ZA200610049B - Treatment with gemcitabine and an EGFR-inhibitor - Google Patents
Treatment with gemcitabine and an EGFR-inhibitor Download PDFInfo
- Publication number
- ZA200610049B ZA200610049B ZA200610049A ZA200610049A ZA200610049B ZA 200610049 B ZA200610049 B ZA 200610049B ZA 200610049 A ZA200610049 A ZA 200610049A ZA 200610049 A ZA200610049 A ZA 200610049A ZA 200610049 B ZA200610049 B ZA 200610049B
- Authority
- ZA
- South Africa
- Prior art keywords
- gemcitabine
- kinase inhibitor
- egfr kinase
- cancer
- erlotinib
- Prior art date
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- Molecular Biology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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US57654104P | 2004-06-03 | 2004-06-03 |
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ZA200610049B true ZA200610049B (en) | 2008-06-25 |
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ZA200610049A ZA200610049B (en) | 2004-06-03 | 2006-11-30 | Treatment with gemcitabine and an EGFR-inhibitor |
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US (1) | US20050272688A1 (ru) |
EP (1) | EP1755608A1 (ru) |
JP (1) | JP2008501652A (ru) |
KR (1) | KR100986945B1 (ru) |
CN (1) | CN1960732A (ru) |
AU (1) | AU2005249205A1 (ru) |
BR (1) | BRPI0511760A (ru) |
CA (1) | CA2567836A1 (ru) |
IL (1) | IL179525A0 (ru) |
MX (1) | MXPA06014015A (ru) |
NO (1) | NO20066056L (ru) |
NZ (1) | NZ551406A (ru) |
RU (1) | RU2006146619A (ru) |
WO (1) | WO2005117887A1 (ru) |
ZA (1) | ZA200610049B (ru) |
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JPWO2004080462A1 (ja) | 2003-03-10 | 2006-06-08 | エーザイ株式会社 | c−Kitキナーゼ阻害剤 |
CN100450998C (zh) | 2003-11-11 | 2009-01-14 | 卫材R&D管理有限公司 | 脲衍生物的制备方法 |
JP2008501651A (ja) * | 2004-06-03 | 2008-01-24 | エフ.ホフマン−ラ ロシュ アーゲー | イリノテカン(cpt−11)およびegfr阻害剤を用いた処置 |
SV2006002143A (es) * | 2004-06-16 | 2006-01-26 | Genentech Inc | Uso de un anticuerpo para el tratamiento del cancer resistente al platino |
JP4834553B2 (ja) | 2004-09-17 | 2011-12-14 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 医薬組成物 |
US20060084675A1 (en) * | 2004-10-18 | 2006-04-20 | Thomas Efferth | Combined treatment with artesunate and an epidermal growth factor receptor kinase inhibitor |
HUE038768T2 (hu) * | 2005-02-18 | 2018-11-28 | Abraxis Bioscience Llc | Terápiás szerek kombinációi, valamint beadásukra szolgáló módszerek, és kombinációs terápia |
US8735394B2 (en) | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
JP4989476B2 (ja) | 2005-08-02 | 2012-08-01 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 血管新生阻害物質の効果を検定する方法 |
CN101316590B (zh) | 2005-11-07 | 2011-08-03 | 卫材R&D管理有限公司 | 血管生成抑制剂和c-kit激酶抑制剂的组合使用 |
US20090247576A1 (en) * | 2005-11-22 | 2009-10-01 | Eisai R & D Management Co., Ltd. | Anti-tumor agent for multiple myeloma |
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RU2448708C3 (ru) * | 2006-05-18 | 2017-09-28 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Противоопухолевое средство против рака щитовидной железы |
US20070286864A1 (en) * | 2006-06-09 | 2007-12-13 | Buck Elizabeth A | Combined treatment with an EGFR kinase inhibitor and an agent that sensitizes tumor cells to the effects of EGFR kinase inhibitors |
WO2007146226A2 (en) * | 2006-06-09 | 2007-12-21 | Osi Pharmaceuticals, Inc. | Combined treatment with an egfr kinase inhibitor and an agent that sensitizes tumor cells to the effects of egfr kinase inhibitors |
JPWO2008001956A1 (ja) * | 2006-06-29 | 2009-12-03 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 肝線維症治療剤 |
JP5368096B2 (ja) | 2006-08-28 | 2013-12-18 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 未分化型胃癌に対する抗腫瘍剤 |
CN101616671A (zh) * | 2007-01-19 | 2009-12-30 | 卫材R&D管理有限公司 | 胰腺癌治疗用组合物 |
KR101445892B1 (ko) | 2007-01-29 | 2014-09-29 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 미분화형 위암 치료용 조성물 |
EP2181099A2 (en) * | 2007-08-23 | 2010-05-05 | Plus Chemicals S.A. | Crystalline forms of erlotinib hcl and formulations thereof |
TWI436775B (zh) * | 2007-08-24 | 2014-05-11 | Oncotherapy Science Inc | 以抗原胜肽合併化療藥劑治療胰臟癌 |
CA2704000C (en) | 2007-11-09 | 2016-12-13 | Eisai R&D Management Co., Ltd. | Combination of anti-angiogenic substance and anti-tumor platinum complex |
EP2236145B1 (en) | 2008-01-28 | 2014-05-14 | NanoCarrier Co., Ltd. | Pharmaceutical composition and combined agent |
US20100324087A1 (en) * | 2008-01-29 | 2010-12-23 | Eisai R&D Management Co., Ltd. | Combined use of angiogenesis inhibitor and taxane |
WO2010107960A1 (en) * | 2009-03-17 | 2010-09-23 | Brody Jonathan R | Methods for assessing the efficacy of gemcitabine or ara-c treatment of cancer using human antigen r levels |
AU2010212513B2 (en) * | 2009-10-02 | 2016-08-25 | Monash University | Ectopic pregnancy treatment |
US9012458B2 (en) | 2010-06-25 | 2015-04-21 | Eisai R&D Management Co., Ltd. | Antitumor agent using compounds having kinase inhibitory effect in combination |
CL2011000273A1 (es) | 2011-02-08 | 2011-06-17 | Univ Pontificia Catolica Chile | Uso de un inhibidor de la enzima fosfohidrolasa de acido fosfatidico (pap) o combinacion de inhibidores, en que el inhibidor es d(+) propranolol, y la combinacion es mezcla racemica de propranolol o d(+) propranolol junto con desipramina, para preparar un medicamento util en el tratamiento del cancer. |
CA2828946C (en) | 2011-04-18 | 2016-06-21 | Eisai R&D Management Co., Ltd. | Therapeutic agent for tumor |
ES2841809T3 (es) | 2011-06-03 | 2021-07-09 | Eisai R&D Man Co Ltd | Biomarcadores para pronosticar y evaluar el grado de respuesta de sujetos con cáncer de tiroides y de riñón a compuestos de lenvatinib |
WO2013006230A2 (en) * | 2011-07-01 | 2013-01-10 | Fox Chase Cancer Center | Combined inhibition of the vitamin d receptor and dna replication in the treatment of cancer |
US10350188B2 (en) | 2011-11-04 | 2019-07-16 | Myron R. Szewczuk | Use of Neu1 sialidase inhibitors in the treatment of cancer |
MX2015004979A (es) | 2012-12-21 | 2015-07-17 | Eisai R&D Man Co Ltd | Forma amorfa de derivado de quinolina y metodo para su produccion. |
AU2014266223B2 (en) | 2013-05-14 | 2020-06-25 | Eisai R&D Management Co., Ltd. | Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds |
PL3138555T3 (pl) | 2014-04-30 | 2021-04-06 | Fujifilm Corporation | Kompozycja liposomowa i sposób jej wytwarzania |
ES2926687T3 (es) | 2014-08-28 | 2022-10-27 | Eisai R&D Man Co Ltd | Derivado de quinolina muy puro y método para su producción |
US9889141B2 (en) | 2014-10-14 | 2018-02-13 | Institute For Cancer Research | Combined inhibition of the vitamin D receptor and poly(ADP) ribose polymerase (PARP) in the treatment of cancer |
HUE064614T2 (hu) | 2015-02-25 | 2024-04-28 | Eisai R&D Man Co Ltd | Eljárás egy kinolin-származék keserû ízének elnyomására |
KR102662228B1 (ko) | 2015-03-04 | 2024-05-02 | 머크 샤프 앤드 돔 코포레이션 | 암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합 |
AU2016279474B2 (en) | 2015-06-16 | 2021-09-09 | Eisai R&D Management Co., Ltd. | Anticancer agent |
US11395821B2 (en) | 2017-01-30 | 2022-07-26 | G1 Therapeutics, Inc. | Treatment of EGFR-driven cancer with fewer side effects |
JP7364561B2 (ja) * | 2018-06-20 | 2023-10-18 | 富士フイルム株式会社 | ゲムシタビンを内包するリポソーム組成物および免疫チェックポイント阻害剤を含む組合せ医薬 |
CN111773388B (zh) * | 2019-04-04 | 2023-07-18 | 上海奥奇医药科技有限公司 | A-失碳-5α雄甾烷化合物类药物与抗癌药物的联合应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
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US20030108545A1 (en) * | 1994-02-10 | 2003-06-12 | Patricia Rockwell | Combination methods of inhibiting tumor growth with a vascular endothelial growth factor receptor antagonist |
EE200100603A (et) * | 1999-05-14 | 2003-02-17 | Imclone Systems Incorporated | Inimese refraktaarsete kasvajate ravi epidermaalse kasvufaktori retseptori antagonistidega |
UA74803C2 (ru) * | 1999-11-11 | 2006-02-15 | Осі Фармасьютікалз, Інк. | Стойкий полиморф гидрохлорида n-(3-этинилфенил)-6,7-бис(2-метоксиэтокси)-4-хиназолинамина, способ его получения (варианты) и фармацевтическое применение |
WO2002039121A2 (en) * | 2000-11-03 | 2002-05-16 | Board Of Regents, The University Of Texas System | Methods for detecting the efficacy of anticancer treatments |
AU2002239486A1 (en) * | 2000-12-08 | 2002-06-18 | Uab Research Foundation | Combination radiation therapy and chemotherapy in conjuction with administration of growth factor receptor antibody |
PA8578001A1 (es) * | 2002-08-07 | 2004-05-07 | Warner Lambert Co | Combinaciones terapeuticas de inhibidores de quinasa de erb b y terapias antineoplasicas |
TW200501960A (en) * | 2002-10-02 | 2005-01-16 | Bristol Myers Squibb Co | Synergistic kits and compositions for treating cancer |
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2005
- 2005-05-27 RU RU2006146619/15A patent/RU2006146619A/ru unknown
- 2005-05-27 NZ NZ551406A patent/NZ551406A/en unknown
- 2005-05-27 KR KR1020067025451A patent/KR100986945B1/ko not_active IP Right Cessation
- 2005-05-27 CN CNA2005800179097A patent/CN1960732A/zh active Pending
- 2005-05-27 AU AU2005249205A patent/AU2005249205A1/en not_active Abandoned
- 2005-05-27 MX MXPA06014015A patent/MXPA06014015A/es active IP Right Grant
- 2005-05-27 EP EP05753110A patent/EP1755608A1/en not_active Withdrawn
- 2005-05-27 CA CA002567836A patent/CA2567836A1/en not_active Abandoned
- 2005-05-27 WO PCT/EP2005/005735 patent/WO2005117887A1/en active Application Filing
- 2005-05-27 JP JP2007513817A patent/JP2008501652A/ja active Pending
- 2005-05-27 BR BRPI0511760-7A patent/BRPI0511760A/pt not_active IP Right Cessation
- 2005-06-03 US US11/144,952 patent/US20050272688A1/en not_active Abandoned
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2006
- 2006-11-23 IL IL179525A patent/IL179525A0/en unknown
- 2006-11-30 ZA ZA200610049A patent/ZA200610049B/en unknown
- 2006-12-28 NO NO20066056A patent/NO20066056L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
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EP1755608A1 (en) | 2007-02-28 |
CA2567836A1 (en) | 2005-12-15 |
NZ551406A (en) | 2010-03-26 |
US20050272688A1 (en) | 2005-12-08 |
AU2005249205A1 (en) | 2005-12-15 |
CN1960732A (zh) | 2007-05-09 |
IL179525A0 (en) | 2007-07-04 |
RU2006146619A (ru) | 2008-07-20 |
MXPA06014015A (es) | 2007-02-08 |
NO20066056L (no) | 2007-01-25 |
WO2005117887A1 (en) | 2005-12-15 |
KR20070029736A (ko) | 2007-03-14 |
BRPI0511760A (pt) | 2008-01-08 |
KR100986945B1 (ko) | 2010-10-12 |
JP2008501652A (ja) | 2008-01-24 |
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