ZA200604875B - 3-Cycloalkylaminopyrrotidine derivatives as modulators of chemokine receptors - Google Patents

3-Cycloalkylaminopyrrotidine derivatives as modulators of chemokine receptors

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Publication number
ZA200604875B
ZA200604875B ZA200604875A ZA200604875A ZA200604875B ZA 200604875 B ZA200604875 B ZA 200604875B ZA 200604875 A ZA200604875 A ZA 200604875A ZA 200604875 A ZA200604875 A ZA 200604875A ZA 200604875 B ZA200604875 B ZA 200604875B
Authority
ZA
South Africa
Prior art keywords
cycloalkylaminopyrrotidine
modulators
derivatives
chemokine receptors
chemokine
Prior art date
Application number
ZA200604875A
Other languages
English (en)
Inventor
Xue Chu-Biao
Han Amy Qi
Zheng Changshen
Zhang Yingxin
Metcalf Brian
Darius J Robinson
Wang Anlai
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of ZA200604875B publication Critical patent/ZA200604875B/xx

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    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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ZA200604875A 2003-12-18 2006-06-13 3-Cycloalkylaminopyrrotidine derivatives as modulators of chemokine receptors ZA200604875B (en)

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Publication number Priority date Publication date Assignee Title
EA010027B1 (ru) 2002-11-27 2008-06-30 Инсайт Корпорейшн Производные 3-аминопирролидина в качестве модуляторов рецепторов хемокинов
GEP20094680B (en) 2004-04-13 2009-05-10 Incyte Corp Piperazinylpiperidine derivatives as chemokine receptor antagonists
JP2007537264A (ja) 2004-05-11 2007-12-20 インサイト コーポレイション ケモカインレセプタのモジュレータとしての３−（４−ヘテロアリールシクロヘキシルアミノ）シクロペンタンカルボキサミド
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