ZA200304647B - Conjugates of erythropoietin (EPO) with polyethylene glycol (PEG). - Google Patents
Conjugates of erythropoietin (EPO) with polyethylene glycol (PEG). Download PDFInfo
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- ZA200304647B ZA200304647B ZA200304647A ZA200304647A ZA200304647B ZA 200304647 B ZA200304647 B ZA 200304647B ZA 200304647 A ZA200304647 A ZA 200304647A ZA 200304647 A ZA200304647 A ZA 200304647A ZA 200304647 B ZA200304647 B ZA 200304647B
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- South Africa
- Prior art keywords
- thr
- conjugate
- asn
- epo
- glycoprotein
- Prior art date
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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Landscapes
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00127891 | 2000-12-20 |
Publications (1)
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| ZA200304647B true ZA200304647B (en) | 2004-09-13 |
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| ZA200304647A ZA200304647B (en) | 2000-12-20 | 2003-06-13 | Conjugates of erythropoietin (EPO) with polyethylene glycol (PEG). |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7128913B2 (https=) |
| JP (2) | JP4656814B2 (https=) |
| KR (1) | KR100645843B1 (https=) |
| CN (1) | CN100528235C (https=) |
| AR (1) | AR035407A1 (https=) |
| AU (2) | AU2002233230B2 (https=) |
| BR (1) | BR0116381A (https=) |
| CA (1) | CA2431964C (https=) |
| ES (1) | ES2361824T3 (https=) |
| MX (1) | MXPA03005406A (https=) |
| ZA (1) | ZA200304647B (https=) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL131959A0 (en) * | 1997-03-18 | 2001-03-19 | Roche Diagnostics Gmbh | Pharmaceutical combined preparations containing erythropoietin and iron preparations |
| US7304150B1 (en) * | 1998-10-23 | 2007-12-04 | Amgen Inc. | Methods and compositions for the prevention and treatment of anemia |
| ME00673B (me) * | 2000-05-15 | 2011-12-20 | Hoffmann La Roche | Nova farmaceutska smjesa |
| AU2002233230B2 (en) * | 2000-12-20 | 2007-02-01 | F. Hoffmann-La Roche Ag | Erythropoietin conjugates |
| WO2002061064A2 (de) * | 2001-02-01 | 2002-08-08 | Roche Diagnostics Gmbh | Verfahren zur herstellung von rekombinantem trypsin |
| EP1234583A1 (en) | 2001-02-23 | 2002-08-28 | F. Hoffmann-La Roche Ag | PEG-conjugates of HGF-NK4 |
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-
2001
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- 2001-12-08 MX MXPA03005406A patent/MXPA03005406A/es active IP Right Grant
- 2001-12-08 ES ES01984811T patent/ES2361824T3/es not_active Expired - Lifetime
- 2001-12-08 KR KR1020037008299A patent/KR100645843B1/ko not_active Expired - Fee Related
- 2001-12-08 CA CA2431964A patent/CA2431964C/en not_active Expired - Lifetime
- 2001-12-08 AU AU3323002A patent/AU3323002A/xx active Pending
- 2001-12-08 BR BR0116381-7A patent/BR0116381A/pt not_active IP Right Cessation
- 2001-12-08 JP JP2002551010A patent/JP4656814B2/ja not_active Expired - Lifetime
- 2001-12-08 CN CNB018206093A patent/CN100528235C/zh not_active Expired - Lifetime
- 2001-12-11 US US10/014,363 patent/US7128913B2/en not_active Expired - Lifetime
- 2001-12-18 AR ARP010105862A patent/AR035407A1/es unknown
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2003
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2004525097A (ja) | 2004-08-19 |
| AU2002233230B2 (en) | 2007-02-01 |
| JP4563434B2 (ja) | 2010-10-13 |
| CN100528235C (zh) | 2009-08-19 |
| KR100645843B1 (ko) | 2006-11-14 |
| BR0116381A (pt) | 2004-02-25 |
| US7128913B2 (en) | 2006-10-31 |
| KR20030074667A (ko) | 2003-09-19 |
| AU3323002A (en) | 2002-07-01 |
| CA2431964A1 (en) | 2002-06-27 |
| JP2008069155A (ja) | 2008-03-27 |
| JP4656814B2 (ja) | 2011-03-23 |
| AR035407A1 (es) | 2004-05-26 |
| ES2361824T3 (es) | 2011-06-22 |
| MXPA03005406A (es) | 2003-09-25 |
| CN1527726A (zh) | 2004-09-08 |
| US20020115833A1 (en) | 2002-08-22 |
| CA2431964C (en) | 2013-09-10 |
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