ZA200604638B - Inhibitors of hepatitis C virus NS3/NS4A serine protease - Google Patents
Inhibitors of hepatitis C virus NS3/NS4A serine protease Download PDFInfo
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- ZA200604638B ZA200604638B ZA200604638A ZA200604638A ZA200604638B ZA 200604638 B ZA200604638 B ZA 200604638B ZA 200604638 A ZA200604638 A ZA 200604638A ZA 200604638 A ZA200604638 A ZA 200604638A ZA 200604638 B ZA200604638 B ZA 200604638B
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
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US52884503P | 2003-12-11 | 2003-12-11 |
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ZA200604638A ZA200604638B (en) | 2003-12-11 | 2006-06-06 | Inhibitors of hepatitis C virus NS3/NS4A serine protease |
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US (1) | US7485625B2 (fr) |
EP (1) | EP1742913A1 (fr) |
JP (1) | JP2007513971A (fr) |
KR (1) | KR20060118532A (fr) |
CN (1) | CN100509784C (fr) |
AR (1) | AR046758A1 (fr) |
AU (1) | AU2004298498B2 (fr) |
BR (1) | BRPI0416902A (fr) |
CA (1) | CA2549167A1 (fr) |
CO (1) | CO5700736A2 (fr) |
EC (1) | ECSP066626A (fr) |
IL (1) | IL176237A0 (fr) |
NO (1) | NO20063205L (fr) |
PE (1) | PE20050940A1 (fr) |
RU (1) | RU2006124594A (fr) |
TW (1) | TW200518746A (fr) |
WO (1) | WO2005058821A1 (fr) |
ZA (1) | ZA200604638B (fr) |
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US3216325A (en) * | 1962-04-16 | 1965-11-09 | Dole Valve Co | Pneumatic control system |
IL152022A0 (en) | 2000-04-03 | 2003-04-10 | Vertex Pharma | Compounds useful as protease inhibitors and pharmaceutical compositions containing the same |
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AU2001276988B2 (en) * | 2000-07-21 | 2007-01-25 | Dendreon Corporation | Peptides as NS3-serine protease inhibitors of hepatitis C virus |
SV2003000617A (es) | 2000-08-31 | 2003-01-13 | Lilly Co Eli | Inhibidores de la proteasa peptidomimetica ref. x-14912m |
WO2002048172A2 (fr) * | 2000-12-12 | 2002-06-20 | Schering Corporation | Peptides diaryliques utilises comme inhibiteurs de ns3-serine protease du virus de l'hepatite c |
MXPA04007163A (es) | 2002-01-23 | 2004-10-29 | Schering Corp | Compuestos de prolina como inhibidores de la proteasa serina ns3 para utilizarse en el tratamiento de la infeccion por el virus de la hepatitis c. |
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2004
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- 2004-12-09 CN CNB2004800367937A patent/CN100509784C/zh not_active Expired - Fee Related
- 2004-12-09 US US11/007,910 patent/US7485625B2/en not_active Expired - Fee Related
- 2004-12-09 BR BRPI0416902-6A patent/BRPI0416902A/pt not_active IP Right Cessation
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- 2004-12-09 PE PE2004001217A patent/PE20050940A1/es not_active Application Discontinuation
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- 2004-12-09 KR KR1020067011224A patent/KR20060118532A/ko not_active Application Discontinuation
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- 2006-06-11 IL IL176237A patent/IL176237A0/en unknown
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AR046758A1 (es) | 2005-12-21 |
KR20060118532A (ko) | 2006-11-23 |
AU2004298498B2 (en) | 2008-09-11 |
US7485625B2 (en) | 2009-02-03 |
EP1742913A1 (fr) | 2007-01-17 |
CN1890215A (zh) | 2007-01-03 |
RU2006124594A (ru) | 2008-01-27 |
NO20063205L (no) | 2006-09-08 |
CN100509784C (zh) | 2009-07-08 |
TW200518746A (en) | 2005-06-16 |
JP2007513971A (ja) | 2007-05-31 |
BRPI0416902A (pt) | 2007-01-16 |
CA2549167A1 (fr) | 2005-06-30 |
US20050153900A1 (en) | 2005-07-14 |
PE20050940A1 (es) | 2005-11-08 |
IL176237A0 (en) | 2006-10-05 |
AU2004298498A1 (en) | 2005-06-30 |
WO2005058821A1 (fr) | 2005-06-30 |
ECSP066626A (es) | 2006-10-25 |
CO5700736A2 (es) | 2006-11-30 |
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