PL1817320T3 - Sposób fluorkowania do syntezy 2-[18F]fluoro-2-dezoksy-D-glukozy - Google Patents

Sposób fluorkowania do syntezy 2-[18F]fluoro-2-dezoksy-D-glukozy

Info

Publication number
PL1817320T3
PL1817320T3 PL05813632T PL05813632T PL1817320T3 PL 1817320 T3 PL1817320 T3 PL 1817320T3 PL 05813632 T PL05813632 T PL 05813632T PL 05813632 T PL05813632 T PL 05813632T PL 1817320 T3 PL1817320 T3 PL 1817320T3
Authority
PL
Poland
Prior art keywords
deoxy
fluoro
glucose
synthesis
fluoridation process
Prior art date
Application number
PL05813632T
Other languages
English (en)
Inventor
Nigel John Osborn
Julian Grigg
Roger Paul Pettitt
Anthony Wilson
Nigel Anthony Powell
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of PL1817320T3 publication Critical patent/PL1817320T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0491Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/10Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02Monosaccharides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
PL05813632T 2004-11-19 2005-11-18 Sposób fluorkowania do syntezy 2-[18F]fluoro-2-dezoksy-D-glukozy PL1817320T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0425501.4A GB0425501D0 (en) 2004-11-19 2004-11-19 Fluoridation process
EP05813632A EP1817320B1 (en) 2004-11-19 2005-11-18 Fluoridation process for the synthesis of 2-[18f] fluoro-2-deoxy-d-glucose
PCT/GB2005/004451 WO2006054098A2 (en) 2004-11-19 2005-11-18 Fluoridation process for the synthesis of 2- [18f] fluoro-2-deoxy-d-glucose

Publications (1)

Publication Number Publication Date
PL1817320T3 true PL1817320T3 (pl) 2010-11-30

Family

ID=33548541

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05813632T PL1817320T3 (pl) 2004-11-19 2005-11-18 Sposób fluorkowania do syntezy 2-[18F]fluoro-2-dezoksy-D-glukozy

Country Status (22)

Country Link
US (1) US20090076259A1 (pl)
EP (1) EP1817320B1 (pl)
JP (1) JP5318416B2 (pl)
KR (1) KR101267122B1 (pl)
CN (1) CN101061130B (pl)
AT (1) ATE472552T1 (pl)
AU (1) AU2005305624B2 (pl)
BR (1) BRPI0518316A2 (pl)
CA (1) CA2584649C (pl)
DE (1) DE602005022099D1 (pl)
ES (1) ES2347165T3 (pl)
GB (1) GB0425501D0 (pl)
HK (1) HK1107353A1 (pl)
IL (1) IL182740A0 (pl)
MX (1) MX2007006052A (pl)
NO (1) NO20073037L (pl)
NZ (1) NZ554613A (pl)
PL (1) PL1817320T3 (pl)
PT (1) PT1817320E (pl)
RU (1) RU2394040C2 (pl)
WO (1) WO2006054098A2 (pl)
ZA (1) ZA200705015B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007031647A (ja) * 2005-07-29 2007-02-08 Japan Health Science Foundation 固相合成を利用した超短半減期核種を含む化合物の製造方法およびそれに用いる化合物
KR20080074145A (ko) * 2005-12-06 2008-08-12 니혼 메디피직스 가부시키가이샤 방사성 불소 표식 유기 화합물의 제조 방법
JP4287502B2 (ja) * 2006-09-06 2009-07-01 日本メジフィジックス株式会社 放射性フッ素標識有機化合物の製造方法、合成装置およびプログラム
WO2008140616A2 (en) * 2006-12-21 2008-11-20 Hammersmith Imanet Limited Nucleophilic radiofluorination using microfabricated devices
US9073802B2 (en) 2010-02-12 2015-07-07 Tokyo Institute Of Technology Method for producing 18F-labeled compound and high molecular compound to be used in the method
KR101430422B1 (ko) 2010-04-08 2014-08-14 지멘스 메디컬 솔루션즈 유에스에이, 인크. 함수 유기 용매에서 18f-표지된 트레이서의 합성
KR20130132892A (ko) * 2010-12-29 2013-12-05 지이 헬쓰케어 리미티드 용리제 용액
US9101895B2 (en) 2011-04-15 2015-08-11 General Electric Company System for mixing and dispersing microbubble pharmaceuticals
AU2012315883A1 (en) * 2011-09-30 2014-04-17 Ge Healthcare Limited Reactor for multi-step radiochemistry
JP6758065B2 (ja) * 2016-03-30 2020-09-23 日本メジフィジックス株式会社 放射性標識化合物の製造装置及び製造方法
CN113801173B (zh) * 2021-09-24 2024-03-12 上海安迪科正电子技术有限公司 一种氟-18标记的脱氧葡糖注射液的制备方法及应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2581558B1 (fr) * 1985-05-10 1987-06-26 Elf France Procede de traitement d'un carburant compose d'un melange d'hydrocarbures et d'alcools, et produit d'adsorption selective d'eau
GB0115927D0 (en) * 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase nucleophilic fluorination

Also Published As

Publication number Publication date
ZA200705015B (en) 2008-09-25
KR20070084361A (ko) 2007-08-24
AU2005305624B2 (en) 2012-05-10
AU2005305624A1 (en) 2006-05-26
DE602005022099D1 (de) 2010-08-12
WO2006054098A3 (en) 2006-08-03
GB0425501D0 (en) 2004-12-22
NZ554613A (en) 2011-01-28
JP2008520636A (ja) 2008-06-19
IL182740A0 (en) 2007-07-24
ATE472552T1 (de) 2010-07-15
US20090076259A1 (en) 2009-03-19
NO20073037L (no) 2007-08-16
CN101061130A (zh) 2007-10-24
MX2007006052A (es) 2007-07-10
EP1817320B1 (en) 2010-06-30
CN101061130B (zh) 2012-08-15
JP5318416B2 (ja) 2013-10-16
CA2584649A1 (en) 2006-05-26
BRPI0518316A2 (pt) 2008-11-11
EP1817320A2 (en) 2007-08-15
CA2584649C (en) 2013-09-24
ES2347165T3 (es) 2010-10-26
WO2006054098A2 (en) 2006-05-26
RU2394040C2 (ru) 2010-07-10
PT1817320E (pt) 2010-09-13
RU2007115903A (ru) 2008-12-27
KR101267122B1 (ko) 2013-05-24
HK1107353A1 (en) 2008-04-03

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