ZA200307737B - Methods and compositions for making emamectin. - Google Patents

Methods and compositions for making emamectin. Download PDF

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Publication number
ZA200307737B
ZA200307737B ZA200307737A ZA200307737A ZA200307737B ZA 200307737 B ZA200307737 B ZA 200307737B ZA 200307737 A ZA200307737 A ZA 200307737A ZA 200307737 A ZA200307737 A ZA 200307737A ZA 200307737 B ZA200307737 B ZA 200307737B
Authority
ZA
South Africa
Prior art keywords
seq
nucleic acid
avermectin
polypeptide
formula
Prior art date
Application number
ZA200307737A
Other languages
English (en)
Inventor
Istvan Molnar
Ligon James Madison
Zirkle Ross Eric
Philip Eugene Hammer
Hill Dwight Steven
Pachlatko Johannes Paul
Buckel Thomas Guenter
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of ZA200307737B publication Critical patent/ZA200307737B/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
ZA200307737A 2001-05-16 2003-10-03 Methods and compositions for making emamectin. ZA200307737B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29114901P 2001-05-16 2001-05-16

Publications (1)

Publication Number Publication Date
ZA200307737B true ZA200307737B (en) 2004-04-21

Family

ID=23119055

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200307737A ZA200307737B (en) 2001-05-16 2003-10-03 Methods and compositions for making emamectin.

Country Status (17)

Country Link
US (1) US20030068788A1 (es)
EP (1) EP1389239A2 (es)
JP (1) JP2004529651A (es)
KR (1) KR20040005963A (es)
CN (1) CN1514880A (es)
AR (1) AR034703A1 (es)
AU (1) AU2002342337B2 (es)
BR (1) BR0209813A (es)
CA (1) CA2446130A1 (es)
CZ (1) CZ20033078A3 (es)
HU (1) HUP0400008A2 (es)
IL (1) IL158764A0 (es)
MX (1) MXPA03010381A (es)
PL (1) PL367195A1 (es)
RU (1) RU2003135646A (es)
WO (1) WO2002092801A2 (es)
ZA (1) ZA200307737B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1500704B1 (en) * 2002-04-12 2009-03-25 Mercian Corporation Expression system of actinomycete-origin cytochrome p-450 in escherichia coli
EP1705247A4 (en) 2003-11-27 2008-08-20 Mercian Corp DNA ACCOMPANYING HYDROXYLATION OF A MAKROLIDE COMPOUND
JP4599357B2 (ja) 2004-07-20 2010-12-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 プラジエノライドの生合成に関与するポリペプチドをコードするdna
AU2006100665B4 (en) * 2006-07-06 2006-09-07 Wyeth Biocatalytic oxidation process and use thereof
WO2008096695A1 (ja) * 2007-02-05 2008-08-14 Mercian Corporation ビタミンd類の水酸化に関連するdna
CN112176000B (zh) * 2013-09-19 2024-09-10 弗门尼舍有限公司 用于生产芳香醇的方法
JP6522551B2 (ja) 2016-06-10 2019-05-29 長谷川香料株式会社 (−)−ロタンドンの製造方法
GB201807815D0 (en) 2018-05-14 2018-06-27 Hypha Discovery Ltd Hydroxylation techniques
GB201819209D0 (en) 2018-11-26 2019-01-09 Hypha Discovery Ltd Biocatalytic techniques
CN110305818A (zh) * 2019-08-15 2019-10-08 齐鲁制药(内蒙古)有限公司 一种阿维菌素菌种选育方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4427663A (en) * 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
US4874749A (en) * 1987-07-31 1989-10-17 Merck & Co., Inc. 4"-Deoxy-4-N-methylamino avermectin Bla/Blb
WO1993012236A1 (en) * 1991-12-16 1993-06-24 E.I. Du Pont De Nemours And Company Constitutive expression of p450soy and ferredoxin-soy in streptomyces, and biotransformation of chemicals by recombinant organisms
US5399717A (en) * 1993-09-29 1995-03-21 Merck & Co., Inc. Glycosidation route to 4"-epi-methylamino-4"-deoxyavermectin B1
US6117659A (en) * 1997-04-30 2000-09-12 Kosan Biosciences, Inc. Recombinant narbonolide polyketide synthase
US6265202B1 (en) * 1998-06-26 2001-07-24 Regents Of The University Of Minnesota DNA encoding methymycin and pikromycin
GB9926887D0 (en) * 1999-11-12 2000-01-12 Novartis Ag Organic compounds
JP2002058490A (ja) * 2000-08-22 2002-02-26 Kyowa Hakko Kogyo Co Ltd 新規チトクロームp450

Also Published As

Publication number Publication date
BR0209813A (pt) 2004-06-01
IL158764A0 (en) 2004-05-12
AU2002342337B2 (en) 2006-01-05
CA2446130A1 (en) 2002-11-21
US20030068788A1 (en) 2003-04-10
HUP0400008A2 (hu) 2004-04-28
CN1514880A (zh) 2004-07-21
JP2004529651A (ja) 2004-09-30
RU2003135646A (ru) 2005-05-10
AR034703A1 (es) 2004-03-17
MXPA03010381A (es) 2004-03-16
KR20040005963A (ko) 2004-01-16
WO2002092801A2 (en) 2002-11-21
EP1389239A2 (en) 2004-02-18
CZ20033078A3 (cs) 2004-02-18
WO2002092801A3 (en) 2003-11-27
PL367195A1 (en) 2005-02-21

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