ZA200705015B - Fluoridation process for the synthesis of 2-[18F] fluoro-2-deoxy-D-glucose - Google Patents
Fluoridation process for the synthesis of 2-[18F] fluoro-2-deoxy-D-glucoseInfo
- Publication number
- ZA200705015B ZA200705015B ZA200705015A ZA200705015A ZA200705015B ZA 200705015 B ZA200705015 B ZA 200705015B ZA 200705015 A ZA200705015 A ZA 200705015A ZA 200705015 A ZA200705015 A ZA 200705015A ZA 200705015 B ZA200705015 B ZA 200705015B
- Authority
- ZA
- South Africa
- Prior art keywords
- deoxy
- fluoro
- glucose
- synthesis
- fluoridation process
- Prior art date
Links
- 238000004334 fluoridation Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- AOYNUTHNTBLRMT-MXWOLSILSA-N 2-Deoxy-2(F-18)fluoro-2-D-glucose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H]([18F])C=O AOYNUTHNTBLRMT-MXWOLSILSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/02—Monosaccharides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0425501.4A GB0425501D0 (en) | 2004-11-19 | 2004-11-19 | Fluoridation process |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200705015B true ZA200705015B (en) | 2008-09-25 |
Family
ID=33548541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200705015A ZA200705015B (en) | 2004-11-19 | 2007-06-04 | Fluoridation process for the synthesis of 2-[18F] fluoro-2-deoxy-D-glucose |
Country Status (22)
Country | Link |
---|---|
US (1) | US20090076259A1 (es) |
EP (1) | EP1817320B1 (es) |
JP (1) | JP5318416B2 (es) |
KR (1) | KR101267122B1 (es) |
CN (1) | CN101061130B (es) |
AT (1) | ATE472552T1 (es) |
AU (1) | AU2005305624B2 (es) |
BR (1) | BRPI0518316A2 (es) |
CA (1) | CA2584649C (es) |
DE (1) | DE602005022099D1 (es) |
ES (1) | ES2347165T3 (es) |
GB (1) | GB0425501D0 (es) |
HK (1) | HK1107353A1 (es) |
IL (1) | IL182740A0 (es) |
MX (1) | MX2007006052A (es) |
NO (1) | NO20073037L (es) |
NZ (1) | NZ554613A (es) |
PL (1) | PL1817320T3 (es) |
PT (1) | PT1817320E (es) |
RU (1) | RU2394040C2 (es) |
WO (1) | WO2006054098A2 (es) |
ZA (1) | ZA200705015B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007031647A (ja) * | 2005-07-29 | 2007-02-08 | Japan Health Science Foundation | 固相合成を利用した超短半減期核種を含む化合物の製造方法およびそれに用いる化合物 |
CA2632133A1 (en) * | 2005-12-06 | 2007-06-14 | Nihon Medi-Physics Co., Ltd. | Process for production of compound labeled with radioactive fluorine |
KR20090063242A (ko) * | 2006-09-06 | 2009-06-17 | 니혼 메디피직스 가부시키가이샤 | 방사성 불소표지 유기화합물의 제조방법, 합성 장치 및 프로그램 |
KR20090093992A (ko) * | 2006-12-21 | 2009-09-02 | 해머스미쓰 이마네트 리미티드 | 미세 제조 장치를 사용하는 친핵 방사성 불화 |
CN102753561B (zh) | 2010-02-12 | 2015-10-21 | 国立大学法人东京工业大学 | 18f标记化合物的制造方法和该方法中使用的高分子化合物 |
US9023316B2 (en) | 2010-04-08 | 2015-05-05 | Siemens Medical Solutions Usa, Inc. | Synthesis of 18F-labeled tracers in hydrous organic solvents |
WO2012089594A1 (en) | 2010-12-29 | 2012-07-05 | Ge Healthcare Limited | Eluent solution |
US9101895B2 (en) | 2011-04-15 | 2015-08-11 | General Electric Company | System for mixing and dispersing microbubble pharmaceuticals |
US20140256970A1 (en) * | 2011-09-30 | 2014-09-11 | Ge Healthcare Limited | Reactor for multi-step radiochemistry |
JP6758065B2 (ja) * | 2016-03-30 | 2020-09-23 | 日本メジフィジックス株式会社 | 放射性標識化合物の製造装置及び製造方法 |
CN113801173B (zh) * | 2021-09-24 | 2024-03-12 | 上海安迪科正电子技术有限公司 | 一种氟-18标记的脱氧葡糖注射液的制备方法及应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2581558B1 (fr) * | 1985-05-10 | 1987-06-26 | Elf France | Procede de traitement d'un carburant compose d'un melange d'hydrocarbures et d'alcools, et produit d'adsorption selective d'eau |
GB0115927D0 (en) * | 2001-06-29 | 2001-08-22 | Nycomed Amersham Plc | Solid-phase nucleophilic fluorination |
-
2004
- 2004-11-19 GB GBGB0425501.4A patent/GB0425501D0/en not_active Ceased
-
2005
- 2005-11-18 RU RU2007115903/04A patent/RU2394040C2/ru active IP Right Revival
- 2005-11-18 BR BRPI0518316-2A patent/BRPI0518316A2/pt not_active Application Discontinuation
- 2005-11-18 PL PL05813632T patent/PL1817320T3/pl unknown
- 2005-11-18 WO PCT/GB2005/004451 patent/WO2006054098A2/en active Application Filing
- 2005-11-18 PT PT05813632T patent/PT1817320E/pt unknown
- 2005-11-18 JP JP2007542100A patent/JP5318416B2/ja active Active
- 2005-11-18 KR KR1020077011340A patent/KR101267122B1/ko active IP Right Grant
- 2005-11-18 CN CN2005800394892A patent/CN101061130B/zh not_active Expired - Fee Related
- 2005-11-18 EP EP05813632A patent/EP1817320B1/en not_active Not-in-force
- 2005-11-18 ES ES05813632T patent/ES2347165T3/es active Active
- 2005-11-18 NZ NZ554613A patent/NZ554613A/en not_active IP Right Cessation
- 2005-11-18 US US11/719,601 patent/US20090076259A1/en not_active Abandoned
- 2005-11-18 MX MX2007006052A patent/MX2007006052A/es active IP Right Grant
- 2005-11-18 AU AU2005305624A patent/AU2005305624B2/en not_active Ceased
- 2005-11-18 DE DE602005022099T patent/DE602005022099D1/de active Active
- 2005-11-18 AT AT05813632T patent/ATE472552T1/de not_active IP Right Cessation
- 2005-11-18 CA CA2584649A patent/CA2584649C/en not_active Expired - Fee Related
-
2007
- 2007-04-23 IL IL182740A patent/IL182740A0/en not_active IP Right Cessation
- 2007-06-04 ZA ZA200705015A patent/ZA200705015B/xx unknown
- 2007-06-14 NO NO20073037A patent/NO20073037L/no not_active Application Discontinuation
-
2008
- 2008-01-28 HK HK08101069.6A patent/HK1107353A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PT1817320E (pt) | 2010-09-13 |
AU2005305624A1 (en) | 2006-05-26 |
GB0425501D0 (en) | 2004-12-22 |
CN101061130A (zh) | 2007-10-24 |
RU2007115903A (ru) | 2008-12-27 |
BRPI0518316A2 (pt) | 2008-11-11 |
WO2006054098A2 (en) | 2006-05-26 |
CA2584649C (en) | 2013-09-24 |
CA2584649A1 (en) | 2006-05-26 |
KR101267122B1 (ko) | 2013-05-24 |
HK1107353A1 (en) | 2008-04-03 |
NZ554613A (en) | 2011-01-28 |
CN101061130B (zh) | 2012-08-15 |
AU2005305624B2 (en) | 2012-05-10 |
IL182740A0 (en) | 2007-07-24 |
ATE472552T1 (de) | 2010-07-15 |
MX2007006052A (es) | 2007-07-10 |
ES2347165T3 (es) | 2010-10-26 |
JP2008520636A (ja) | 2008-06-19 |
KR20070084361A (ko) | 2007-08-24 |
NO20073037L (no) | 2007-08-16 |
WO2006054098A3 (en) | 2006-08-03 |
DE602005022099D1 (de) | 2010-08-12 |
EP1817320A2 (en) | 2007-08-15 |
PL1817320T3 (pl) | 2010-11-30 |
RU2394040C2 (ru) | 2010-07-10 |
US20090076259A1 (en) | 2009-03-19 |
JP5318416B2 (ja) | 2013-10-16 |
EP1817320B1 (en) | 2010-06-30 |
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