PL1817320T3 - Sposób fluorkowania do syntezy 2-[18F]fluoro-2-dezoksy-D-glukozy - Google Patents
Sposób fluorkowania do syntezy 2-[18F]fluoro-2-dezoksy-D-glukozyInfo
- Publication number
- PL1817320T3 PL1817320T3 PL05813632T PL05813632T PL1817320T3 PL 1817320 T3 PL1817320 T3 PL 1817320T3 PL 05813632 T PL05813632 T PL 05813632T PL 05813632 T PL05813632 T PL 05813632T PL 1817320 T3 PL1817320 T3 PL 1817320T3
- Authority
- PL
- Poland
- Prior art keywords
- deoxy
- fluoro
- glucose
- synthesis
- fluoridation process
- Prior art date
Links
- 238000004334 fluoridation Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- AOYNUTHNTBLRMT-MXWOLSILSA-N 2-Deoxy-2(F-18)fluoro-2-D-glucose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H]([18F])C=O AOYNUTHNTBLRMT-MXWOLSILSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/02—Monosaccharides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Optics & Photonics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0425501.4A GB0425501D0 (en) | 2004-11-19 | 2004-11-19 | Fluoridation process |
PCT/GB2005/004451 WO2006054098A2 (en) | 2004-11-19 | 2005-11-18 | Fluoridation process for the synthesis of 2- [18f] fluoro-2-deoxy-d-glucose |
EP05813632A EP1817320B1 (en) | 2004-11-19 | 2005-11-18 | Fluoridation process for the synthesis of 2-[18f] fluoro-2-deoxy-d-glucose |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1817320T3 true PL1817320T3 (pl) | 2010-11-30 |
Family
ID=33548541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL05813632T PL1817320T3 (pl) | 2004-11-19 | 2005-11-18 | Sposób fluorkowania do syntezy 2-[18F]fluoro-2-dezoksy-D-glukozy |
Country Status (22)
Country | Link |
---|---|
US (1) | US20090076259A1 (pl) |
EP (1) | EP1817320B1 (pl) |
JP (1) | JP5318416B2 (pl) |
KR (1) | KR101267122B1 (pl) |
CN (1) | CN101061130B (pl) |
AT (1) | ATE472552T1 (pl) |
AU (1) | AU2005305624B2 (pl) |
BR (1) | BRPI0518316A2 (pl) |
CA (1) | CA2584649C (pl) |
DE (1) | DE602005022099D1 (pl) |
ES (1) | ES2347165T3 (pl) |
GB (1) | GB0425501D0 (pl) |
HK (1) | HK1107353A1 (pl) |
IL (1) | IL182740A0 (pl) |
MX (1) | MX2007006052A (pl) |
NO (1) | NO20073037L (pl) |
NZ (1) | NZ554613A (pl) |
PL (1) | PL1817320T3 (pl) |
PT (1) | PT1817320E (pl) |
RU (1) | RU2394040C2 (pl) |
WO (1) | WO2006054098A2 (pl) |
ZA (1) | ZA200705015B (pl) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007031647A (ja) * | 2005-07-29 | 2007-02-08 | Japan Health Science Foundation | 固相合成を利用した超短半減期核種を含む化合物の製造方法およびそれに用いる化合物 |
CN101346392A (zh) * | 2005-12-06 | 2009-01-14 | 日本医事物理股份有限公司 | 放射性氟标记化合物的制备方法 |
JP4287502B2 (ja) * | 2006-09-06 | 2009-07-01 | 日本メジフィジックス株式会社 | 放射性フッ素標識有機化合物の製造方法、合成装置およびプログラム |
WO2008140616A2 (en) * | 2006-12-21 | 2008-11-20 | Hammersmith Imanet Limited | Nucleophilic radiofluorination using microfabricated devices |
US9073802B2 (en) | 2010-02-12 | 2015-07-07 | Tokyo Institute Of Technology | Method for producing 18F-labeled compound and high molecular compound to be used in the method |
WO2011127345A1 (en) * | 2010-04-08 | 2011-10-13 | Siemens Medical Solutions Usa, Inc. | Synthesis of 18f-labeled tracers in hydrous organic solvents |
US11504430B2 (en) | 2010-12-29 | 2022-11-22 | Ge Healthcare Limited | Eluent solution |
US9101895B2 (en) | 2011-04-15 | 2015-08-11 | General Electric Company | System for mixing and dispersing microbubble pharmaceuticals |
EP2760577A2 (en) * | 2011-09-30 | 2014-08-06 | GE Healthcare UK Limited | Reactor for multi-step radiochemistry |
JP6758065B2 (ja) * | 2016-03-30 | 2020-09-23 | 日本メジフィジックス株式会社 | 放射性標識化合物の製造装置及び製造方法 |
CN113801173B (zh) * | 2021-09-24 | 2024-03-12 | 上海安迪科正电子技术有限公司 | 一种氟-18标记的脱氧葡糖注射液的制备方法及应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2581558B1 (fr) * | 1985-05-10 | 1987-06-26 | Elf France | Procede de traitement d'un carburant compose d'un melange d'hydrocarbures et d'alcools, et produit d'adsorption selective d'eau |
GB0115927D0 (en) * | 2001-06-29 | 2001-08-22 | Nycomed Amersham Plc | Solid-phase nucleophilic fluorination |
-
2004
- 2004-11-19 GB GBGB0425501.4A patent/GB0425501D0/en not_active Ceased
-
2005
- 2005-11-18 KR KR1020077011340A patent/KR101267122B1/ko active IP Right Grant
- 2005-11-18 PT PT05813632T patent/PT1817320E/pt unknown
- 2005-11-18 AT AT05813632T patent/ATE472552T1/de not_active IP Right Cessation
- 2005-11-18 AU AU2005305624A patent/AU2005305624B2/en not_active Ceased
- 2005-11-18 CA CA2584649A patent/CA2584649C/en not_active Expired - Fee Related
- 2005-11-18 CN CN2005800394892A patent/CN101061130B/zh not_active Expired - Fee Related
- 2005-11-18 BR BRPI0518316-2A patent/BRPI0518316A2/pt not_active Application Discontinuation
- 2005-11-18 MX MX2007006052A patent/MX2007006052A/es active IP Right Grant
- 2005-11-18 WO PCT/GB2005/004451 patent/WO2006054098A2/en active Application Filing
- 2005-11-18 ES ES05813632T patent/ES2347165T3/es active Active
- 2005-11-18 NZ NZ554613A patent/NZ554613A/en not_active IP Right Cessation
- 2005-11-18 PL PL05813632T patent/PL1817320T3/pl unknown
- 2005-11-18 DE DE602005022099T patent/DE602005022099D1/de active Active
- 2005-11-18 JP JP2007542100A patent/JP5318416B2/ja active Active
- 2005-11-18 EP EP05813632A patent/EP1817320B1/en not_active Not-in-force
- 2005-11-18 US US11/719,601 patent/US20090076259A1/en not_active Abandoned
- 2005-11-18 RU RU2007115903/04A patent/RU2394040C2/ru active IP Right Revival
-
2007
- 2007-04-23 IL IL182740A patent/IL182740A0/en not_active IP Right Cessation
- 2007-06-04 ZA ZA200705015A patent/ZA200705015B/xx unknown
- 2007-06-14 NO NO20073037A patent/NO20073037L/no not_active Application Discontinuation
-
2008
- 2008-01-28 HK HK08101069.6A patent/HK1107353A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE602005022099D1 (de) | 2010-08-12 |
JP2008520636A (ja) | 2008-06-19 |
GB0425501D0 (en) | 2004-12-22 |
EP1817320B1 (en) | 2010-06-30 |
HK1107353A1 (en) | 2008-04-03 |
ES2347165T3 (es) | 2010-10-26 |
WO2006054098A2 (en) | 2006-05-26 |
CN101061130A (zh) | 2007-10-24 |
NZ554613A (en) | 2011-01-28 |
WO2006054098A3 (en) | 2006-08-03 |
CA2584649C (en) | 2013-09-24 |
ZA200705015B (en) | 2008-09-25 |
CA2584649A1 (en) | 2006-05-26 |
IL182740A0 (en) | 2007-07-24 |
NO20073037L (no) | 2007-08-16 |
BRPI0518316A2 (pt) | 2008-11-11 |
AU2005305624B2 (en) | 2012-05-10 |
AU2005305624A1 (en) | 2006-05-26 |
US20090076259A1 (en) | 2009-03-19 |
JP5318416B2 (ja) | 2013-10-16 |
CN101061130B (zh) | 2012-08-15 |
RU2394040C2 (ru) | 2010-07-10 |
EP1817320A2 (en) | 2007-08-15 |
ATE472552T1 (de) | 2010-07-15 |
PT1817320E (pt) | 2010-09-13 |
KR20070084361A (ko) | 2007-08-24 |
MX2007006052A (es) | 2007-07-10 |
RU2007115903A (ru) | 2008-12-27 |
KR101267122B1 (ko) | 2013-05-24 |
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