ZA200608714B - Formulation comprising histone deacetylase inhibitors - Google Patents
Formulation comprising histone deacetylase inhibitors Download PDFInfo
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- ZA200608714B ZA200608714B ZA200608714A ZA200608714A ZA200608714B ZA 200608714 B ZA200608714 B ZA 200608714B ZA 200608714 A ZA200608714 A ZA 200608714A ZA 200608714 A ZA200608714 A ZA 200608714A ZA 200608714 B ZA200608714 B ZA 200608714B
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- South Africa
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- pharmaceutical formulation
- cancer
- formulation according
- histone deacetylase
- deacetylase inhibitor
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04010333A EP1591109B1 (fr) | 2004-04-30 | 2004-04-30 | Formulation à libération biphasique comprenant un inhibiteur d'histone déacétylase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200608714B true ZA200608714B (en) | 2008-07-30 |
Family
ID=34924816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200608714A ZA200608714B (en) | 2004-04-30 | 2006-10-17 | Formulation comprising histone deacetylase inhibitors |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20070232528A1 (fr) |
| EP (1) | EP1591109B1 (fr) |
| JP (1) | JP4789927B2 (fr) |
| CN (1) | CN1980647B (fr) |
| AT (1) | ATE399539T1 (fr) |
| AU (1) | AU2005237251B2 (fr) |
| BR (1) | BRPI0509340A (fr) |
| CA (1) | CA2564877A1 (fr) |
| CY (1) | CY1108301T1 (fr) |
| DE (1) | DE602004014723D1 (fr) |
| DK (1) | DK1591109T3 (fr) |
| ES (1) | ES2308065T3 (fr) |
| MX (1) | MXPA06012568A (fr) |
| NZ (1) | NZ550879A (fr) |
| PL (1) | PL1591109T3 (fr) |
| PT (1) | PT1591109E (fr) |
| SI (1) | SI1591109T1 (fr) |
| WO (1) | WO2005105055A1 (fr) |
| ZA (1) | ZA200608714B (fr) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2324426A1 (fr) | 1998-02-11 | 1999-08-19 | Douglas V. Faller | Compositions et techniques de traitement de la mucoviscidose |
| EP1855760A2 (fr) | 2005-02-03 | 2007-11-21 | TopoTarget UK Limited | Polytherapies faisant appel a des inhibiteurs de hdac |
| PL1901729T3 (pl) * | 2005-05-13 | 2012-07-31 | Topotarget Uk Ltd | Formulacje farmaceutyczne inhibitorów hdac |
| EP1915141A1 (fr) * | 2005-08-10 | 2008-04-30 | Novartis AG | Procede d'utilisation d'inhibiteurs de la desacetylase |
| AU2006313517B2 (en) * | 2005-11-10 | 2013-06-27 | Topotarget Uk Limited | Histone deacetylase (HDAC) inhibitors (PXD101) for the treatment of cancer alone or in combination with chemotherapeutic agent |
| BRPI0520686A2 (pt) * | 2005-11-16 | 2009-05-19 | Univ Mexico Nacional Autonoma | uso de agentes modificantes de transcriptoma associado a quimioterapia ou radioterapia contra o cáncer |
| US20070207950A1 (en) * | 2005-12-21 | 2007-09-06 | Duke University | Methods and compositions for regulating HDAC6 activity |
| DE102006006532B4 (de) | 2006-02-10 | 2007-11-08 | Biogenerics Pharma Gmbh | Pharmazeutische Zubereitung |
| EP1839656A1 (fr) * | 2006-03-31 | 2007-10-03 | TopoTarget Germany AG | Utilisation d'acide valproic pour le traitement topique de doux de modérer vulgaris d'acné |
| WO2008013589A2 (fr) | 2006-04-24 | 2008-01-31 | Gloucester Pharmaceuticals | Traitement de tumeurs exprimant ras |
| US8957027B2 (en) | 2006-06-08 | 2015-02-17 | Celgene Corporation | Deacetylase inhibitor therapy |
| WO2008027837A2 (fr) * | 2006-08-28 | 2008-03-06 | The Regents Of The University Of California | Potentialisateur de petite molécule utilisé en hormonothérapie pour le cancer du sein |
| US8088951B2 (en) * | 2006-11-30 | 2012-01-03 | Massachusetts Institute Of Technology | Epigenetic mechanisms re-establish access to long-term memory after neuronal loss |
| CA2671649A1 (fr) * | 2006-12-06 | 2008-06-12 | Sapporo Medical University | Potentialisation d'immunite cellulaire au moyen d'inhibiteurs d'histone desacetylase (hdac) |
| ES2529147T3 (es) * | 2006-12-26 | 2015-02-17 | Pharmacyclics, Inc. | Método para usar los inhibidores de la histona deacetilasa y monitorear biomarcadores en la terapia de combinación |
| WO2008083288A2 (fr) | 2006-12-29 | 2008-07-10 | Gloucester Pharmaceuticals | Préparation de la romidepsine |
| CA2574531C (fr) * | 2007-01-19 | 2016-10-25 | The University Of British Columbia | Promoteurs de l'acetylation d'hat et utilisations de compositions contenant ceux-ci pour promouvoir l'immunogenicite |
| WO2008090534A1 (fr) * | 2007-01-26 | 2008-07-31 | Berand Limited | Procédés et compositions destinés à l'inhibition d'un gain de poids excessif, la réduction de comportements alimentaires inappropriés et l'inhibition de l'hyperphagie pour le traitement de l'obésité |
| US20100093611A1 (en) * | 2007-05-16 | 2010-04-15 | Horrigan Stephen K | Compounds and methods for treating or preventing autoimmune diseases |
| EP2203421B1 (fr) * | 2007-09-25 | 2014-05-07 | TopoTarget UK Limited | Procédés de synthèse de certains composés n-hydroxy-3-(3-phenylsulfamoyl-phenyl)-acrylamides |
| MX2010009642A (es) * | 2008-03-07 | 2010-09-22 | Topotarget As | Metodos de tratamiento utilizando infusion continua prolongada de belinostat. |
| DE102008047515A1 (de) * | 2008-09-12 | 2010-03-25 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Behandlung einer demyelinisierenden Erkrankung |
| GB0900555D0 (en) * | 2009-01-14 | 2009-02-11 | Topotarget As | New methods |
| WO2011038110A2 (fr) * | 2009-09-23 | 2011-03-31 | The General Hospital Corporation | Méthodes de traitement des maladies métaboliques |
| WO2011038224A1 (fr) | 2009-09-24 | 2011-03-31 | Trustees Of Boston University | Procédés pour le traitement de troubles viraux |
| AU2010313255B2 (en) * | 2009-10-30 | 2015-04-30 | Massachusetts Institute Of Technology | The use of CI-994 and dinaline for the treatment of memory/cognition and anxiety disorders |
| WO2011063164A2 (fr) * | 2009-11-18 | 2011-05-26 | Steady Sleep Rx Co., Inc. | Médicaments de cannabinoïde à libération prolongée |
| EP2509418A4 (fr) * | 2009-12-08 | 2013-03-20 | Hemaquest Pharmaceuticals Inc | Procédés et régimes à faible dose pour traiter des troubles des globules rouges |
| WO2011113013A2 (fr) | 2010-03-11 | 2011-09-15 | Hemaquest Pharmaceuticals, Inc. | Procédés et compositions pour le traitement d'états viraux ou induits par des virus |
| RU2607634C2 (ru) | 2010-07-12 | 2017-01-10 | Селджин Корпорейшн | Твердые формы ромидепсина и их применение |
| US8859502B2 (en) | 2010-09-13 | 2014-10-14 | Celgene Corporation | Therapy for MLL-rearranged leukemia |
| US9018176B2 (en) * | 2010-12-02 | 2015-04-28 | Susan Perrine | Inducers of hematopoiesis and fetal globin production for treatment of cytopenias and hemoglobin disorders |
| ES2842970T3 (es) | 2011-03-09 | 2021-07-15 | Cereno Scient Ab | Compuestos y métodos para mejorar la fibrinólisis endógena alterada usando inhibidores de la histona desacetilasa |
| UA110853C2 (uk) | 2011-09-13 | 2016-02-25 | Фармасайклікс, Інк. | Лікарські форми інгібітора гістондеацетилази у комбінації з бендамустином та їхнє застосування |
| WO2013039956A2 (fr) * | 2011-09-14 | 2013-03-21 | The Trustees Of Columbia University In The City Of New York | Compositions et méthodes de traitement de troubles de l'humeur |
| AU2013202506B2 (en) | 2012-09-07 | 2015-06-18 | Celgene Corporation | Resistance biomarkers for hdac inhibitors |
| AU2013202507B9 (en) | 2012-11-14 | 2015-08-13 | Celgene Corporation | Inhibition of drug resistant cancer cells |
| NZ630311A (en) | 2013-12-27 | 2016-03-31 | Celgene Corp | Romidepsin formulations and uses thereof |
| GB201417828D0 (en) | 2014-10-08 | 2014-11-19 | Cereno Scient Ab | New methods and compositions |
| FR3025105B1 (fr) * | 2014-09-02 | 2018-03-02 | Centre Hospitalier Universitaire Pontchaillou | Utilisation de l'acide valproique ou de ses derives dans le traitement des insuffisances en hepcidine et de leurs consequences |
| KR20220100077A (ko) * | 2016-04-21 | 2022-07-14 | 발큐리아 에이비 | 암의 예비치료용 조성물 및 방법 |
| WO2017192458A1 (fr) * | 2016-05-03 | 2017-11-09 | Spectrix Therapeutics, LLC | Compositions et méthodes permettant d'apporter de l'hormone thyroïdienne ou des analogues de celle-ci |
| KR20200045496A (ko) | 2017-08-29 | 2020-05-04 | 콘리그 파마 에이피에스 | 수플라타스트 토실레이트를 포함하는 조성물 |
| CN109705057B (zh) * | 2017-10-25 | 2023-05-30 | 成都先导药物开发股份有限公司 | 组蛋白去乙酰化酶抑制剂及其制备方法与用途 |
| CN108992442A (zh) * | 2018-07-12 | 2018-12-14 | 上海交通大学医学院附属瑞金医院 | Ms-275在制备促进胰岛素分泌药物中的用途 |
| CN110882250B (zh) * | 2018-09-07 | 2022-09-13 | 上海市生物医药技术研究院 | Scriptaid在制备治疗弱精症药物和试剂及器械器皿中的应用 |
| EP3976198A4 (fr) | 2019-05-31 | 2023-07-19 | Viracta Subsidiary, Inc. | Méthodes de traitement de cancers associés à un virus avec des inhibiteurs d'histone désacétylase |
| CN110652506A (zh) * | 2019-11-09 | 2020-01-07 | 福建医科大学附属第一医院 | 三醋酸甘油酯在制备预防和治疗抑郁症药物中的用途 |
| CN111358777A (zh) * | 2020-02-24 | 2020-07-03 | 军事科学院军事医学研究院环境医学与作业医学研究所 | 一种提高外周血单个核细胞线粒体功能的方法和应用 |
| US20230332155A1 (en) * | 2020-06-30 | 2023-10-19 | Korea University Research And Business Foundation | Pharmaceutical composition containing sirt7 inhibitor for preventing or treating allergic diseases |
| CN112998101A (zh) * | 2021-04-20 | 2021-06-22 | 上海舒泽生物科技研究所 | 一种人体衰老kat7基因的抑制剂固体饮料及其制备方法 |
| CN114306259B (zh) * | 2021-11-18 | 2023-06-06 | 江苏宇锐医药科技有限公司 | 一种丙戊酸钠双层缓释片及其制备方法 |
| CN115094142B (zh) * | 2022-07-19 | 2024-05-28 | 中国医学科学院肿瘤医院 | 用于诊断肺肠型腺癌的甲基化标志物 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK152744C (da) * | 1982-08-13 | 1988-10-31 | Benzon As Alfred | Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat |
| IT1215726B (it) * | 1988-01-18 | 1990-02-22 | Alfa Wassermann Spa | Formulazioni galeniche a cessione programmata. |
| IL96311A (en) * | 1989-12-01 | 1995-05-26 | Abbott Lab | Medications with delayed release |
| IT1255522B (it) * | 1992-09-24 | 1995-11-09 | Ubaldo Conte | Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita' |
| US6287598B1 (en) * | 1993-05-28 | 2001-09-11 | Alza Corporation | Method for providing sustained antiepileptic therapy |
| FR2772615B1 (fr) * | 1997-12-23 | 2002-06-14 | Lipha | Comprime multicouche pour la liberation instantanee puis prolongee de substances actives |
| US6419960B1 (en) * | 1998-12-17 | 2002-07-16 | Euro-Celtique S.A. | Controlled release formulations having rapid onset and rapid decline of effective plasma drug concentrations |
| BR0007360A (pt) * | 1999-12-23 | 2001-08-14 | Johnson & Johnson | Composição de liberação controlada |
| EP1170008A1 (fr) * | 2000-07-07 | 2002-01-09 | Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus | Acide valproique et ses dérivés en tant qu' inhibiteurs de la déacétylase de l' histone |
| JP4632166B2 (ja) * | 2001-01-31 | 2011-02-16 | 日本ポリウレタン工業株式会社 | リグノセルロース系熱圧成形体用接着剤組成物、及びそれを用いた熱圧成形体の製造方法 |
-
2004
- 2004-04-30 PL PL04010333T patent/PL1591109T3/pl unknown
- 2004-04-30 ES ES04010333T patent/ES2308065T3/es not_active Expired - Lifetime
- 2004-04-30 PT PT04010333T patent/PT1591109E/pt unknown
- 2004-04-30 DE DE602004014723T patent/DE602004014723D1/de not_active Expired - Lifetime
- 2004-04-30 DK DK04010333T patent/DK1591109T3/da active
- 2004-04-30 EP EP04010333A patent/EP1591109B1/fr not_active Expired - Lifetime
- 2004-04-30 AT AT04010333T patent/ATE399539T1/de active
- 2004-04-30 SI SI200430820T patent/SI1591109T1/sl unknown
-
2005
- 2005-05-02 NZ NZ550879A patent/NZ550879A/en unknown
- 2005-05-02 BR BRPI0509340-6A patent/BRPI0509340A/pt not_active IP Right Cessation
- 2005-05-02 CA CA002564877A patent/CA2564877A1/fr not_active Abandoned
- 2005-05-02 CN CN2005800223047A patent/CN1980647B/zh not_active Expired - Fee Related
- 2005-05-02 WO PCT/EP2005/004739 patent/WO2005105055A1/fr active Application Filing
- 2005-05-02 MX MXPA06012568A patent/MXPA06012568A/es active IP Right Grant
- 2005-05-02 AU AU2005237251A patent/AU2005237251B2/en not_active Ceased
- 2005-05-02 JP JP2007509993A patent/JP4789927B2/ja not_active Expired - Fee Related
- 2005-05-02 US US11/587,979 patent/US20070232528A1/en not_active Abandoned
-
2006
- 2006-10-17 ZA ZA200608714A patent/ZA200608714B/en unknown
-
2008
- 2008-08-28 CY CY20081100925T patent/CY1108301T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1591109A1 (fr) | 2005-11-02 |
| DE602004014723D1 (de) | 2008-08-14 |
| PL1591109T3 (pl) | 2008-11-28 |
| AU2005237251B2 (en) | 2010-11-04 |
| SI1591109T1 (sl) | 2008-10-31 |
| BRPI0509340A (pt) | 2007-09-18 |
| DK1591109T3 (da) | 2008-10-06 |
| US20070232528A1 (en) | 2007-10-04 |
| MXPA06012568A (es) | 2007-04-30 |
| JP2007535518A (ja) | 2007-12-06 |
| NZ550879A (en) | 2010-05-28 |
| ATE399539T1 (de) | 2008-07-15 |
| WO2005105055A1 (fr) | 2005-11-10 |
| CN1980647A (zh) | 2007-06-13 |
| AU2005237251A1 (en) | 2005-11-10 |
| CN1980647B (zh) | 2010-08-18 |
| JP4789927B2 (ja) | 2011-10-12 |
| EP1591109B1 (fr) | 2008-07-02 |
| CA2564877A1 (fr) | 2005-11-10 |
| PT1591109E (pt) | 2008-09-05 |
| CY1108301T1 (el) | 2014-02-12 |
| ES2308065T3 (es) | 2008-12-01 |
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