MX2007006052A - Procedimiento de fluorizacion para la sintesis de 2-[18f]fluoro-2-desoxi-d-glucosa. - Google Patents

Procedimiento de fluorizacion para la sintesis de 2-[18f]fluoro-2-desoxi-d-glucosa.

Info

Publication number
MX2007006052A
MX2007006052A MX2007006052A MX2007006052A MX2007006052A MX 2007006052 A MX2007006052 A MX 2007006052A MX 2007006052 A MX2007006052 A MX 2007006052A MX 2007006052 A MX2007006052 A MX 2007006052A MX 2007006052 A MX2007006052 A MX 2007006052A
Authority
MX
Mexico
Prior art keywords
deoxy
fluoro
glucose
synthesis
fluoridation process
Prior art date
Application number
MX2007006052A
Other languages
English (en)
Inventor
Nigel Anthony Powell
Nigel John Osborn
Julian Grigg
Roger Paul Pettitt
Anthony Wilson
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of MX2007006052A publication Critical patent/MX2007006052A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02—Monosaccharides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La invencion se refiere a un procedimiento mejorado para la fluorizacion de derivados de azucar en donde una cantidad controlada de agua esta presente en el solvente.
MX2007006052A 2004-11-19 2005-11-18 Procedimiento de fluorizacion para la sintesis de 2-[18f]fluoro-2-desoxi-d-glucosa. MX2007006052A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0425501.4A GB0425501D0 (en) 2004-11-19 2004-11-19 Fluoridation process
PCT/GB2005/004451 WO2006054098A2 (en) 2004-11-19 2005-11-18 Fluoridation process for the synthesis of 2- [18f] fluoro-2-deoxy-d-glucose

Publications (1)

Publication Number Publication Date
MX2007006052A true MX2007006052A (es) 2007-07-10

Family

ID=33548541

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007006052A MX2007006052A (es) 2004-11-19 2005-11-18 Procedimiento de fluorizacion para la sintesis de 2-[18f]fluoro-2-desoxi-d-glucosa.

Country Status (22)

Country Link
US (1) US20090076259A1 (es)
EP (1) EP1817320B1 (es)
JP (1) JP5318416B2 (es)
KR (1) KR101267122B1 (es)
CN (1) CN101061130B (es)
AT (1) ATE472552T1 (es)
AU (1) AU2005305624B2 (es)
BR (1) BRPI0518316A2 (es)
CA (1) CA2584649C (es)
DE (1) DE602005022099D1 (es)
ES (1) ES2347165T3 (es)
GB (1) GB0425501D0 (es)
HK (1) HK1107353A1 (es)
IL (1) IL182740A0 (es)
MX (1) MX2007006052A (es)
NO (1) NO20073037L (es)
NZ (1) NZ554613A (es)
PL (1) PL1817320T3 (es)
PT (1) PT1817320E (es)
RU (1) RU2394040C2 (es)
WO (1) WO2006054098A2 (es)
ZA (1) ZA200705015B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007031647A (ja) * 2005-07-29 2007-02-08 Japan Health Science Foundation 固相合成を利用した超短半減期核種を含む化合物の製造方法およびそれに用いる化合物
CA2632133A1 (en) * 2005-12-06 2007-06-14 Nihon Medi-Physics Co., Ltd. Process for production of compound labeled with radioactive fluorine
KR20090063242A (ko) * 2006-09-06 2009-06-17 니혼 메디피직스 가부시키가이샤 방사성 불소표지 유기화합물의 제조방법, 합성 장치 및 프로그램
KR20090093992A (ko) * 2006-12-21 2009-09-02 해머스미쓰 이마네트 리미티드 미세 제조 장치를 사용하는 친핵 방사성 불화
CN102753561B (zh) 2010-02-12 2015-10-21 国立大学法人东京工业大学 18f标记化合物的制造方法和该方法中使用的高分子化合物
US9023316B2 (en) 2010-04-08 2015-05-05 Siemens Medical Solutions Usa, Inc. Synthesis of 18F-labeled tracers in hydrous organic solvents
WO2012089594A1 (en) 2010-12-29 2012-07-05 Ge Healthcare Limited Eluent solution
US9101895B2 (en) 2011-04-15 2015-08-11 General Electric Company System for mixing and dispersing microbubble pharmaceuticals
US20140256970A1 (en) * 2011-09-30 2014-09-11 Ge Healthcare Limited Reactor for multi-step radiochemistry
JP6758065B2 (ja) * 2016-03-30 2020-09-23 日本メジフィジックス株式会社 放射性標識化合物の製造装置及び製造方法
CN113801173B (zh) * 2021-09-24 2024-03-12 上海安迪科正电子技术有限公司 一种氟-18标记的脱氧葡糖注射液的制备方法及应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2581558B1 (fr) * 1985-05-10 1987-06-26 Elf France Procede de traitement d'un carburant compose d'un melange d'hydrocarbures et d'alcools, et produit d'adsorption selective d'eau
GB0115927D0 (en) * 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase nucleophilic fluorination

Also Published As

Publication number Publication date
PT1817320E (pt) 2010-09-13
AU2005305624A1 (en) 2006-05-26
GB0425501D0 (en) 2004-12-22
CN101061130A (zh) 2007-10-24
RU2007115903A (ru) 2008-12-27
BRPI0518316A2 (pt) 2008-11-11
WO2006054098A2 (en) 2006-05-26
CA2584649C (en) 2013-09-24
CA2584649A1 (en) 2006-05-26
KR101267122B1 (ko) 2013-05-24
HK1107353A1 (en) 2008-04-03
NZ554613A (en) 2011-01-28
CN101061130B (zh) 2012-08-15
AU2005305624B2 (en) 2012-05-10
IL182740A0 (en) 2007-07-24
ATE472552T1 (de) 2010-07-15
ES2347165T3 (es) 2010-10-26
JP2008520636A (ja) 2008-06-19
KR20070084361A (ko) 2007-08-24
NO20073037L (no) 2007-08-16
WO2006054098A3 (en) 2006-08-03
DE602005022099D1 (de) 2010-08-12
EP1817320A2 (en) 2007-08-15
PL1817320T3 (pl) 2010-11-30
ZA200705015B (en) 2008-09-25
RU2394040C2 (ru) 2010-07-10
US20090076259A1 (en) 2009-03-19
JP5318416B2 (ja) 2013-10-16
EP1817320B1 (en) 2010-06-30

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