with lancet and microcollection tube
EP0429842B1 (en) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5402798A (en) 1991-07-18 1995-04-04 Swierczek; Remi Disposable skin perforator and blood testing device
DE4212315A1 (de) 1992-04-13 1993-10-14 Boehringer Mannheim Gmbh Blutlanzettenvorrichtung zur Entnahme von Blut für Diagnosezwecke
DE4212723C1 (de) * 1992-04-16 1993-11-04 Arta Plast Ab Tyresoe Lanzettenvorrichtung zum punktieren der haut
US5340572A (en) 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
JP2630197B2 (ja) 1993-04-28 1997-07-16 株式会社ニッショー 血液吸出器具
US5611806A (en) 1994-05-23 1997-03-18 Samsung Electro-Mechanics Co., Ltd. Skin perforating device for transdermal medication
US5487726A (en) 1994-06-16 1996-01-30 Ryder International Corporation Vaccine applicator system
US5636640A (en) * 1995-02-06 1997-06-10 Volunteers For Medical Engineering Liquid sampling and test apparatus
WO1996037256A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical patch for enhancing the delivery of compounds through the skin
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
ZA975326B (en) 1996-06-18 1998-01-14 Alza Corp Device and method for enhancing transdermal flux of agents being delivered or sampled.
CA2265906C (en) 1996-09-17 2003-11-11 Deka Products Limited Partnership System for delivery of drugs by transport
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US5968633A (en) * 1997-06-06 1999-10-19 The Procter & Gamble Company Selectively-activatible sheet material for dispensing and dispersing a substance onto a target surface
ATE406935T1 (de) 1997-12-11 2008-09-15 Alza Corp Vorrichtung zur verbesserung des transdermalen flusses von medikamenten
KR100572539B1 (ko) 1997-12-11 2006-04-24 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
CA2575064C (en) 1997-12-31 2010-02-02 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
US6091975A (en) 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
CA2229522A1 (en) * 1998-04-15 1999-10-15 Thomas Randall Inkpen Needle aid
EP1086214B1 (en) 1998-06-10 2009-11-25 Georgia Tech Research Corporation Microneedle devices and methods of their manufacture
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
GB9817662D0 (en) 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
WO2000012173A1 (en) 1998-08-31 2000-03-09 Johnson & Johnson Consumer Companies, Inc. Electrotransport device comprising blades
US6022368A (en) * 1998-11-30 2000-02-08 Gavronsky; Stas Acupuncture method and device
DE60007290T2 (de) 1999-01-28 2004-09-23 Cyto Pulse Sciences, Inc. Einbringen von makromolekülen in zellen
US6713291B2 (en) 1999-01-28 2004-03-30 Alan D. King Electrodes coated with treating agent and uses thereof
US6611707B1 (en) * 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
AU2005200910B2 (en) 1999-06-04 2006-08-03 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6312612B1 (en) 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6379324B1 (en) 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6623457B1 (en) 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US6835184B1 (en) 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
US20020095134A1 (en) 1999-10-14 2002-07-18 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
DK1239917T3 (da) 1999-12-10 2005-08-22 Alza Corp Hudbehandlingsapparat til vedvarende transdermal medikamentlevering
DE60024312T2 (de) 1999-12-10 2006-08-17 Alza Corp., Mountain View Transdermale Wirkstoffabgabe von makromolekularen Wirkstoffen und Vorrichtung hierfür
US6881538B1 (en) 2000-03-05 2005-04-19 3M Innovative Properties Company Array comprising diamond-like glass film
US6595947B1 (en) 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
AU2001275138A1 (en) 2000-06-02 2001-12-17 The University Of Utah Research Foundation Active needle devices with integrated functionality
US6537242B1 (en) 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US6589202B1 (en) 2000-06-29 2003-07-08 Becton Dickinson And Company Method and apparatus for transdermally sampling or administering a substance to a patient
US6440096B1 (en) 2000-07-14 2002-08-27 Becton, Dickinson And Co. Microdevice and method of manufacturing a microdevice
US6656147B1 (en) * 2000-07-17 2003-12-02 Becton, Dickinson And Company Method and delivery device for the transdermal administration of a substance
GB0017999D0 (en) 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
IL155375A0 (en) 2000-10-13 2003-11-23 Alza Corp Microblade array impact applicator
AU9682801A (en) 2000-10-13 2002-04-22 Alza Corp Apparatus and method for piercing skin with microprotrusions
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
HUP0303576A2 (en) 2000-10-13 2004-01-28 Alza Corp Microprotrusion member retainer for impact applicator
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
HUP0302924A2 (en) 2000-10-26 2003-12-29 Alza Corp Transdermal drug delivery devices having coated microprotrusions
WO2002045771A2 (en) 2000-11-09 2002-06-13 Biovalve Technologies, Inc. Microneedle adapter
ES2574917T3 (es) 2000-11-30 2016-06-23 Valeritas, Inc. Sistemas y procedimientos de suministro y medición de fluido
EP1345646A2 (en) 2000-12-14 2003-09-24 Georgia Tech Research Corporation Microneedle devices and production thereof
CN100349632C (zh) 2001-04-20 2007-11-21 阿尔扎公司 具有包含有益药剂的涂层的微小突出物阵列
US20020193729A1 (en) 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
US6591124B2 (en) 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
DE60213976T2 (de) * 2001-06-08 2007-04-26 Becton Dickinson And Co. Vorrichtung zur manipulation von nadeln oder polierarray
BR0210628A (pt) 2001-06-29 2004-08-10 Becton Dickinson Co Liberação intradérmica de vacinas e agentes terapêuticos genéticos via microcânula
US6881203B2 (en) 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
AU2002333554C1 (en) 2001-09-12 2008-12-11 Becton, Dickinson And Company Microneedle-based pen device for drug delivery and method for using same
US8920375B2 (en) 2001-09-21 2014-12-30 Valeritas, Inc. Gas pressure actuated microneedle arrays, and systems and methods relating to same
US6830562B2 (en) 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US6908453B2 (en) 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US7004928B2 (en) 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
US7858112B2 (en) 2002-02-28 2010-12-28 Lintec Corporation Percutaneous absorption system and percutaneous absorption method
JP4608187B2 (ja) * 2002-02-28 2011-01-05 リンテック株式会社 経皮吸収型製剤
US6780171B2 (en) 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
CA2490137C (en) * 2002-06-25 2012-01-03 Sung-Yun Kwon Rapidly dissolving micro-perforator for drug delivery and other applications
CN102872526A (zh) 2002-07-19 2013-01-16 3M创新有限公司 微针装置和微针施用设备
DK1523355T3 (en) 2002-07-22 2019-04-23 Becton Dickinson Co PLASTER-LIKE INFUSION DEVICE
ES2617576T3 (es) 2002-08-29 2017-06-19 Becton, Dickinson And Company Administración de sustancias mediante un sistema microabrasivo giratorio
WO2005000382A2 (en) 2003-06-04 2005-01-06 Georgia Tech Research Corporation Drilling microneedle device
UY28398A1 (es) 2003-07-02 2004-11-08 Alza Corp Método y parche de inmunización por disposición de microproyección
CA2535138C (en) 2003-08-12 2013-01-08 Becton, Dickinson And Company Patch-like infusion device
US8353861B2 (en) 2003-09-18 2013-01-15 Texmac, Inc. Applicator for applying functional substances into human skin
BRPI0415466A (pt) 2003-10-24 2006-12-19 Alza Corp método e sistema de pré-tratamento para intensificar a distribuição transdérmica de fármacos
CN1897882A (zh) 2003-10-28 2007-01-17 阿尔扎公司 降低烟草使用频率的方法和装置
JP4682144B2 (ja) 2003-10-31 2011-05-11 アルザ・コーポレーシヨン 微小突起列のための自己−作動性アプリケーター
US20050228313A1 (en) 2003-12-04 2005-10-13 University Technologies International Inc. Fluid sampling, analysis and delivery system
EP1696983A2 (en) 2003-12-18 2006-09-06 Novo Nordisk A/S Nozzle device with skin stretching means
US20070073220A1 (en) 2004-10-06 2007-03-29 Philip Bunce Inoculation device
CN101060883B (zh) 2004-11-18 2010-06-23 3M创新有限公司 低轮廓微针阵列施放器
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
CA2589733C (en) 2004-12-07 2014-02-11 3M Innovative Properties Company Method of molding a microneedle
WO2007002523A2 (en) 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
EP2474338B1 (en) 2005-06-27 2013-07-24 3M Innovative Properties Company Microneedle array applicator device
US7658728B2 (en) 2006-01-10 2010-02-09 Yuzhakov Vadim V Microneedle array, patch, and applicator for transdermal drug delivery
WO2007124411A1 (en) 2006-04-20 2007-11-01 3M Innovative Properties Company Device for applying a microneedle array
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism

Also Published As

Publication number Publication date
IL183204A (en) 2013-07-31
IL183204A0 (en) 2007-08-19
WO2006055795A1 (en) 2006-05-26
CA2587505C (en) 2013-01-08
US20080114298A1 (en) 2008-05-15
JP2008520369A (ja) 2008-06-19
EP1833547A1 (en) 2007-09-19
JP5587946B2 (ja) 2014-09-10
CA2587505A1 (en) 2006-05-26
CN101060883A (zh) 2007-10-24
US20130006219A1 (en) 2013-01-03
AU2005306422A1 (en) 2006-05-26
KR20070102669A (ko) 2007-10-19
KR20130026511A (ko) 2013-03-13
US8267889B2 (en) 2012-09-18
JP2012183358A (ja) 2012-09-27
US8758298B2 (en) 2014-06-24
CN101060883B (zh) 2010-06-23
MX2007005813A (es) 2007-07-18
BRPI0517749A (pt) 2008-10-21

Similar Documents

Publication Publication Date Title
IL183204A0 (en) Low-profile microneedle array applicator
GB0614595D0 (en) Multi Directional Applicator
GB0524064D0 (en) Applicator
GB0415973D0 (en) Radiation applicator
GB2414863B (en) Array antenna
EP1938809A4 (en) ADHESIVE SKIN PATCH
LT1898810T (lt) Aplikatorius
EP1935278A4 (en) BUILT-IN COSMETIC APPLICATOR
GB0402861D0 (en) Adhesive applicator
HK1098371A1 (en) Cosmetic
EP1949814A4 (en) APPLICATOR FOR COSMETIC PRODUCTS
GB2410682B (en) Extending applicator brush
GB2414664B (en) A substance applicator
AU155996S (en) Applicator
EP1666272A4 (en) APPLICATOR
AU2015200337B2 (en) Microneedle array applicator device
AU158431S (en) Applicator
GB0512304D0 (en) Lipstick applicator
GB2425718B (en) Improved cosmetics applicator
AU301298S (en) Applicator
GB0403426D0 (en) Yeeben applicator
GB0421761D0 (en) Cosmetic applicator
GB0424418D0 (en) Pansaver array
EP1819220A4 (en) ADMINISTRATIVE DEVICE IN GARDENING
AU2004905914A0 (en) Flexible magnetised portion applicator