ATE296444T1 - Kryptische peptide und verfahren zu ihrer identifizierung - Google Patents

Kryptische peptide und verfahren zu ihrer identifizierung

Info

Publication number
ATE296444T1
ATE296444T1 AT97908389T AT97908389T ATE296444T1 AT E296444 T1 ATE296444 T1 AT E296444T1 AT 97908389 T AT97908389 T AT 97908389T AT 97908389 T AT97908389 T AT 97908389T AT E296444 T1 ATE296444 T1 AT E296444T1
Authority
AT
Austria
Prior art keywords
identifying
cryptic peptides
cryptic
peptides
peptide
Prior art date
Application number
AT97908389T
Other languages
English (en)
Inventor
Anthony Kay
Mark Larche
Original Assignee
Circassia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9605904.3A external-priority patent/GB9605904D0/en
Priority claimed from GBGB9608430.6A external-priority patent/GB9608430D0/en
Application filed by Circassia Ltd filed Critical Circassia Ltd
Application granted granted Critical
Publication of ATE296444T1 publication Critical patent/ATE296444T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Insects & Arthropods (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
AT97908389T 1996-03-21 1997-03-20 Kryptische peptide und verfahren zu ihrer identifizierung ATE296444T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9605904.3A GB9605904D0 (en) 1996-03-21 1996-03-21 Peptides
GBGB9608430.6A GB9608430D0 (en) 1996-04-24 1996-04-24 Peptides
PCT/GB1997/000783 WO1997035193A1 (en) 1996-03-21 1997-03-20 Cryptic peptides and method for their identification

Publications (1)

Publication Number Publication Date
ATE296444T1 true ATE296444T1 (de) 2005-06-15

Family

ID=26308965

Family Applications (2)

Application Number Title Priority Date Filing Date
AT97908389T ATE296444T1 (de) 1996-03-21 1997-03-20 Kryptische peptide und verfahren zu ihrer identifizierung
AT05011041T ATE412175T1 (de) 1996-03-21 1997-03-20 Verwendung von kryptischen peptiden zur induktion von immunologischer toleranz

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT05011041T ATE412175T1 (de) 1996-03-21 1997-03-20 Verwendung von kryptischen peptiden zur induktion von immunologischer toleranz

Country Status (11)

Country Link
US (1) US6737406B1 (de)
EP (2) EP0888541B1 (de)
JP (1) JP4340329B2 (de)
AT (2) ATE296444T1 (de)
AU (1) AU730198C (de)
CA (1) CA2247009C (de)
DE (2) DE69733343D1 (de)
DK (1) DK1612555T3 (de)
ES (1) ES2314515T3 (de)
GB (3) GB2349463B (de)
WO (1) WO1997035193A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2812087B1 (fr) * 2000-07-21 2007-05-11 Inst Nat Sante Rech Med Procede de criblage de peptides utilisables en immunotherapie
WO2002066979A1 (fr) * 2001-02-22 2002-08-29 Takara Bio Inc. Procede de detection d'un antigene responsable de l'asthme
MXPA04012209A (es) * 2002-06-11 2005-02-25 Merck Patent Gmbh Metodo para mapear y eliminar epitopos de linfocitos t.
GB0710529D0 (en) 2007-06-01 2007-07-11 Circassia Ltd Vaccine
US9340580B2 (en) 2007-08-15 2016-05-17 Circassia Limited Peptide with multiple epitopes

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019384A (en) 1986-06-30 1991-05-28 Massachusetts Institute Of Technology Immunonodulating compositions and their use
KR880701108A (ko) 1986-06-30 1988-07-25 원본미기재 면역조절 조성물 및 이들의 용도
US6180368B1 (en) 1988-03-23 2001-01-30 University Of Melbourne Ryegrass pollen allergen
JP3220451B2 (ja) 1989-03-17 2001-10-22 イミユロジク・フアーマシユーチカル・コーポレーシヨン ブタクサからのアレルゲン蛋白質およびそれらの使用
DK0500785T3 (da) * 1989-11-03 2002-08-19 Immulogic Pharma Corp Humant T-celleaktivitet felint protein (TRFP) isoleret fra husstøv samt anvendelser heraf
US6019972A (en) * 1989-11-03 2000-02-01 Immulogic Pharmaceutical Corporation Peptides of human T cell reactive feline protein (TRFP)
US5328991A (en) 1989-11-03 1994-07-12 Immulogic Pharmaceutical Corp. Preparation of alkali-modified cat dander allergen (Fel d I) for immunotherapeutic purposes
US5547669A (en) 1989-11-03 1996-08-20 Immulogic Pharma Corp Recombinant peptides comprising T cell epitopes of the cat allergen, Fel d I
US5433948A (en) 1990-02-13 1995-07-18 Thomas; Wayne R. Cloning and sequencing of allergens of dermatophagoides (house dust mite)
ATE178940T1 (de) 1990-09-11 1999-04-15 Inst Child Health Research Klonierung und sequenzierung von dermatophagoiden-antigenen (hausstaubmilben)
WO1992007952A1 (en) 1990-10-30 1992-05-14 Immulogic Pharmaceutical Corporation Peptide binding assays with mhc antigens
WO1992011859A1 (en) 1991-01-08 1992-07-23 Immulogic Pharmaceutical Corporation Peptide-mediated hyposensitization of the human t cell response to dermatophagoides spp. (house dust mite)
WO1994001560A1 (en) 1991-07-12 1994-01-20 Immulogic Pharmaceutical Corporation Allergenic proteins and peptides from japanese cedar pollen
AU2300492A (en) 1991-07-12 1993-02-11 Immulogic Pharmaceutical Corporation Allergenic proteins and peptides from japanese cedar pollen
ATE382699T1 (de) * 1991-10-16 2008-01-15 Merck Patent Gmbh Verfahren zum entwurf von rekombitopen peptiden
WO1994024281A1 (en) 1993-04-14 1994-10-27 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from dermatophagoides (house dust mite)
WO1993008279A1 (en) 1991-10-16 1993-04-29 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from dermatophagoides (house dust mite)
IL105153A (en) 1992-03-25 1999-12-22 Immulogic Pharma Corp Therapeutic compositions comprising peptides derived from human t cell reactive feline protein
NZ252013A (en) 1992-04-09 1996-08-27 Immulogic Pharma Corp T cell receptor epitopes for short ragweed pollen
AU4796393A (en) 1992-07-31 1994-03-03 Immulogic Pharmaceutical Corporation Sensitive assay for antigens and antibodies and its use to identify rheumatoid arthritis antigen
CA2148713A1 (en) 1992-11-12 1994-05-26 Mei-Chang Kuo Allergenic proteins and peptides from japanese cedar pollen
DE69333985T2 (de) 1992-12-31 2006-11-23 Immulogic Pharmaceutical Corp., Waltham Allergene proteine und peptide von hundhautanhangsgebilden und ihre verwendung
NZ263913A (en) 1993-03-12 1997-10-24 Immulogic Pharma Corp Lol pi protein allergen from ryegrass and related peptides coding sequences, vectors, protein production and use
EP0705108A4 (de) * 1993-06-02 1997-08-06 Tvw Telethon Inst Child Health Verwendung von kryptischen peptiden zur induktion immunologisches toleranz
AU7559794A (en) 1993-08-13 1995-03-22 Immulogic Pharmaceutical Corporation T cell epitopes of ryegrass pollen allergen
WO1995026980A2 (en) 1994-04-01 1995-10-12 Immulogic Pharmaceutical Corporation Haptenated peptides and uses thereof
NZ284637A (en) 1994-04-14 1998-09-24 Immulogic Pharma Corp Pharmaceutical formulations for treating dust mite allergy
CZ63297A3 (en) * 1994-09-02 1997-08-13 Immulogic Pharma Corp Peptide preparations capable of attenuating antigen specific immune response
CZ122697A3 (en) 1994-10-25 1997-09-17 Immulogic Pharma Corp Preparations and methods of treating disseminated sclerosis
AU4146796A (en) 1994-10-27 1996-05-23 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from ambrosia artemisiifolia
AU4695296A (en) 1995-01-06 1996-07-24 Immulogic Pharmaceutical Corporation Compositions and methods for treating rheumatoid arthritis
CN1330377C (zh) 1996-03-10 2007-08-08 明治乳业株式会社 用于治疗变态反应疾病的基于肽的免疫治疗剂
US5804201A (en) 1996-03-11 1998-09-08 The Rockefeller University Immunomodulatory peptides of vespid antigen 5

Also Published As

Publication number Publication date
ES2314515T3 (es) 2009-03-16
DE69739062D1 (de) 2008-12-04
GB9817461D0 (en) 1998-10-07
EP1612555A1 (de) 2006-01-04
WO1997035193A1 (en) 1997-09-25
AU730198C (en) 2002-03-14
EP1612555B1 (de) 2008-10-22
EP0888541A1 (de) 1999-01-07
EP0888541B1 (de) 2005-05-25
GB2326642B (en) 2001-02-07
GB2352518A (en) 2001-01-31
GB2326642A (en) 1998-12-30
JP4340329B2 (ja) 2009-10-07
GB2349463A (en) 2000-11-01
GB2349463B (en) 2001-01-10
AU730198B2 (en) 2001-03-01
GB2352518B (en) 2001-04-04
ATE412175T1 (de) 2008-11-15
GB0027373D0 (en) 2000-12-27
DK1612555T3 (da) 2009-02-09
DE69733343D1 (de) 2005-06-30
CA2247009C (en) 2009-08-04
JP2000508627A (ja) 2000-07-11
US6737406B1 (en) 2004-05-18
GB0020260D0 (en) 2000-10-04
AU2036597A (en) 1997-10-10
CA2247009A1 (en) 1997-09-25

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