DK1512004T3 - Fremgangsmåde til kortlægning og eliminering af T-celleepitoper - Google Patents

Fremgangsmåde til kortlægning og eliminering af T-celleepitoper

Info

Publication number
DK1512004T3
DK1512004T3 DK03740219T DK03740219T DK1512004T3 DK 1512004 T3 DK1512004 T3 DK 1512004T3 DK 03740219 T DK03740219 T DK 03740219T DK 03740219 T DK03740219 T DK 03740219T DK 1512004 T3 DK1512004 T3 DK 1512004T3
Authority
DK
Denmark
Prior art keywords
epitopes
identification
mapping
eliminating
cell epitopes
Prior art date
Application number
DK03740219T
Other languages
English (en)
Inventor
Matthew Baker
Francis J Carr
Graham Carter
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29724386&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1512004(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Application granted granted Critical
Publication of DK1512004T3 publication Critical patent/DK1512004T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK03740219T 2002-06-11 2003-06-11 Fremgangsmåde til kortlægning og eliminering af T-celleepitoper DK1512004T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02012919 2002-06-11

Publications (1)

Publication Number Publication Date
DK1512004T3 true DK1512004T3 (da) 2006-06-06

Family

ID=29724386

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03740219T DK1512004T3 (da) 2002-06-11 2003-06-11 Fremgangsmåde til kortlægning og eliminering af T-celleepitoper

Country Status (16)

Country Link
EP (1) EP1512004B1 (da)
JP (1) JP2005529170A (da)
CN (1) CN100401064C (da)
AT (1) ATE320603T1 (da)
AU (1) AU2003273679A1 (da)
BR (1) BR0311720A (da)
CA (1) CA2489180A1 (da)
DE (1) DE60304040T2 (da)
DK (1) DK1512004T3 (da)
ES (1) ES2257680T3 (da)
MX (1) MXPA04012209A (da)
PL (1) PL371675A1 (da)
PT (1) PT1512004E (da)
RU (1) RU2334235C2 (da)
WO (1) WO2003104803A2 (da)
ZA (1) ZA200500214B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004213565A1 (en) * 2003-02-18 2004-09-02 Merck Patent Gmbh Fusion proteins of interferon alpha muteins with improved properties
EA010803B1 (ru) * 2004-03-19 2008-12-30 Мерк Патент Гмбх Модифицированные белки буганины, цитотоксины и способы их применения
FR2940451B1 (fr) 2008-12-18 2014-09-12 Proteus Procede d'evaluation de l'immunogenicite des proteines

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001349A (en) * 1995-02-22 1999-12-14 Therion Biologics Corporation Generation of human cytotoxic T-cells specific for carcinoma self-associated antigens and uses thereof
US5945401A (en) * 1995-06-23 1999-08-31 Conlon; Paul J. Peptide analogues of the 65KD isoform of human glutamic acid decarboxylase and uses thereof
US6165460A (en) * 1995-07-10 2000-12-26 Therion Biologics Corporation Generation of immune responses to prostate-specific antigen (PSA)
US6737406B1 (en) * 1996-03-21 2004-05-18 Circassia, Ltd. Cryptic peptides and method for their identification
US5750356A (en) * 1996-05-31 1998-05-12 Anergen, Inc. Method for monitoring T cell reactivity
EP1724282B1 (en) * 1997-05-21 2013-05-15 Merck Patent GmbH Method for the production of non-immunogenic proteins
EP1051432B1 (en) * 1998-12-08 2007-01-24 Biovation Limited Method for reducing immunogenicity of proteins
ATE504205T1 (de) * 2000-10-02 2011-04-15 Danisco Us Inc Methode zur bestimmung der immunogenität von proteinen, die eine veränderte immunantwort hervorrufen

Also Published As

Publication number Publication date
EP1512004A2 (en) 2005-03-09
EP1512004B1 (en) 2006-03-15
PL371675A1 (en) 2005-06-27
RU2334235C2 (ru) 2008-09-20
AU2003273679A1 (en) 2003-12-22
WO2003104803A2 (en) 2003-12-18
PT1512004E (pt) 2006-08-31
ATE320603T1 (de) 2006-04-15
WO2003104803A3 (en) 2004-04-15
CN100401064C (zh) 2008-07-09
RU2005100758A (ru) 2006-01-20
MXPA04012209A (es) 2005-02-25
DE60304040D1 (de) 2006-05-11
BR0311720A (pt) 2005-03-01
JP2005529170A (ja) 2005-09-29
CN1659437A (zh) 2005-08-24
ZA200500214B (en) 2006-02-22
DE60304040T2 (de) 2006-09-28
CA2489180A1 (en) 2003-12-18
ES2257680T3 (es) 2006-08-01

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