ZA200505306B - Complexes of protein crystals and ionic polymers - Google Patents

Complexes of protein crystals and ionic polymers Download PDF

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Publication number
ZA200505306B
ZA200505306B ZA200505306A ZA200505306A ZA200505306B ZA 200505306 B ZA200505306 B ZA 200505306B ZA 200505306 A ZA200505306 A ZA 200505306A ZA 200505306 A ZA200505306 A ZA 200505306A ZA 200505306 B ZA200505306 B ZA 200505306B
Authority
ZA
South Africa
Prior art keywords
protein
group
complex
composition
solution
Prior art date
Application number
ZA200505306A
Other languages
English (en)
Inventor
Nazer Khalaf
Chandrika Govardhan
Original Assignee
Altus Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altus Pharmaceuticals Inc filed Critical Altus Pharmaceuticals Inc
Publication of ZA200505306B publication Critical patent/ZA200505306B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K17/00Carrier-bound or immobilised peptides; Preparation thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2299/00Coordinates from 3D structures of peptides, e.g. proteins or enzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
ZA200505306A 2002-12-31 2003-12-31 Complexes of protein crystals and ionic polymers ZA200505306B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43777502P 2002-12-31 2002-12-31

Publications (1)

Publication Number Publication Date
ZA200505306B true ZA200505306B (en) 2006-09-27

Family

ID=32713227

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200505306A ZA200505306B (en) 2002-12-31 2003-12-31 Complexes of protein crystals and ionic polymers

Country Status (12)

Country Link
US (1) US20060008532A1 (fr)
EP (1) EP1585771A4 (fr)
JP (2) JP2006523609A (fr)
KR (1) KR20050094832A (fr)
AU (1) AU2003300126B2 (fr)
BR (1) BR0317896A (fr)
CA (1) CA2512001A1 (fr)
CO (1) CO5640146A2 (fr)
MX (1) MXPA05007182A (fr)
NZ (2) NZ571243A (fr)
WO (1) WO2004060920A1 (fr)
ZA (1) ZA200505306B (fr)

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US20070160622A1 (en) * 2005-12-07 2007-07-12 Medivas, Llc Method for assembling a polymer-biologic delivery composition
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CA2610159C (fr) * 2005-06-10 2015-03-31 Altus Pharmaceuticals Inc. Procede de reduction de la teneur en oxalate par administration de cristaux d'oxalate oxydase
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CA2623198C (fr) 2005-09-22 2014-08-05 Medivas, Llc Formules de poly(ester amide) et de poly(ester urethane) contenant des diesters de bis-(a-amino)-diol et methodes d'emploi
EP1933881B1 (fr) * 2005-09-22 2019-03-13 Medivas, LLC Compositions polymères solides pour administration et méthodes d'utilisation de celles-ci
JP2009514900A (ja) * 2005-11-04 2009-04-09 スミスクライン・ビーチャム・コーポレイション 血糖降下剤の投与方法
CA2670355A1 (fr) * 2005-11-21 2008-04-24 Medivas, Llc Particules polymeriques pour administration de macromolecules et procedes d'utilisation
JP2009521486A (ja) * 2005-12-23 2009-06-04 アルタス ファーマシューティカルズ インコーポレイテッド ポリカチオン錯化タンパク質結晶を含む組成物およびこれを使用した治療法
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WO2007133616A2 (fr) * 2006-05-09 2007-11-22 Medivas, Llc Polymères hydrosolubles biodégradables
MX2009001226A (es) 2006-08-04 2009-03-20 Baxter Int Composicion basada en microesferas para prevenir y/o revertir la diabetes autoinmune de nuevo inicio.
US8071544B2 (en) 2006-12-18 2011-12-06 Althea Technologies, Inc. Crystallized recombinant human growth factor formulations
EP2120859B1 (fr) * 2006-12-21 2013-11-20 Stryker Corporation Formulations à libération entretenue comprenant des cristaux de bmp-7
US20080299228A1 (en) * 2007-05-29 2008-12-04 Alan Gerald Harris Topical compositions comprising a macromolecule and methods of using same
US20090029937A1 (en) * 2007-07-24 2009-01-29 Cornell University Biodegradable cationic polymer gene transfer compositions and methods of use
PT2215117E (pt) 2007-10-30 2015-04-01 Genentech Inc Purificação de anticorpo por cromatografia de troca de catiões
US20110171268A1 (en) * 2008-03-24 2011-07-14 Althea Technologies, Inc. Uricase compositions and methods of use
EP2323671A4 (fr) * 2008-08-13 2012-09-26 Medivas Llc Polymères biodégradables à base d aabb-poly(depsipeptides) et procédés d utilisation
US8323685B2 (en) 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing compositions containing microparticles
US8367427B2 (en) 2008-08-20 2013-02-05 Baxter International Inc. Methods of processing compositions containing microparticles
US8323615B2 (en) 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing multi-phasic dispersions
JP5119232B2 (ja) * 2009-11-06 2013-01-16 株式会社マルハニチロ食品 プロタミンの定量法
JP5808082B2 (ja) * 2010-04-30 2015-11-10 株式会社Adeka 細胞への水溶性高分子量物質の導入方法及び導入剤
JP5703617B2 (ja) * 2010-07-23 2015-04-22 ライオン株式会社 口臭消臭製剤
KR20140015266A (ko) * 2010-11-24 2014-02-06 듀렉트 코퍼레이션 생분해성 약물 전달 조성물
EP2723800B1 (fr) 2011-06-23 2015-10-07 DSM IP Assets B.V. Microparticules ou nanoparticules comprenant un copolymère biodégradable de polyesteramide destinées à une utilisation dans l'administration d'agents bioactifs
US9873765B2 (en) 2011-06-23 2018-01-23 Dsm Ip Assets, B.V. Biodegradable polyesteramide copolymers for drug delivery
US20140294977A1 (en) * 2011-11-23 2014-10-02 Durect Corporation Radiation-Sterilized Biodegradable Drug Delivery Composition
US8822423B2 (en) 2012-05-17 2014-09-02 Janssen Biotech, Inc. Affinity peptides toward infliximab
GB201314452D0 (en) * 2013-08-13 2013-09-25 Ostara Biomedical Ltd Embryo implantation
WO2015064591A1 (fr) * 2013-10-28 2015-05-07 テルモ株式会社 Suspension aqueuse de protéine
JP6564369B2 (ja) 2013-12-09 2019-08-21 デュレクト コーポレイション 薬学的活性剤複合体、ポリマー複合体、ならびにこれらを伴う組成物及び方法
GB201409451D0 (en) 2014-05-28 2014-07-09 Ipabc Ltd Antimicrobial preparations, methods for preparing the same and uses thereof to combat microorganisms
US10434071B2 (en) 2014-12-18 2019-10-08 Dsm Ip Assets, B.V. Drug delivery system for delivery of acid sensitivity drugs
GB201501302D0 (en) 2015-01-27 2015-03-11 Ostara Biomedical Ltd Embryo implantation
GB201517523D0 (en) 2015-10-05 2015-11-18 Ostara Biomedical Ltd Methods and compositions for managing reproduction
TWI787230B (zh) 2017-01-20 2022-12-21 法商賽諾菲公司 抗TGF-β抗體及其用途
TWI788321B (zh) * 2017-01-20 2023-01-01 美商健臻公司 骨靶向抗體
JP7104929B2 (ja) * 2017-07-24 2022-07-22 テルモ株式会社 医療用タンパク質とポリアミノ酸とを含む複合体の製造方法および医療用タンパク質とポリアミノ酸とを含む複合体
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Also Published As

Publication number Publication date
CA2512001A1 (fr) 2004-07-22
EP1585771A4 (fr) 2006-11-29
JP2006523609A (ja) 2006-10-19
NZ571243A (en) 2010-04-30
BR0317896A (pt) 2005-12-06
JP2010174036A (ja) 2010-08-12
US20060008532A1 (en) 2006-01-12
MXPA05007182A (es) 2006-04-07
NZ554885A (en) 2009-07-31
CO5640146A2 (es) 2006-05-31
AU2003300126B2 (en) 2010-04-01
EP1585771A1 (fr) 2005-10-19
AU2003300126A1 (en) 2004-07-29
WO2004060920A1 (fr) 2004-07-22
KR20050094832A (ko) 2005-09-28

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