ZA200508623B - Use of derivatives of 2,4-dihydro-[1,2,4]triazole-3-thione as inhibitors of the enzyme myeloperoxidase (MPO) - Google Patents

Use of derivatives of 2,4-dihydro-[1,2,4]triazole-3-thione as inhibitors of the enzyme myeloperoxidase (MPO) Download PDF

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ZA200508623B
ZA200508623B ZA200508623A ZA200508623A ZA200508623B ZA 200508623 B ZA200508623 B ZA 200508623B ZA 200508623 A ZA200508623 A ZA 200508623A ZA 200508623 A ZA200508623 A ZA 200508623A ZA 200508623 B ZA200508623 B ZA 200508623B
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thione
dihydro
triazole
phenyl
chlorobenzyl
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ZA200508623A
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English (en)
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Svensson Mats
Turek Dominika
Tidun Anna-Karin
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Astrazeneca Ab
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Publication of ZA200508623B publication Critical patent/ZA200508623B/en

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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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ZA200508623A 2003-04-25 2005-10-24 Use of derivatives of 2,4-dihydro-[1,2,4]triazole-3-thione as inhibitors of the enzyme myeloperoxidase (MPO) ZA200508623B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0301232A SE0301232D0 (sv) 2003-04-25 2003-04-25 Novel use

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ZA200508623B true ZA200508623B (en) 2007-07-25

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ZA200508623A ZA200508623B (en) 2003-04-25 2005-10-24 Use of derivatives of 2,4-dihydro-[1,2,4]triazole-3-thione as inhibitors of the enzyme myeloperoxidase (MPO)

Country Status (13)

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US (1) US20070093483A1 (es)
EP (1) EP1620410A1 (es)
JP (1) JP2006524686A (es)
KR (1) KR20060006064A (es)
CN (1) CN1780822A (es)
AU (1) AU2004234320A1 (es)
BR (1) BRPI0409498A (es)
CA (1) CA2523020A1 (es)
MX (1) MXPA05011207A (es)
NO (1) NO20055565L (es)
SE (1) SE0301232D0 (es)
WO (1) WO2004096781A1 (es)
ZA (1) ZA200508623B (es)

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SE0302756D0 (sv) * 2003-10-17 2003-10-17 Astrazeneca Ab Novel Compounds
SE0402591D0 (sv) * 2004-10-25 2004-10-25 Astrazeneca Ab Novel use
JP4954083B2 (ja) 2004-11-18 2012-06-13 シンタ ファーマスーティカルズ コーポレイション Ｈｓｐ９０活性を調節するトリアゾール化合物
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CN101723909B (zh) * 2008-10-29 2011-12-28 天津药物研究院 三唑酮类化合物、其制备方法和用途
WO2011133581A1 (en) 2010-04-19 2011-10-27 General Atomics Methods and compositions for assaying enzymatic activity of myeloperoxidase in blood samples
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JP2014532712A (ja) 2011-11-02 2014-12-08 シンタ ファーマシューティカルズ コーポレーション トポイソメラーゼｉ阻害剤とｈｓｐ９０阻害剤の組合せを使用する癌療法
US20140286902A1 (en) 2011-11-02 2014-09-25 Synta Pharmaceuticals Corp. Combination therapy of hsp90 inhibitors with platinum-containing agents
JP5731718B2 (ja) * 2011-11-11 2015-06-10 ファイザー・インク ２−チオピリミジノン
EP2780010A1 (en) 2011-11-14 2014-09-24 Synta Pharmaceuticals Corp. Combination therapy of hsp90 inhibitors with braf inhibitors
FR2988000A1 (fr) * 2012-03-16 2013-09-20 Thomas Wandji Composition pharmaceutique active dans la therapie des affections virales humaines et animales
MX2020004202A (es) * 2017-10-30 2020-08-13 Neuropore Therapies Inc Fenil sulfonil fenil triazol tionas sustituidas y usos de las mismas.
KR20200083843A (ko) 2018-12-31 2020-07-09 공주대학교 산학협력단 4-(2-플루오로페닐)-3-(3-메톡시벤질)-1h-1,2,4-트리아졸-5(4h)-온 및 이의 퇴행성 뇌질환 및 대사성 질환 치료제로서의 용도
CN110313401A (zh) * 2019-07-12 2019-10-11 华南农业大学 一种促进企剑白墨墨兰组织培养过程中芽分化的方法
US20230192702A1 (en) * 2020-05-06 2023-06-22 Biohaven Therapeutics Ltd. Process for the preparation of verdiperstat
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MXPA05011207A (es) 2005-12-14
AU2004234320A1 (en) 2004-11-11
CA2523020A1 (en) 2004-11-11
JP2006524686A (ja) 2006-11-02
WO2004096781A1 (en) 2004-11-11
EP1620410A1 (en) 2006-02-01
NO20055565D0 (no) 2005-11-24
NO20055565L (no) 2006-01-25
US20070093483A1 (en) 2007-04-26
SE0301232D0 (sv) 2003-04-25
KR20060006064A (ko) 2006-01-18
CN1780822A (zh) 2006-05-31
BRPI0409498A (pt) 2006-05-02

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Publication Publication Date Title
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