ZA200501102B - Bio-chip prepared by gelation on a chip substrate - Google Patents

Bio-chip prepared by gelation on a chip substrate Download PDF

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Publication number
ZA200501102B
ZA200501102B ZA200501102A ZA200501102A ZA200501102B ZA 200501102 B ZA200501102 B ZA 200501102B ZA 200501102 A ZA200501102 A ZA 200501102A ZA 200501102 A ZA200501102 A ZA 200501102A ZA 200501102 B ZA200501102 B ZA 200501102B
Authority
ZA
South Africa
Prior art keywords
chip
sol
biochip
range
chip substrate
Prior art date
Application number
ZA200501102A
Other languages
English (en)
Inventor
Kim So Youn
Kim Kyun Young
Ha Jeong Min
Park Hye Sang
Jang Jae Young
Kim Young Duk
Kim Phil Seok
Original Assignee
Lg Chemical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Chemical Ltd filed Critical Lg Chemical Ltd
Publication of ZA200501102B publication Critical patent/ZA200501102B/en

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00351Means for dispensing and evacuation of reagents
    • B01J2219/00378Piezoelectric or ink jet dispensers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/00527Sheets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/00527Sheets
    • B01J2219/00533Sheets essentially rectangular
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00572Chemical means
    • B01J2219/00576Chemical means fluorophore
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00572Chemical means
    • B01J2219/00581Mass
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00585Parallel processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00596Solid-phase processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00639Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
    • B01J2219/00644Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium the porous medium being present in discrete locations, e.g. gel pads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00659Two-dimensional arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00677Ex-situ synthesis followed by deposition on the substrate
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068Means for controlling the apparatus of the process
    • B01J2219/00693Means for quality control
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00722Nucleotides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00725Peptides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00729Peptide nucleic acids [PNA]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/0074Biological products
    • B01J2219/00743Cells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
ZA200501102A 2002-09-13 2005-02-07 Bio-chip prepared by gelation on a chip substrate ZA200501102B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR20020055635 2002-09-13

Publications (1)

Publication Number Publication Date
ZA200501102B true ZA200501102B (en) 2007-02-28

Family

ID=36574752

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200501102A ZA200501102B (en) 2002-09-13 2005-02-07 Bio-chip prepared by gelation on a chip substrate

Country Status (8)

Country Link
US (1) US20060121474A1 (zh)
EP (1) EP1546406A4 (zh)
JP (1) JP4307380B2 (zh)
KR (2) KR100601831B1 (zh)
CN (1) CN100412203C (zh)
AU (1) AU2003260979A1 (zh)
WO (1) WO2004024955A1 (zh)
ZA (1) ZA200501102B (zh)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100334229C (zh) * 2005-06-17 2007-08-29 东南大学 基于凝胶固定核酸的dna微阵列芯片制备方法
WO2007037069A1 (ja) * 2005-09-27 2007-04-05 Sumitomo Bakelite Company, Ltd. 医療用粒子及びその製造方法
KR100784437B1 (ko) 2006-01-27 2007-12-11 김소연 표면처리 되지 않은 기질에 표지물질을 고정하기 위한졸-겔 바이오칩용 졸 조성물 및 그의 스크리닝 방법
RU2309959C1 (ru) * 2006-02-22 2007-11-10 Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук Применение немодифицированных полимерных материалов для изготовления подложки биочипов, биочип на их основе и способ его изготовления, способ иммобилизации гидрогелей на немодифицированных полимерных материалах
KR100718918B1 (ko) 2006-02-27 2007-05-17 충주대학교 산학협력단 나노기공성 하이드로겔 고분자 팁, 그 제조방법 및 이를이용한 생체물질의 패터닝 방법
US20080261199A1 (en) * 2006-04-26 2008-10-23 Genscript Corporation Rapid detection processes and related compositions
US8158411B2 (en) 2006-08-21 2012-04-17 Samsung Electronics Co., Ltd. Method of separating microorganism using nonplanar solid substrate and device for separating microorganism using the same
DE102007005462A1 (de) * 2007-01-30 2008-07-31 Universität Zu Köln Verfahren zur Herstellung von biokompatiblen Hybrimeren
KR100866524B1 (ko) 2007-05-23 2008-11-03 전남대학교산학협력단 형광염료 및 효소의 고정화를 위한 졸-겔 조성물, 및 이를이용한 검출키트 및 방법
US8828912B2 (en) 2009-09-21 2014-09-09 Akonni Biosystems, Inc. Method of making a microarray assembly
KR101368178B1 (ko) * 2008-01-07 2014-02-26 삼성전자주식회사 미세유동장치 내의 유체 흐름 경로에 필터를 형성하는 방법
US20090291214A1 (en) * 2008-05-23 2009-11-26 Battelle Memorial Institute Protein inks of colloidal immobilized proteins
EP2305789A4 (en) * 2008-06-27 2013-12-25 Hitachi Plant Technologies Ltd CASSETTE FOR MICROBEN CELLS, CARRIER, CARRIER TREATMENT DEVICE AND METHOD FOR COUNTING MICROBIAL CELLS
KR100984735B1 (ko) * 2009-05-28 2010-10-01 동국대학교 산학협력단 신개념 신약개발을 위한 타겟 단백질­단백질 상호작용을 저해하는 신약후보물질의 스크리닝 방법
KR101218982B1 (ko) * 2010-05-03 2013-01-04 삼성전기주식회사 세포 칩, 이의 제조방법 및 세포 칩 제조장치
CN102140553B (zh) * 2011-03-30 2012-12-26 中华人民共和国北京出入境检验检疫局 基于全基因组探针的hiv亚型检测基因芯片
KR101274765B1 (ko) * 2011-04-27 2013-06-14 피씨엘 (주) 바이오칩 제조용 졸-겔 키트 및 이를 이용한 바이오 칩의 제조방법
WO2012148017A1 (ko) * 2011-04-27 2012-11-01 피씨엘(주) 바이오칩 제조용 졸-겔 키트 및 이를 이용한 바이오 칩의 제조방법
WO2013096528A1 (en) 2011-12-20 2013-06-27 Siemens Healthcare Diagnostics Inc. Coated substrates for high energy capture phase binding and methods of production and use thereof
KR101569891B1 (ko) * 2012-02-13 2015-11-27 동국대학교 산학협력단 다공성 지지체를 이용한 저분자 포집용 졸-겔 칩 및 이를 이용한 저분자 특이적 물질의 스크리닝 방법
WO2013165133A1 (ko) * 2012-04-30 2013-11-07 피씨엘(주) 졸겔 칩 제작을 위한 개선된 졸 조성물 분주용 노즐 및 이를 함유하는 졸겔 칩 제조용 장치
WO2017146508A1 (ko) * 2016-02-23 2017-08-31 노을 주식회사 진단 방법 및 이를 수행하는 기기
KR20170099737A (ko) 2016-02-23 2017-09-01 노을 주식회사 접촉식 염색 패치 및 이를 이용하는 염색 방법
WO2017146506A1 (ko) * 2016-02-23 2017-08-31 노을 주식회사 혈액 염색 패치, 이를 이용하는 혈액 검사 방법 및 장치
WO2017146507A1 (ko) * 2016-02-23 2017-08-31 노을 주식회사 배양 패치, 배양 방법, 배양 검사 방법, 배양 검사 장치, 약물 검사 방법 및 약물 검사 장치
US10371610B2 (en) 2016-02-23 2019-08-06 Noul Co., Ltd. Contact-type patch, staining method using the same, and manufacturing method thereof
WO2017146505A1 (ko) * 2016-02-23 2017-08-31 노을 주식회사 물질 표지 패치, 이를 이용하는 조직 진단 방법 및 장치
US20210164871A1 (en) * 2018-05-03 2021-06-03 Noul Co., Ltd. Specimen inspecting method
GB2594813A (en) * 2019-01-09 2021-11-10 Hitachi High Tech Corp Substrate for nucleic acid analysis, flow cell for nucleic acid analysis, and image analysis method

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0162017B1 (de) * 1984-05-17 1991-08-21 Ciba-Geigy Ag Homo- und Copolymere, Verfahren zu deren Vernetzung und derenVerwendung
US5108891A (en) * 1988-06-09 1992-04-28 Beth Israel Medical Center Aids assay
IL93134A (en) * 1990-01-23 1997-11-20 Yissum Res Dev Co Doped sol-gel glasses for obtaining chemical interactions
DE4409786A1 (de) * 1994-03-22 1995-09-28 Boehringer Mannheim Gmbh Objektträger zur mikroskopischen Auswertung flüssiger Proben
US5624743A (en) * 1996-02-26 1997-04-29 Xerox Corporation Ink jet transparencies
US5725788A (en) * 1996-03-04 1998-03-10 Motorola Apparatus and method for patterning a surface
US6087102A (en) * 1998-01-07 2000-07-11 Clontech Laboratories, Inc. Polymeric arrays and methods for their use in binding assays
DE10011400A1 (de) * 1999-03-11 2000-10-05 Nigu Chemie Gmbh Verfahren zur gezielten photolytischen Abspaltung der bei der DNA-Chip-Herstellung üblichen Schutzgruppen von Nucleosid-Derivaten
US6174683B1 (en) * 1999-04-26 2001-01-16 Biocept, Inc. Method of making biochips and the biochips resulting therefrom
US20020015952A1 (en) * 1999-07-30 2002-02-07 Anderson Norman G. Microarrays and their manufacture by slicing
US7678539B2 (en) * 2000-08-10 2010-03-16 Corning Incorporated Arrays of biological membranes and methods and use thereof
TW523548B (en) * 2000-09-04 2003-03-11 Ind Tech Res Inst High-density functional slide and preparation method thereof
KR20020089315A (ko) * 2000-10-26 2002-11-29 바이오셉트 인코포레이티드 3차원 포맷 바이오칩
US20020123134A1 (en) * 2000-12-26 2002-09-05 Mingxian Huang Active and biocompatible platforms prepared by polymerization of surface coating films
US7427497B2 (en) * 2001-11-01 2008-09-23 Rensselaer Polytechnic Institute In vitro metabolic engineering on microscale devices

Also Published As

Publication number Publication date
KR20040024510A (ko) 2004-03-20
KR20060061324A (ko) 2006-06-07
CN1681943A (zh) 2005-10-12
JP4307380B2 (ja) 2009-08-05
WO2004024955A1 (en) 2004-03-25
EP1546406A4 (en) 2005-11-23
US20060121474A1 (en) 2006-06-08
AU2003260979A1 (en) 2004-04-30
KR100663031B1 (ko) 2006-12-28
EP1546406A1 (en) 2005-06-29
CN100412203C (zh) 2008-08-20
KR100601831B1 (ko) 2006-07-14
JP2005539215A (ja) 2005-12-22

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