ZA200503534B - Implantation of encapsulated biological materials for treating diseases - Google Patents

Implantation of encapsulated biological materials for treating diseases Download PDF

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Publication number
ZA200503534B
ZA200503534B ZA200503534A ZA200503534A ZA200503534B ZA 200503534 B ZA200503534 B ZA 200503534B ZA 200503534 A ZA200503534 A ZA 200503534A ZA 200503534 A ZA200503534 A ZA 200503534A ZA 200503534 B ZA200503534 B ZA 200503534B
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ZA
South Africa
Prior art keywords
composition
cells
encapsulated
peg
cell
Prior art date
Application number
ZA200503534A
Other languages
English (en)
Inventor
David Scharp
Paul Latta
Chengyun Yue
Jeffrey Hubbell
Xiaojie Yu
Original Assignee
Novocell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novocell Inc filed Critical Novocell Inc
Publication of ZA200503534B publication Critical patent/ZA200503534B/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012—Cell encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0677—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/126—Immunoprotecting barriers, e.g. jackets, diffusion chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/74—Alginate
ZA200503534A 2002-10-11 2005-05-04 Implantation of encapsulated biological materials for treating diseases ZA200503534B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41901502P 2002-10-11 2002-10-11

Publications (1)

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ZA200503534B true ZA200503534B (en) 2006-08-30

Family

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Family Applications (1)

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ZA200503534A ZA200503534B (en) 2002-10-11 2005-05-04 Implantation of encapsulated biological materials for treating diseases

Country Status (14)

Country Link
US (2) US7427415B2 (ru)
EP (1) EP1553893A4 (ru)
JP (1) JP2006503080A (ru)
KR (1) KR20050055760A (ru)
CN (1) CN1703175A (ru)
AU (1) AU2003285887B2 (ru)
BR (1) BR0315130A (ru)
CA (1) CA2501949A1 (ru)
MX (1) MXPA05003829A (ru)
NZ (1) NZ539713A (ru)
PL (1) PL376471A1 (ru)
RU (1) RU2340330C2 (ru)
WO (1) WO2004032881A2 (ru)
ZA (1) ZA200503534B (ru)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1301626A4 (en) * 2000-05-08 2004-06-02 Qtl Biosystems Llc IMPROVEMENTS TO THE QTL-POLYMER FLUORESCENT BIODETECTION APPROACH
US7440806B1 (en) * 2000-11-21 2008-10-21 Boston Scientific Neuromodulation Corp. Systems and methods for treatment of diabetes by electrical brain stimulation and/or drug infusion
US7493171B1 (en) * 2000-11-21 2009-02-17 Boston Scientific Neuromodulation Corp. Treatment of pathologic craving and aversion syndromes and eating disorders by electrical brain stimulation and/or drug infusion
US7608114B2 (en) 2002-12-02 2009-10-27 Gi Dynamics, Inc. Bariatric sleeve
US7122058B2 (en) 2002-12-02 2006-10-17 Gi Dynamics, Inc. Anti-obesity devices
US7025791B2 (en) 2002-12-02 2006-04-11 Gi Dynamics, Inc. Bariatric sleeve
US7678068B2 (en) 2002-12-02 2010-03-16 Gi Dynamics, Inc. Atraumatic delivery devices
US7695446B2 (en) 2002-12-02 2010-04-13 Gi Dynamics, Inc. Methods of treatment using a bariatric sleeve
US7585499B2 (en) 2003-04-10 2009-09-08 Surmodics, Inc. Method for encapsulation of cellular material using a charged initiator polymer
US7820158B2 (en) * 2003-04-10 2010-10-26 Surmodics, Inc. Ligand-coupled initiator polymers and methods of use
US8202833B2 (en) * 2003-11-26 2012-06-19 Surmodics, Inc. Composition containing biocompatible polymerization accelerator and polymerizable material
US8057420B2 (en) 2003-12-09 2011-11-15 Gi Dynamics, Inc. Gastrointestinal implant with drawstring
WO2005060882A1 (en) 2003-12-09 2005-07-07 Gi Dynamics, Inc. Apparatus to be anchored within the gastrointestinal tract and anchoring method
US20050180957A1 (en) * 2004-01-16 2005-08-18 Scharp David W. Method of using fibrin-bound angiogenic factors to stimulate vascularization of transplant site of encapsulated cells
DE602005027570D1 (de) 2004-07-09 2011-06-01 Gi Dynamics Inc Vorrichtungen für die platzierung einer gastrotintestinalen hülse
EP1799145B1 (en) 2004-09-17 2016-12-21 GI Dynamics, Inc. Gastrointestinal anchor
US7851189B2 (en) 2005-03-07 2010-12-14 Boston Scientific Scimed, Inc. Microencapsulated compositions for endoluminal tissue engineering
US7976488B2 (en) 2005-06-08 2011-07-12 Gi Dynamics, Inc. Gastrointestinal anchor compliance
WO2007002664A2 (en) * 2005-06-22 2007-01-04 Massachusetts Institute Of Technology Propagation of undifferentiated embryonic stem cells in hyaluronic acid hydrogel
WO2007047539A2 (en) * 2005-10-14 2007-04-26 Medtronic, Inc. Localized delivery to the lymphatic system
US20070098695A1 (en) * 2005-10-31 2007-05-03 Deolden James Methods of islet separation during isolation
CN101340887B (zh) 2005-11-09 2014-01-29 科洛斯科技公司 使牙齿增白的组合物及方法
CA2634245C (en) * 2005-12-28 2013-12-10 Dentsply International Inc. Light-curable bone growth material for treating dental bone defects
BRPI0600473A (pt) * 2006-02-06 2007-10-23 Phb Ind Sa implante polimérico e seu processo de preparação
KR101505382B1 (ko) 2006-03-07 2015-03-23 지타 쉬로프 인간 배아 줄기 세포 및 그의 유도체를 포함하는 조성물, 그의 사용 방법 및 제조 방법
US20090311328A1 (en) * 2006-03-31 2009-12-17 Csir Bulking of Soft Tissue
EP2015698B1 (en) 2006-04-20 2017-11-15 Sonendo, Inc. Apparatus for treating root canals of teeth
CN101522133B (zh) 2006-08-08 2012-08-08 伊纳斯米特基金会 可植入的光学系统，其开发和应用的方法
US7980854B2 (en) 2006-08-24 2011-07-19 Medical Dental Advanced Technologies Group, L.L.C. Dental and medical treatments and procedures
US20100266989A1 (en) 2006-11-09 2010-10-21 Klox Technologies Inc. Teeth whitening compositions and methods
US8801647B2 (en) 2007-02-22 2014-08-12 Gi Dynamics, Inc. Use of a gastrointestinal sleeve to treat bariatric surgery fistulas and leaks
EA024725B1 (ru) 2008-11-07 2016-10-31 Клокс Текнолоджиз Инк. Композиция для окислительного фотоактивируемого омоложения кожи, содержащая гиалуроновую кислоту, глюкозамин или аллантоин
WO2010057039A2 (en) 2008-11-14 2010-05-20 Cythera, Inc. Encapsulation of pancreatic cells derived from human pluripotent stem cells
RU2011127144A (ru) * 2008-12-02 2013-01-10 Конинклейке Филипс Электроникс Н.В. Соосно инкапсулированные клеточные суспензии и микроткани
IL196820A0 (en) 2009-02-01 2009-11-18 Yissum Res Dev Co Devitalized, acellular scaffold matrices derived from micro-organs seeded with various cells
ES2849181T3 (es) 2009-04-22 2021-08-16 Viacyte Inc Composiciones celulares derivadas de células reprogramadas desdiferenciadas
US9109245B2 (en) 2009-04-22 2015-08-18 Viacyte, Inc. Cell compositions derived from dedifferentiated reprogrammed cells
US20100318371A1 (en) * 2009-06-11 2010-12-16 Halliburton Energy Services, Inc. Comprehensive hazard evaluation system and method for chemicals and products
LT2453922T (lt) 2009-07-17 2017-12-27 Klox Technologies Inc. Antibakterinė oralinė kompozicija
US8709400B2 (en) * 2009-07-27 2014-04-29 Washington University Inducement of organogenetic tolerance for pancreatic xenotransplant
WO2011025977A2 (en) 2009-08-28 2011-03-03 Craig Hasilo Methods and devices for cellular transplantation
US8858990B2 (en) * 2009-09-17 2014-10-14 The Ohio State University Capsule of thermogenic cells for treating a metabolic disease
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US9433557B2 (en) 2011-02-21 2016-09-06 Viacyte, Inc. Loading system for an encapsulation device
WO2012154627A2 (en) * 2011-05-06 2012-11-15 California Institute Of Technology Light delivery device and related compositions, methods and systems
US11116841B2 (en) 2012-04-20 2021-09-14 Klox Technologies Inc. Biophotonic compositions, kits and methods
US20130281913A1 (en) 2012-04-20 2013-10-24 Klox Technologies Inc. Biophotonic compositions and methods for providing biophotonic treatment
JP6231570B2 (ja) 2012-09-14 2017-11-15 ヴァレアント ファーマシューティカルズ インターナショナル インコーポレイテッドＶａｌｅａｎｔ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｔｅｒｎａｔｉｏｎａｌ， Ｉｎｃ． 歯のホワイトニングのための組成物および方法
US20140276354A1 (en) 2013-03-14 2014-09-18 Klox Technologies Inc. Biophotonic materials and uses thereof
US8859286B2 (en) 2013-03-14 2014-10-14 Viacyte, Inc. In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (PEC) and endocrine cells
US9950149B2 (en) 2013-04-24 2018-04-24 Nestec S.A. Biomolecular cell encapsulation device and methods of implantation
CN103305453A (zh) * 2013-05-23 2013-09-18 侯亚义 一种脐带间充质干细胞的微载体培养系统
EP3013277B1 (en) 2013-06-26 2023-07-19 Sonendo, Inc. Apparatus and methods for filling teeth and root canals
EP3016686A4 (en) 2013-07-03 2017-01-25 Klox Technologies Inc. Biophotonic compositions comprising a chromophore and a gelling agent for treating wounds
AU2015240385B2 (en) 2014-04-01 2019-02-28 Klox Technologies Inc. Tissue filler compositions and methods of use
US11051900B2 (en) 2014-04-16 2021-07-06 Viacyte, Inc. Tools and instruments for use with implantable encapsulation devices
US11229607B2 (en) * 2014-06-30 2022-01-25 President And Fellows Of Harvard College Hydrogel compositions comprising encapsulated cells and methods of use thereof
JP2017528572A (ja) * 2014-09-15 2017-09-28 クロックス テクノロジーズ インコーポレイテッドＫｌｏｘ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ． 放射性高分子マトリクス
ES2856841T3 (es) 2014-10-31 2021-09-28 Klox Tech Inc Fibras y medios de tela fotoactivables
CN104893825A (zh) * 2015-06-11 2015-09-09 东华大学 一种以聚脲为囊壁的香精微胶囊及其制备方法
US10918673B2 (en) 2015-08-28 2021-02-16 The Regents Of The University Of Michigan Immunoisolation device
US10576042B2 (en) 2015-11-23 2020-03-03 Association For The Advancement Of Tissue Engineering Cell Based Technologies & Therapies Associaçao Composition comprising polyelectrolyte complexes, methods and uses thereof
US20170252304A1 (en) * 2016-03-01 2017-09-07 Prodo Laboratories, Inc. Encapsulation Methods and Compositions
EP3426263A4 (en) * 2016-03-09 2019-10-16 Incube Labs, LLC METHOD AND ARTICLE FOR THE DELIVERY OF LIVABLE CELLS IN SOLID TISSUE
US11655343B2 (en) 2016-03-24 2023-05-23 Takeda Pharmaceutical Company Limited Alginate hydrogel compositions
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
US20180035924A1 (en) * 2016-08-02 2018-02-08 Medtronic, Inc. Accelerometer signal change as a measure of patient functional status
US11052230B2 (en) 2016-11-08 2021-07-06 W. L. Gore & Associates, Inc. Implantable encapsulation devices
RU2019114817A (ru) * 2016-11-15 2020-11-16 Джинер Лайф Сайенс, Инк. Устройство чрезкожной диффузии газов, подходящее для применения с подкожным имплантатом
EP3554569A1 (en) * 2016-12-13 2019-10-23 Millennium Pharmaceuticals, Inc. Conformal coating of biological surfaces
CN110709137A (zh) * 2017-04-06 2020-01-17 塞拉克西斯股份有限公司 大胶囊化的治疗性细胞及其使用方法
WO2019152767A1 (en) * 2018-02-02 2019-08-08 Wake Forest University Health Sciences Organoids related to immunotherapy and methods of preparing and using the same
CN113727742A (zh) * 2019-03-29 2021-11-30 南洋理工大学 治疗性水凝胶装置
WO2020223706A1 (en) * 2019-05-02 2020-11-05 Sonendo, Inc. Hydrogel materials for obturation
CN110251731B (zh) * 2019-06-26 2021-09-03 山东百多安医疗器械股份有限公司 一种组织工程用胰岛细胞微囊及其制备方法
CN110201234B (zh) * 2019-06-26 2021-09-03 山东百多安医疗器械股份有限公司 一种组织工程用前列腺细胞微囊及其制备方法
FR3108260B1 (fr) * 2020-03-17 2024-01-05 Neurobiomat Hydrogel hétérogène hybride, procédé de fabrication et utilisation comme implant de comblement non-dégradable in-situ
USD997355S1 (en) 2020-10-07 2023-08-29 Sonendo, Inc. Dental treatment instrument
US20240041755A1 (en) * 2020-12-22 2024-02-08 William Marsh Rice University Implantable constructs for modulating an immune response
CN114949369B (zh) * 2021-02-19 2023-09-05 清华大学 一种人工组织器官的封装装置及其制备方法和应用
WO2023164171A2 (en) 2022-02-25 2023-08-31 Viacyte, Inc. Multilayer implantable cell encapsulation devices and methods thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5168053A (en) 1989-03-24 1992-12-01 Yale University Cleavage of targeted RNA by RNAase P
US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5380536A (en) 1990-10-15 1995-01-10 The Board Of Regents, The University Of Texas System Biocompatible microcapsules
US5232984A (en) 1990-10-15 1993-08-03 The Board Of The Regents The University Of Texas Biocompatible microcapsules
US20030087985A1 (en) 1990-10-15 2003-05-08 Hubbell Jeffrey A. Gels for encapsulation of biological materials
US5462990A (en) 1990-10-15 1995-10-31 Board Of Regents, The University Of Texas System Multifunctional organic polymers
US5529914A (en) 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
US5626863A (en) 1992-02-28 1997-05-06 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
AU3124793A (en) 1991-10-29 1993-06-07 Clover Consolidated, Limited Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release
US5545423A (en) 1991-11-25 1996-08-13 Vivorx, Inc. Cytoprotective, biocompatible, retrievable macrocapsule containment systems for biologically active materials
US5573934A (en) 1992-04-20 1996-11-12 Board Of Regents, The University Of Texas System Gels for encapsulation of biological materials
ATE197125T1 (de) 1992-02-28 2000-11-15 Univ Texas Photopolymerinierbare, biologisch abbaubare hydrogele als gewebekontaktmaterialien und trägerstoffe für kontrollierte freisetzung
US5578442A (en) * 1992-03-23 1996-11-26 Vivorx, Inc. Graft copolymers of polycationic species and water-soluble polymers, and use therefor
US5334640A (en) 1992-04-08 1994-08-02 Clover Consolidated, Ltd. Ionically covalently crosslinked and crosslinkable biocompatible encapsulation compositions and methods
WO1996029370A2 (en) 1995-03-23 1996-09-26 Focal, Inc. Redox and photoinitiator systems for priming for improved adherence of gels to substrates
US6565842B1 (en) 1995-06-07 2003-05-20 American Bioscience, Inc. Crosslinkable polypeptide compositions
US5714360A (en) 1995-11-03 1998-02-03 Bsi Corporation Photoactivatable water soluble cross-linking agents containing an onium group
JP4803853B2 (ja) 1996-09-23 2011-10-26 ジェンザイム・コーポレーション カーボネートまたはジオキサノン結合を含む重合可能な生体分解性のポリマー
US6368612B1 (en) * 1997-12-12 2002-04-09 Biohybrid Technologies Llc Devices for cloaking transplanted cells
US6410044B1 (en) 1998-03-19 2002-06-25 Surmodics, Inc. Crosslinkable macromers
US6007833A (en) 1998-03-19 1999-12-28 Surmodics, Inc. Crosslinkable macromers bearing initiator groups
US6326201B1 (en) 1999-02-10 2001-12-04 Curis, Inc. Pancreatic progenitor cells, methods and uses related thereto
US6495161B1 (en) 1999-03-09 2002-12-17 Vivorx, Inc. Cytoprotective biocompatible containment systems for biologically active materials and methods of making same
US6278018B1 (en) 1999-12-14 2001-08-21 Surmodics, Inc. Surface coating agents
FR2814752A1 (fr) 2000-10-02 2002-04-05 Chru Lille Procede d'obtention in vitro de cellules insulino- secretrices de mammifere et leurs utilisations

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AU2003285887B2 (en) 2008-09-11
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