ATE412175T1 - Verwendung von kryptischen peptiden zur induktion von immunologischer toleranz - Google Patents

Verwendung von kryptischen peptiden zur induktion von immunologischer toleranz

Info

Publication number
ATE412175T1
ATE412175T1 AT05011041T AT05011041T ATE412175T1 AT E412175 T1 ATE412175 T1 AT E412175T1 AT 05011041 T AT05011041 T AT 05011041T AT 05011041 T AT05011041 T AT 05011041T AT E412175 T1 ATE412175 T1 AT E412175T1
Authority
AT
Austria
Prior art keywords
immunological tolerance
induce immunological
cryptic peptides
cryptic
peptides
Prior art date
Application number
AT05011041T
Other languages
English (en)
Inventor
Anthony Barrington Kay
Mark Larche
Original Assignee
Circassia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9605904.3A external-priority patent/GB9605904D0/en
Priority claimed from GBGB9608430.6A external-priority patent/GB9608430D0/en
Application filed by Circassia Ltd filed Critical Circassia Ltd
Application granted granted Critical
Publication of ATE412175T1 publication Critical patent/ATE412175T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43531Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047Cells of the immune system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047Cells of the immune system
    • G01N33/505Cells of the immune system involving T-cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56972White blood cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Insects & Arthropods (AREA)
  • Mycology (AREA)
  • Botany (AREA)
AT05011041T 1996-03-21 1997-03-20 Verwendung von kryptischen peptiden zur induktion von immunologischer toleranz ATE412175T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9605904.3A GB9605904D0 (en) 1996-03-21 1996-03-21 Peptides
GBGB9608430.6A GB9608430D0 (en) 1996-04-24 1996-04-24 Peptides

Publications (1)

Publication Number Publication Date
ATE412175T1 true ATE412175T1 (de) 2008-11-15

Family

ID=26308965

Family Applications (2)

Application Number Title Priority Date Filing Date
AT97908389T ATE296444T1 (de) 1996-03-21 1997-03-20 Kryptische peptide und verfahren zu ihrer identifizierung
AT05011041T ATE412175T1 (de) 1996-03-21 1997-03-20 Verwendung von kryptischen peptiden zur induktion von immunologischer toleranz

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT97908389T ATE296444T1 (de) 1996-03-21 1997-03-20 Kryptische peptide und verfahren zu ihrer identifizierung

Country Status (11)

Country Link
US (1) US6737406B1 (de)
EP (2) EP1612555B1 (de)
JP (1) JP4340329B2 (de)
AT (2) ATE296444T1 (de)
AU (1) AU730198C (de)
CA (1) CA2247009C (de)
DE (2) DE69733343D1 (de)
DK (1) DK1612555T3 (de)
ES (1) ES2314515T3 (de)
GB (3) GB2326642B (de)
WO (1) WO1997035193A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2812087B1 (fr) 2000-07-21 2007-05-11 Inst Nat Sante Rech Med Procede de criblage de peptides utilisables en immunotherapie
WO2002066979A1 (en) * 2001-02-22 2002-08-29 Takara Bio Inc. Method of detecting antigen causative of bronchial asthma
RU2334235C2 (ru) * 2002-06-11 2008-09-20 Мерк Патент Гмбх Способ картирования и устранения эпитопов т-клеток
GB0710529D0 (en) 2007-06-01 2007-07-11 Circassia Ltd Vaccine
MX2010001779A (es) * 2007-08-15 2010-07-06 Circassia Ltd Peptidos para vacunas.
WO2025194374A1 (zh) * 2024-03-20 2025-09-25 深圳赫兹生命科学技术有限公司 猫过敏原多肽片段及应用

Family Cites Families (34)

* Cited by examiner, † Cited by third party
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KR880701108A (ko) 1986-06-30 1988-07-25 원본미기재 면역조절 조성물 및 이들의 용도
US5019384A (en) 1986-06-30 1991-05-28 Massachusetts Institute Of Technology Immunonodulating compositions and their use
US6180368B1 (en) 1988-03-23 2001-01-30 University Of Melbourne Ryegrass pollen allergen
EP0463059B1 (de) 1989-03-17 1998-12-30 Immulogic Pharmaceutical Corporation Allergene proteine aus ambrosia und verwendung davon
US5328991A (en) 1989-11-03 1994-07-12 Immulogic Pharmaceutical Corp. Preparation of alkali-modified cat dander allergen (Fel d I) for immunotherapeutic purposes
US5547669A (en) 1989-11-03 1996-08-20 Immulogic Pharma Corp Recombinant peptides comprising T cell epitopes of the cat allergen, Fel d I
AU650249B2 (en) 1989-11-03 1994-06-16 Immulogic Pharmaceutical Corporation A human T cell reactive feline protein (TRFP) isolated from house dust and uses therefor
US6019972A (en) 1989-11-03 2000-02-01 Immulogic Pharmaceutical Corporation Peptides of human T cell reactive feline protein (TRFP)
US5433948A (en) 1990-02-13 1995-07-18 Thomas; Wayne R. Cloning and sequencing of allergens of dermatophagoides (house dust mite)
ATE178940T1 (de) 1990-09-11 1999-04-15 Inst Child Health Research Klonierung und sequenzierung von dermatophagoiden-antigenen (hausstaubmilben)
JPH06506056A (ja) 1990-10-30 1994-07-07 イミュロジック ファーマシューティカル コーポレイション Mhc抗原によるペプチド結合検定法
WO1992011859A1 (en) 1991-01-08 1992-07-23 Immulogic Pharmaceutical Corporation Peptide-mediated hyposensitization of the human t cell response to dermatophagoides spp. (house dust mite)
WO1994001560A1 (en) 1991-07-12 1994-01-20 Immulogic Pharmaceutical Corporation Allergenic proteins and peptides from japanese cedar pollen
CA2112913A1 (en) 1991-07-12 1993-01-21 Irwin J. Griffith Allergenic proteins and peptides from japanese cedar pollen
NZ244782A (en) * 1991-10-16 1996-12-20 Immulogic Pharma Corp Isolated peptides having t-cell stimulating activity, pharmaceutical composition
ATE444360T1 (de) 1991-10-16 2009-10-15 Merck Patent Gmbh T-zell epitopen von den wichtigsten allergene von dermatophagoides (hausmilbe)
WO1994024281A1 (en) 1993-04-14 1994-10-27 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from dermatophagoides (house dust mite)
IL105153A (en) 1992-03-25 1999-12-22 Immulogic Pharma Corp Therapeutic compositions comprising peptides derived from human t cell reactive feline protein
EP0770681A3 (de) 1992-04-09 1997-06-04 Immulogic Pharmaceutical Corporation T-Zellen Epitopen der Hauptallergenen von Ambrosia artemisiifolia
AU4796393A (en) 1992-07-31 1994-03-03 Immulogic Pharmaceutical Corporation Sensitive assay for antigens and antibodies and its use to identify rheumatoid arthritis antigen
WO1994011512A2 (en) 1992-11-12 1994-05-26 Immulogic Pharmaceutical Corporation Allergenic proteins and peptides from japanese cedar pollen
ATE318902T1 (de) 1992-12-31 2006-03-15 Immulogic Pharma Corp Allergene proteine und peptide von hundhautanhangsgebilden und ihre verwendung
WO1994021675A2 (en) 1993-03-12 1994-09-29 Immulogic Pharmaceutical Corporation T cell epitopes of ryegrass pollen allergen
NZ266739A (en) 1993-06-02 1997-07-27 Tvw Telethon Inst Child Health Inducing immunologic tolerance by administering a cryptic peptide derived from the antigen der pi
WO1995001597A2 (en) 1993-07-01 1995-01-12 British Telecomm System for generating instructions for speech application
FI960629L (fi) 1993-08-13 1996-04-12 Immulogic Pharma Corp Raiheinäsiitepöly allergeenin T-soluepitoopit
AU2238395A (en) 1994-04-01 1995-10-23 Immulogic Pharmaceutical Corporation Haptenated peptides and uses thereof
ES2285703T3 (es) 1994-04-14 2007-11-16 Merck Patent Gmbh Formulaciones farmaceuticas de peptidos para el tratamiento de alergia a los acaros del polvo.
JPH10505356A (ja) * 1994-09-02 1998-05-26 イミユロジク・フアーマシユーチカル・コーポレーシヨン ヒトへの投与のための組成物および方法、抗原特異的免疫応答のダウンレギュレーションを行うことが可能なペプチド
CZ122697A3 (en) 1994-10-25 1997-09-17 Immulogic Pharma Corp Preparations and methods of treating disseminated sclerosis
AU4146796A (en) 1994-10-27 1996-05-23 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from ambrosia artemisiifolia
WO1996020950A2 (en) 1995-01-06 1996-07-11 Immulogic Pharmaceutical Corporation Compositions and methods for treating rheumatoid arthritis
US6719976B1 (en) 1996-03-10 2004-04-13 Meiji Milk Products Co., Ltd. Peptide-based immunotherapeutic agent for treating allergic diseases
US5804201A (en) 1996-03-11 1998-09-08 The Rockefeller University Immunomodulatory peptides of vespid antigen 5

Also Published As

Publication number Publication date
DE69733343D1 (de) 2005-06-30
GB2349463A (en) 2000-11-01
CA2247009C (en) 2009-08-04
JP2000508627A (ja) 2000-07-11
GB2352518A (en) 2001-01-31
DE69739062D1 (de) 2008-12-04
EP0888541B1 (de) 2005-05-25
GB2352518B (en) 2001-04-04
GB0027373D0 (en) 2000-12-27
EP0888541A1 (de) 1999-01-07
GB2349463B (en) 2001-01-10
WO1997035193A1 (en) 1997-09-25
ATE296444T1 (de) 2005-06-15
AU730198C (en) 2002-03-14
AU730198B2 (en) 2001-03-01
JP4340329B2 (ja) 2009-10-07
GB0020260D0 (en) 2000-10-04
CA2247009A1 (en) 1997-09-25
EP1612555B1 (de) 2008-10-22
GB9817461D0 (en) 1998-10-07
EP1612555A1 (de) 2006-01-04
AU2036597A (en) 1997-10-10
GB2326642A (en) 1998-12-30
ES2314515T3 (es) 2009-03-16
US6737406B1 (en) 2004-05-18
GB2326642B (en) 2001-02-07
DK1612555T3 (da) 2009-02-09

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