ZA200502375B - Imidazopyrazines as cyclin dependent kinase inhibitors. - Google Patents

Imidazopyrazines as cyclin dependent kinase inhibitors. Download PDF

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Publication number
ZA200502375B
ZA200502375B ZA200502375A ZA200502375A ZA200502375B ZA 200502375 B ZA200502375 B ZA 200502375B ZA 200502375 A ZA200502375 A ZA 200502375A ZA 200502375 A ZA200502375 A ZA 200502375A ZA 200502375 B ZA200502375 B ZA 200502375B
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mmol
mixture
lcms
stirred
nas
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ZA200502375A
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Inventor
Kamil Paruch
Michael P Dwyer
Viyyoor M Girijavallabhan
Timothy J Guzi
Ronald J Doll
Alan K Mallams
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Schering Corp
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Publication of ZA200502375B publication Critical patent/ZA200502375B/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200502375A 2002-09-23 2005-03-22 Imidazopyrazines as cyclin dependent kinase inhibitors. ZA200502375B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41299702P 2002-09-23 2002-09-23

Publications (1)

Publication Number Publication Date
ZA200502375B true ZA200502375B (en) 2005-09-27

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Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200502375A ZA200502375B (en) 2002-09-23 2005-03-22 Imidazopyrazines as cyclin dependent kinase inhibitors.

Country Status (19)

Country Link
US (2) US6919341B2 (de)
EP (1) EP1543008B1 (de)
JP (1) JP4799864B2 (de)
KR (1) KR20050057520A (de)
CN (1) CN1694886A (de)
AR (1) AR041347A1 (de)
AT (1) ATE377600T1 (de)
AU (1) AU2003272476B2 (de)
CA (1) CA2499756C (de)
DE (1) DE60317353T2 (de)
ES (1) ES2293015T3 (de)
HK (1) HK1072056A1 (de)
MX (1) MXPA05003120A (de)
MY (1) MY134589A (de)
NZ (2) NZ563374A (de)
PE (1) PE20050081A1 (de)
TW (1) TW200413378A (de)
WO (1) WO2004026877A1 (de)
ZA (1) ZA200502375B (de)

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Also Published As

Publication number Publication date
EP1543008A1 (de) 2005-06-22
CA2499756C (en) 2011-07-12
DE60317353D1 (de) 2007-12-20
AU2003272476B2 (en) 2007-07-05
ATE377600T1 (de) 2007-11-15
WO2004026877A1 (en) 2004-04-01
PE20050081A1 (es) 2005-03-01
MY134589A (en) 2007-12-31
JP2006507253A (ja) 2006-03-02
US20050130980A1 (en) 2005-06-16
NZ538685A (en) 2008-02-29
CA2499756A1 (en) 2004-04-01
MXPA05003120A (es) 2005-06-22
NZ563374A (en) 2009-06-26
AR041347A1 (es) 2005-05-11
DE60317353T2 (de) 2008-08-28
CN1694886A (zh) 2005-11-09
HK1072056A1 (en) 2005-08-12
AU2003272476A1 (en) 2004-04-08
ES2293015T3 (es) 2008-03-16
KR20050057520A (ko) 2005-06-16
TW200413378A (en) 2004-08-01
EP1543008B1 (de) 2007-11-07
US6919341B2 (en) 2005-07-19
US20040063715A1 (en) 2004-04-01
JP4799864B2 (ja) 2011-10-26
US7432265B2 (en) 2008-10-07

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