ZA200500214B - Method for mapping and eliminating T-cell epitopes. - Google Patents

Method for mapping and eliminating T-cell epitopes.

Info

Publication number
ZA200500214B
ZA200500214B ZA200500214A ZA200500214A ZA200500214B ZA 200500214 B ZA200500214 B ZA 200500214B ZA 200500214 A ZA200500214 A ZA 200500214A ZA 200500214 A ZA200500214 A ZA 200500214A ZA 200500214 B ZA200500214 B ZA 200500214B
Authority
ZA
South Africa
Prior art keywords
epitopes
identification
mapping
eliminating
cell epitopes
Prior art date
Application number
ZA200500214A
Other languages
English (en)
Inventor
Matthew Baker
Graham Carter
Francis J Carr
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29724386&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200500214(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA200500214B publication Critical patent/ZA200500214B/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA200500214A 2002-06-11 2005-01-10 Method for mapping and eliminating T-cell epitopes. ZA200500214B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02012919 2002-06-11

Publications (1)

Publication Number Publication Date
ZA200500214B true ZA200500214B (en) 2006-02-22

Family

ID=29724386

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200500214A ZA200500214B (en) 2002-06-11 2005-01-10 Method for mapping and eliminating T-cell epitopes.

Country Status (16)

Country Link
EP (1) EP1512004B1 (de)
JP (1) JP2005529170A (de)
CN (1) CN100401064C (de)
AT (1) ATE320603T1 (de)
AU (1) AU2003273679A1 (de)
BR (1) BR0311720A (de)
CA (1) CA2489180A1 (de)
DE (1) DE60304040T2 (de)
DK (1) DK1512004T3 (de)
ES (1) ES2257680T3 (de)
MX (1) MXPA04012209A (de)
PL (1) PL371675A1 (de)
PT (1) PT1512004E (de)
RU (1) RU2334235C2 (de)
WO (1) WO2003104803A2 (de)
ZA (1) ZA200500214B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004074486A2 (en) * 2003-02-18 2004-09-02 Merck Patent Gmbh Fusion proteins of interferon alpha muteins with improved properties
PT1737961E (pt) 2004-03-19 2013-08-26 Merck Patent Gmbh Proteínas buganina modificadas, citotoxinas e métodos e utilizações das mesmas
FR2940451B1 (fr) 2008-12-18 2014-09-12 Proteus Procede d'evaluation de l'immunogenicite des proteines

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001349A (en) * 1995-02-22 1999-12-14 Therion Biologics Corporation Generation of human cytotoxic T-cells specific for carcinoma self-associated antigens and uses thereof
US5945401A (en) * 1995-06-23 1999-08-31 Conlon; Paul J. Peptide analogues of the 65KD isoform of human glutamic acid decarboxylase and uses thereof
US6165460A (en) * 1995-07-10 2000-12-26 Therion Biologics Corporation Generation of immune responses to prostate-specific antigen (PSA)
ATE412175T1 (de) * 1996-03-21 2008-11-15 Circassia Ltd Verwendung von kryptischen peptiden zur induktion von immunologischer toleranz
US5750356A (en) * 1996-05-31 1998-05-12 Anergen, Inc. Method for monitoring T cell reactivity
EP0983303B1 (de) * 1997-05-21 2006-03-08 Biovation Limited Verfahren zur herstellung von nicht-immunogenen proteinen
WO2000034317A2 (en) * 1998-12-08 2000-06-15 Biovation Limited Method for reducing immunogenicity of proteins
WO2002040997A2 (en) * 2000-10-02 2002-05-23 Genencor International, Inc. Production and use of proteins producing an altered immunogenic response

Also Published As

Publication number Publication date
JP2005529170A (ja) 2005-09-29
WO2003104803A3 (en) 2004-04-15
CA2489180A1 (en) 2003-12-18
ATE320603T1 (de) 2006-04-15
ES2257680T3 (es) 2006-08-01
WO2003104803A2 (en) 2003-12-18
RU2005100758A (ru) 2006-01-20
EP1512004B1 (de) 2006-03-15
DK1512004T3 (da) 2006-06-06
MXPA04012209A (es) 2005-02-25
EP1512004A2 (de) 2005-03-09
RU2334235C2 (ru) 2008-09-20
CN1659437A (zh) 2005-08-24
AU2003273679A1 (en) 2003-12-22
PT1512004E (pt) 2006-08-31
BR0311720A (pt) 2005-03-01
DE60304040T2 (de) 2006-09-28
PL371675A1 (en) 2005-06-27
CN100401064C (zh) 2008-07-09
DE60304040D1 (de) 2006-05-11

Similar Documents

Publication Publication Date Title
ATE475675T1 (de) Verwendung prokariotischer pest-ähnlicher peptide zur verstärkung der immunogenität von antigenen
DK1553975T3 (da) Optimerede Fc-varianter og fremgangsmåder til generering heraf.
IL172854A0 (en) Autologous self-tolerance inducing cells of monocytic origin and their use in pharmaceutical preparations
PT1512014E (pt) Método de identificação de alo-antigénios e sua utilização para terapia de cancro e transplante
NO20060843L (no) RG1-antistoffer og anvendelser derav
WO2004091543A3 (en) Method of treating autoimmune disease by inducing antigen presentation by tolerance inducing antigen presenting cells
WO2005018424A3 (en) Antibodies specific for fibrillar amyloid and a procedure to detect fibrillar amyloid deposits
NO20054351L (no) Monoklonalt antistoff og hybridom som produserer dette
BRPI0513135A (pt) bibliotecas de polinucleotìdeos, método de produção das mesmas, método de identificação de um polinucleotìdeo, região de ligação, meio adequado para uso em um, dispositivo eletrÈnico e dispositivo
DK1328547T3 (da) Identifikation og modifikation af immundominante epitoper i polypeptider
WO2004007547A3 (en) Truncated tau proteins
DK1620456T3 (da) Hla-a2 tumor-associerede antigen-peptider og præparater
WO2003068941A3 (en) Modulation of immune response by non-peptide binding stress response polypeptides
IL163902A0 (en) Antibodies against cancer antigen tmeff2 and uses thereof
CY1117746T1 (el) Αντιγονα αιμοφιλου της γριπης και αντιστοιχα θραυσματα dna
EP1090294A4 (de) Verfahren um die anwesenheit von krebs in einer probe zu bestimmen durch nachweis der expression eines ssx-gens und peptiden, die von ssx oder ny-eso-1 abgeleitet sind
MXPA02007665A (es) Trazado de despliegue diferencial de proteinas.
WO2004035742A3 (en) Sets of digital antibodies directed against short epitopes, and methods using same
DE60315827D1 (de) Verbesserte polysaccharid- und glykokonjugat-vakzine
ZA200500214B (en) Method for mapping and eliminating T-cell epitopes.
ATE316577T1 (de) Das goodpasture-antigen bindende protein
MY144766A (en) Plant virus coat fusion proteins with gdf8 epitopes and vaccines thereof
NO20005952D0 (no) Neisseria Meningitidis antigene polypeptider, korresponderende polynukleotider og beskyttende antistoffer
MXPA04000648A (es) Identificacion de antigenos especificos del tumor por medio de seleccion de bibliotecas de acido desoxirribonucleico complementario con sueros y uso de antigenos en tecnicas de formacion de imagenes de diagnostico.
EP1575479A4 (de) Hsp-peptide und analoga zur modulation von immunantworten über antigen präsentierende zellen