ZA200701056B - Multiparticulates of preferably an opioid, and method of manufacturing using extrusion - Google Patents
Multiparticulates of preferably an opioid, and method of manufacturing using extrusion Download PDFInfo
- Publication number
- ZA200701056B ZA200701056B ZA200701056A ZA200701056A ZA200701056B ZA 200701056 B ZA200701056 B ZA 200701056B ZA 200701056 A ZA200701056 A ZA 200701056A ZA 200701056 A ZA200701056 A ZA 200701056A ZA 200701056 B ZA200701056 B ZA 200701056B
- Authority
- ZA
- South Africa
- Prior art keywords
- multiparticulates
- oxycodone
- active agent
- pharmaceutically active
- unit dose
- Prior art date
Links
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Classifications
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
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- B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
- B29C48/03—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the shape of the extruded material at extrusion
- B29C48/04—Particle-shaped
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
- B29C48/25—Component parts, details or accessories; Auxiliary operations
- B29C48/36—Means for plasticising or homogenising the moulding material or forcing it through the nozzle or die
- B29C48/50—Details of extruders
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- B29C48/63—Screws having sections without mixing elements or threads, i.e. having cylinder shaped sections
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- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Mechanical Engineering (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0419296A GB2418854B (en) | 2004-08-31 | 2004-08-31 | Multiparticulates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200701056B true ZA200701056B (en) | 2008-07-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200701056A ZA200701056B (en) | 2004-08-31 | 2007-02-05 | Multiparticulates of preferably an opioid, and method of manufacturing using extrusion |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9259872B2 (de) |
| EP (2) | EP1809249A2 (de) |
| JP (3) | JP2008511604A (de) |
| KR (2) | KR101526779B1 (de) |
| CN (2) | CN103462904A (de) |
| AU (1) | AU2005278919B2 (de) |
| BR (1) | BRPI0514474B1 (de) |
| CA (1) | CA2576275C (de) |
| EA (1) | EA017435B1 (de) |
| GB (1) | GB2418854B (de) |
| IL (1) | IL180928A (de) |
| MX (1) | MX2007001904A (de) |
| NO (1) | NO20070871L (de) |
| NZ (1) | NZ552845A (de) |
| SG (1) | SG155880A1 (de) |
| WO (1) | WO2006024881A2 (de) |
| ZA (1) | ZA200701056B (de) |
Families Citing this family (47)
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| JP5870023B2 (ja) * | 2010-02-22 | 2016-02-24 | 第一三共株式会社 | 経口用徐放性固形製剤 |
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- 2005-08-31 KR KR1020137016849A patent/KR101526779B1/ko not_active IP Right Cessation
- 2005-08-31 SG SG200905776-1A patent/SG155880A1/en unknown
- 2005-08-31 EP EP05781628A patent/EP1809249A2/de not_active Withdrawn
- 2005-08-31 WO PCT/GB2005/050140 patent/WO2006024881A2/en active Application Filing
- 2005-08-31 KR KR1020077003915A patent/KR101306500B1/ko active IP Right Grant
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