ZA200602262B - 2-Pyridone derivatives as neutrophil elastase inhibitors and their use - Google Patents

2-Pyridone derivatives as neutrophil elastase inhibitors and their use

Info

Publication number
ZA200602262B
ZA200602262B ZA200602262A ZA200602262A ZA200602262B ZA 200602262 B ZA200602262 B ZA 200602262B ZA 200602262 A ZA200602262 A ZA 200602262A ZA 200602262 A ZA200602262 A ZA 200602262A ZA 200602262 B ZA200602262 B ZA 200602262B
Authority
ZA
South Africa
Prior art keywords
neutrophil elastase
elastase inhibitors
pyridone derivatives
pyridone
derivatives
Prior art date
Application number
ZA200602262A
Other languages
English (en)
Inventor
Hansen Peter
Loenn Hans
Lawitz Karolina
Nikitidis Antonios
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29212489&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200602262(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ZA200602262B publication Critical patent/ZA200602262B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ZA200602262A 2003-09-18 2006-03-17 2-Pyridone derivatives as neutrophil elastase inhibitors and their use ZA200602262B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0302487A SE0302487D0 (sv) 2003-09-18 2003-09-18 Novel compounds

Publications (1)

Publication Number Publication Date
ZA200602262B true ZA200602262B (en) 2007-07-25

Family

ID=29212489

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200602262A ZA200602262B (en) 2003-09-18 2006-03-17 2-Pyridone derivatives as neutrophil elastase inhibitors and their use

Country Status (25)

Country Link
US (1) US20070043036A1 (index.php)
EP (1) EP1663974B1 (index.php)
JP (1) JP2007505902A (index.php)
KR (1) KR20060096995A (index.php)
CN (1) CN100439339C (index.php)
AR (1) AR046083A1 (index.php)
AT (1) ATE420861T1 (index.php)
AU (1) AU2004272485B2 (index.php)
BR (1) BRPI0414570A (index.php)
CA (1) CA2538410A1 (index.php)
CO (1) CO5670357A2 (index.php)
DE (1) DE602004019110D1 (index.php)
ES (1) ES2319300T3 (index.php)
IL (1) IL173986A0 (index.php)
IS (1) IS8394A (index.php)
MX (1) MXPA06002723A (index.php)
NO (1) NO20061700L (index.php)
RU (1) RU2348617C2 (index.php)
SA (1) SA04250300B1 (index.php)
SE (1) SE0302487D0 (index.php)
TW (1) TW200526579A (index.php)
UA (1) UA84878C2 (index.php)
UY (1) UY28513A1 (index.php)
WO (1) WO2005026124A1 (index.php)
ZA (1) ZA200602262B (index.php)

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Also Published As

Publication number Publication date
IS8394A (is) 2006-03-31
NO20061700L (no) 2006-04-18
WO2005026124A1 (en) 2005-03-24
US20070043036A1 (en) 2007-02-22
IL173986A0 (en) 2006-07-05
JP2007505902A (ja) 2007-03-15
CN1856467A (zh) 2006-11-01
TW200526579A (en) 2005-08-16
HK1089167A1 (en) 2006-11-24
KR20060096995A (ko) 2006-09-13
CN100439339C (zh) 2008-12-03
MXPA06002723A (es) 2006-06-06
RU2348617C2 (ru) 2009-03-10
AR046083A1 (es) 2005-11-23
CO5670357A2 (es) 2006-08-31
BRPI0414570A (pt) 2006-11-07
SA04250300B1 (ar) 2008-09-07
RU2006112427A (ru) 2007-11-10
ES2319300T3 (es) 2009-05-06
UA84878C2 (ru) 2008-12-10
ATE420861T1 (de) 2009-01-15
DE602004019110D1 (de) 2009-03-05
CA2538410A1 (en) 2005-03-24
UY28513A1 (es) 2005-04-29
EP1663974A1 (en) 2006-06-07
AU2004272485A1 (en) 2005-03-24
EP1663974B1 (en) 2009-01-14
SE0302487D0 (sv) 2003-09-18
AU2004272485B2 (en) 2008-03-13

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