ATE320603T1 - Methode zur identifizierung und eliminierung von t-zell epitopen - Google Patents
Methode zur identifizierung und eliminierung von t-zell epitopenInfo
- Publication number
- ATE320603T1 ATE320603T1 AT03740219T AT03740219T ATE320603T1 AT E320603 T1 ATE320603 T1 AT E320603T1 AT 03740219 T AT03740219 T AT 03740219T AT 03740219 T AT03740219 T AT 03740219T AT E320603 T1 ATE320603 T1 AT E320603T1
- Authority
- AT
- Austria
- Prior art keywords
- identification
- epitopes
- elimination
- cell epitopes
- ligands
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000008030 elimination Effects 0.000 title 1
- 238000003379 elimination reaction Methods 0.000 title 1
- 239000003446 ligand Substances 0.000 abstract 2
- 238000013507 mapping Methods 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000043131 MHC class II family Human genes 0.000 abstract 1
- 108091054438 MHC class II family Proteins 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 238000013459 approach Methods 0.000 abstract 1
- 238000013461 design Methods 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in epitope analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02012919 | 2002-06-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE320603T1 true ATE320603T1 (de) | 2006-04-15 |
Family
ID=29724386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03740219T ATE320603T1 (de) | 2002-06-11 | 2003-06-11 | Methode zur identifizierung und eliminierung von t-zell epitopen |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1512004B1 (de) |
| JP (1) | JP2005529170A (de) |
| CN (1) | CN100401064C (de) |
| AT (1) | ATE320603T1 (de) |
| AU (1) | AU2003273679A1 (de) |
| BR (1) | BR0311720A (de) |
| CA (1) | CA2489180A1 (de) |
| DE (1) | DE60304040T2 (de) |
| DK (1) | DK1512004T3 (de) |
| ES (1) | ES2257680T3 (de) |
| MX (1) | MXPA04012209A (de) |
| PL (1) | PL371675A1 (de) |
| PT (1) | PT1512004E (de) |
| RU (1) | RU2334235C2 (de) |
| WO (1) | WO2003104803A2 (de) |
| ZA (1) | ZA200500214B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1594965A2 (de) * | 2003-02-18 | 2005-11-16 | MERCK PATENT GmbH | Fusionsproteine von interferon alpha muteinen mit verbesserten eigenschaften |
| PL1737961T3 (pl) * | 2004-03-19 | 2013-12-31 | Merck Patent Gmbh | Zmodyfikowane białka bouganiny, cytotoksyny i sposoby oraz ich zastosowania |
| FR2940451B1 (fr) | 2008-12-18 | 2014-09-12 | Proteus | Procede d'evaluation de l'immunogenicite des proteines |
| GB201917630D0 (en) * | 2019-12-03 | 2020-01-15 | Ge Healthcare Bio Sciences Ab | Method for determination of aggregates |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6001349A (en) * | 1995-02-22 | 1999-12-14 | Therion Biologics Corporation | Generation of human cytotoxic T-cells specific for carcinoma self-associated antigens and uses thereof |
| US5945401A (en) * | 1995-06-23 | 1999-08-31 | Conlon; Paul J. | Peptide analogues of the 65KD isoform of human glutamic acid decarboxylase and uses thereof |
| US6165460A (en) * | 1995-07-10 | 2000-12-26 | Therion Biologics Corporation | Generation of immune responses to prostate-specific antigen (PSA) |
| DE69733343D1 (de) * | 1996-03-21 | 2005-06-30 | Circassia Ltd | Kryptische peptide und verfahren zu ihrer identifizierung |
| US5750356A (en) * | 1996-05-31 | 1998-05-12 | Anergen, Inc. | Method for monitoring T cell reactivity |
| WO1998052976A1 (en) * | 1997-05-21 | 1998-11-26 | Biovation Limited | Method for the production of non-immunogenic proteins |
| EP1051432B1 (de) * | 1998-12-08 | 2007-01-24 | Biovation Limited | Verfahren zur verminderung der immunogenität von proteinen |
| CA2424720C (en) * | 2000-10-02 | 2012-04-03 | Genencor International, Inc. | Proteins producing an altered immunogenic response and methods of making and using the same |
-
2003
- 2003-06-11 EP EP03740219A patent/EP1512004B1/de not_active Revoked
- 2003-06-11 DE DE60304040T patent/DE60304040T2/de not_active Revoked
- 2003-06-11 DK DK03740219T patent/DK1512004T3/da active
- 2003-06-11 PT PT03740219T patent/PT1512004E/pt unknown
- 2003-06-11 BR BR0311720-0A patent/BR0311720A/pt not_active Application Discontinuation
- 2003-06-11 CA CA002489180A patent/CA2489180A1/en not_active Abandoned
- 2003-06-11 AU AU2003273679A patent/AU2003273679A1/en not_active Abandoned
- 2003-06-11 JP JP2004511824A patent/JP2005529170A/ja active Pending
- 2003-06-11 MX MXPA04012209A patent/MXPA04012209A/es unknown
- 2003-06-11 AT AT03740219T patent/ATE320603T1/de not_active IP Right Cessation
- 2003-06-11 RU RU2005100758/15A patent/RU2334235C2/ru not_active IP Right Cessation
- 2003-06-11 WO PCT/EP2003/006110 patent/WO2003104803A2/en not_active Ceased
- 2003-06-11 PL PL03371675A patent/PL371675A1/xx unknown
- 2003-06-11 ES ES03740219T patent/ES2257680T3/es not_active Expired - Lifetime
- 2003-06-11 CN CNB038134519A patent/CN100401064C/zh not_active Expired - Fee Related
-
2005
- 2005-01-10 ZA ZA200500214A patent/ZA200500214B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT1512004E (pt) | 2006-08-31 |
| CN1659437A (zh) | 2005-08-24 |
| RU2334235C2 (ru) | 2008-09-20 |
| DK1512004T3 (da) | 2006-06-06 |
| WO2003104803A2 (en) | 2003-12-18 |
| CA2489180A1 (en) | 2003-12-18 |
| DE60304040D1 (de) | 2006-05-11 |
| ZA200500214B (en) | 2006-02-22 |
| JP2005529170A (ja) | 2005-09-29 |
| AU2003273679A1 (en) | 2003-12-22 |
| PL371675A1 (en) | 2005-06-27 |
| ES2257680T3 (es) | 2006-08-01 |
| DE60304040T2 (de) | 2006-09-28 |
| MXPA04012209A (es) | 2005-02-25 |
| EP1512004B1 (de) | 2006-03-15 |
| BR0311720A (pt) | 2005-03-01 |
| RU2005100758A (ru) | 2006-01-20 |
| CN100401064C (zh) | 2008-07-09 |
| WO2003104803A3 (en) | 2004-04-15 |
| EP1512004A2 (de) | 2005-03-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1512014T3 (da) | Fremgangsmåder til identifikation af alloantigener samt anvendelse deraf til cancerbehandling og transplantation | |
| NO20014584L (no) | Proteinisolering og -analyse | |
| ATE441711T1 (de) | Peptide fähig die dimerisierung von c-jun zu inhibieren | |
| CY1110868T1 (el) | Ελαχιστη αλληλουχια dna που δρα ως μονωτης της χρωματινης και η χρηση της στην πρωτεϊνικη εκφραση | |
| DE60142689D1 (de) | Verwendung prokariotischer pest-ähnlicher peptide zur verstärkung der immunogenität von antigenen | |
| DE69833755D1 (de) | Verfahren zur herstellung von nicht-immunogenen proteinen | |
| ATE465178T1 (de) | Methoden zur amyloidentfernung mit anti-amyloid- antikörper | |
| HUP0202532A2 (hu) | Ko-stimulátor szignál-transzdukciós molekula (AILIM) elleni humán monoklonális antitest és gyógyászati alkalmazása | |
| DK1645631T3 (da) | Neisseria antigener og præparater | |
| BRPI0418286A (pt) | proteìnas de fusão de il-7 | |
| SI1644484T1 (sl) | Avtologne samo-toleranco inducirajoče celice monocitnega izvora in njihova uporaba v farmacevtskihpripravah | |
| DE60224291D1 (de) | System zur antikörperexpression und- synthese | |
| NO20063026L (no) | Antistoffer | |
| BRPI0411854A (pt) | veìculos protéicos para vacinas | |
| SG153874A1 (en) | Neutralizing epitope-based growth enhancing vaccine | |
| ATE517340T1 (de) | Sätze gegen kurze epitope gerichteter digitaler antikörper sowie diese verwendende verfahren | |
| DK1328547T3 (da) | Identifikation og modifikation af immundominante epitoper i polypeptider | |
| ATE460176T1 (de) | Mikrosomvakzin | |
| CY1117746T1 (el) | Αντιγονα αιμοφιλου της γριπης και αντιστοιχα θραυσματα dna | |
| ATE457352T1 (de) | Subtilisin-carlsberg-proteine mit verminderter immunogenität | |
| BRPI0513135A (pt) | bibliotecas de polinucleotìdeos, método de produção das mesmas, método de identificação de um polinucleotìdeo, região de ligação, meio adequado para uso em um, dispositivo eletrÈnico e dispositivo | |
| DE69933696D1 (de) | Cytokinrezeptor-kette | |
| ATE311443T1 (de) | Methoden zur durchforstung (screenen) von proteinen | |
| DE60315827D1 (de) | Verbesserte polysaccharid- und glykokonjugat-vakzine | |
| DE60304040D1 (de) | Methode zur identifizierung und eliminierung von t-zell epitopen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1512004 Country of ref document: EP |
|
| RZN | Patent revoked |