ZA200303089B - Cosmetic method of treating skin. - Google Patents
Cosmetic method of treating skin. Download PDFInfo
- Publication number
- ZA200303089B ZA200303089B ZA200303089A ZA200303089A ZA200303089B ZA 200303089 B ZA200303089 B ZA 200303089B ZA 200303089 A ZA200303089 A ZA 200303089A ZA 200303089 A ZA200303089 A ZA 200303089A ZA 200303089 B ZA200303089 B ZA 200303089B
- Authority
- ZA
- South Africa
- Prior art keywords
- skin
- prenylnaringenin
- decorin
- boosting
- cosmetic
- Prior art date
Links
- 239000002537 cosmetic Substances 0.000 title claims abstract description 19
- 238000000034 method Methods 0.000 title claims abstract description 19
- LPEPZZAVFJPLNZ-SFHVURJKSA-N sophoraflavanone B Chemical compound C1([C@@H]2CC(=O)C=3C(O)=CC(O)=C(C=3O2)CC=C(C)C)=CC=C(O)C=C1 LPEPZZAVFJPLNZ-SFHVURJKSA-N 0.000 claims abstract description 53
- 239000000203 mixture Substances 0.000 claims abstract description 33
- YHWNASRGLKJRJJ-UHFFFAOYSA-N sophoraflavanone B Natural products C1C(=O)C2=C(O)C(CC=C(C)C)=C(O)C=C2OC1C1=CC=C(O)C=C1 YHWNASRGLKJRJJ-UHFFFAOYSA-N 0.000 claims abstract description 26
- 230000000699 topical effect Effects 0.000 claims abstract description 15
- 206010051246 Photodermatosis Diseases 0.000 claims abstract description 11
- 102000004237 Decorin Human genes 0.000 claims description 24
- 108090000738 Decorin Proteins 0.000 claims description 24
- 230000008901 benefit Effects 0.000 claims description 14
- 238000007665 sagging Methods 0.000 claims description 7
- 108010035532 Collagen Proteins 0.000 claims description 6
- 102000008186 Collagen Human genes 0.000 claims description 6
- 229920001436 collagen Polymers 0.000 claims description 6
- 230000037307 sensitive skin Effects 0.000 claims description 6
- 230000036548 skin texture Effects 0.000 claims description 5
- 210000002950 fibroblast Anatomy 0.000 description 19
- 210000004027 cell Anatomy 0.000 description 12
- XEYBRNLFEZDVAW-ARSRFYASSA-N dinoprostone Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 description 11
- 238000012360 testing method Methods 0.000 description 10
- 229960002986 dinoprostone Drugs 0.000 description 9
- 230000002500 effect on skin Effects 0.000 description 9
- 239000012528 membrane Substances 0.000 description 9
- XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 description 9
- 108010050808 Procollagen Proteins 0.000 description 8
- 206010040954 Skin wrinkling Diseases 0.000 description 8
- 238000003556 assay Methods 0.000 description 8
- 210000002966 serum Anatomy 0.000 description 8
- 230000015572 biosynthetic process Effects 0.000 description 7
- 239000003075 phytoestrogen Substances 0.000 description 7
- 238000003786 synthesis reaction Methods 0.000 description 7
- 230000003712 anti-aging effect Effects 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 5
- 239000003636 conditioned culture medium Substances 0.000 description 5
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 5
- 239000002609 medium Substances 0.000 description 5
- 229930002330 retinoic acid Natural products 0.000 description 5
- 229960001727 tretinoin Drugs 0.000 description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- BELBBZDIHDAJOR-UHFFFAOYSA-N Phenolsulfonephthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2S(=O)(=O)O1 BELBBZDIHDAJOR-UHFFFAOYSA-N 0.000 description 4
- 229920001213 Polysorbate 20 Polymers 0.000 description 4
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 description 4
- 230000008021 deposition Effects 0.000 description 4
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- 229960003531 phenolsulfonphthalein Drugs 0.000 description 4
- 230000008845 photoaging Effects 0.000 description 4
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 4
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 4
- 238000011282 treatment Methods 0.000 description 4
- 230000003827 upregulation Effects 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
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- 230000008439 repair process Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- SAMYFBLRCRWESN-UHFFFAOYSA-N 16-methylheptadecyl hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCCCC(C)C SAMYFBLRCRWESN-UHFFFAOYSA-N 0.000 description 2
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 2
- 235000008694 Humulus lupulus Nutrition 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 2
- 238000010306 acid treatment Methods 0.000 description 2
- 239000000872 buffer Substances 0.000 description 2
- 229910002092 carbon dioxide Inorganic materials 0.000 description 2
- 239000001569 carbon dioxide Substances 0.000 description 2
- 229960000541 cetyl alcohol Drugs 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 230000002542 deteriorative effect Effects 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 210000003953 foreskin Anatomy 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 230000003810 hyperpigmentation Effects 0.000 description 2
- 208000000069 hyperpigmentation Diseases 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 230000003389 potentiating effect Effects 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 229940108325 retinyl palmitate Drugs 0.000 description 2
- 235000019172 retinyl palmitate Nutrition 0.000 description 2
- 239000011769 retinyl palmitate Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000011550 stock solution Substances 0.000 description 2
- LQIAZOCLNBBZQK-UHFFFAOYSA-N 1-(1,2-Diphosphanylethyl)pyrrolidin-2-one Chemical compound PCC(P)N1CCCC1=O LQIAZOCLNBBZQK-UHFFFAOYSA-N 0.000 description 1
- ZIIUUSVHCHPIQD-UHFFFAOYSA-N 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide Chemical compound CC1=CC(C)=CC(C)=C1S(=O)(=O)NC1=CC=CC(C(F)(F)F)=C1 ZIIUUSVHCHPIQD-UHFFFAOYSA-N 0.000 description 1
- 239000004322 Butylated hydroxytoluene Substances 0.000 description 1
- 229920000298 Cellophane Polymers 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 101001000206 Homo sapiens Decorin Proteins 0.000 description 1
- 108010001336 Horseradish Peroxidase Proteins 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 102000015439 Phospholipases Human genes 0.000 description 1
- 108010064785 Phospholipases Proteins 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- VYGQUTWHTHXGQB-UHFFFAOYSA-N Retinol hexadecanoate Natural products CCCCCCCCCCCCCCCC(=O)OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-UHFFFAOYSA-N 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- QPMSXSBEVQLBIL-CZRHPSIPSA-N ac1mix0p Chemical compound C1=CC=C2N(C[C@H](C)CN(C)C)C3=CC(OC)=CC=C3SC2=C1.O([C@H]1[C@]2(OC)C=CC34C[C@@H]2[C@](C)(O)CCC)C2=C5[C@]41CCN(C)[C@@H]3CC5=CC=C2O QPMSXSBEVQLBIL-CZRHPSIPSA-N 0.000 description 1
- NFXWJYUDIOHFAW-UHFFFAOYSA-N acetic acid;tetradecanoic acid Chemical compound CC(O)=O.CCCCCCCCCCCCCC(O)=O NFXWJYUDIOHFAW-UHFFFAOYSA-N 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 238000004378 air conditioning Methods 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 235000013405 beer Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008436 biogenesis Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 235000010354 butylated hydroxytoluene Nutrition 0.000 description 1
- 229940095259 butylated hydroxytoluene Drugs 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 239000007854 depigmenting agent Substances 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 229940008099 dimethicone Drugs 0.000 description 1
- 239000004205 dimethyl polysiloxane Substances 0.000 description 1
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 239000002270 dispersing agent Substances 0.000 description 1
- VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 description 1
- 229940096118 ella Drugs 0.000 description 1
- 239000003974 emollient agent Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000001076 estrogenic effect Effects 0.000 description 1
- 235000013861 fat-free Nutrition 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 102000045840 human DCN Human genes 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 239000008309 hydrophilic cream Substances 0.000 description 1
- 238000010191 image analysis Methods 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000000411 inducer Substances 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000028709 inflammatory response Effects 0.000 description 1
- 229940113915 isostearyl palmitate Drugs 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000000329 molecular dynamics simulation Methods 0.000 description 1
- 230000003990 molecular pathway Effects 0.000 description 1
- 230000037311 normal skin Effects 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 239000003605 opacifier Substances 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 235000008476 powdered milk Nutrition 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000037333 procollagen synthesis Effects 0.000 description 1
- 230000000770 proinflammatory effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 150000003180 prostaglandins Chemical class 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000011506 response to oxidative stress Effects 0.000 description 1
- 238000013207 serial dilution Methods 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 230000037075 skin appearance Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000000475 sunscreen effect Effects 0.000 description 1
- 239000000516 sunscreening agent Substances 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- OOLLAFOLCSJHRE-ZHAKMVSLSA-N ulipristal acetate Chemical compound C1=CC(N(C)C)=CC=C1[C@@H]1C2=C3CCC(=O)C=C3CC[C@H]2[C@H](CC[C@]2(OC(C)=O)C(C)=O)[C@]2(C)C1 OOLLAFOLCSJHRE-ZHAKMVSLSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0027769.9A GB0027769D0 (en) | 2000-11-14 | 2000-11-14 | Cosmetic method of treating skin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200303089B true ZA200303089B (en) | 2004-04-22 |
Family
ID=9903147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200303089A ZA200303089B (en) | 2000-11-14 | 2003-04-22 | Cosmetic method of treating skin. |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1333805B1 (fr) |
| JP (1) | JP2004513902A (fr) |
| KR (1) | KR100847609B1 (fr) |
| CN (1) | CN1217652C (fr) |
| AT (1) | ATE322314T1 (fr) |
| AU (2) | AU2002220679B9 (fr) |
| BR (1) | BR0115389A (fr) |
| CA (1) | CA2426467C (fr) |
| CZ (1) | CZ299342B6 (fr) |
| DE (1) | DE60118591T2 (fr) |
| ES (1) | ES2261521T3 (fr) |
| GB (1) | GB0027769D0 (fr) |
| HK (1) | HK1057171A1 (fr) |
| MX (1) | MXPA03004128A (fr) |
| PL (1) | PL201779B1 (fr) |
| RU (1) | RU2287321C2 (fr) |
| WO (1) | WO2002039960A2 (fr) |
| ZA (1) | ZA200303089B (fr) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1407760A1 (fr) * | 2002-10-08 | 2004-04-14 | Cognis France S.A. | Procédé de protection de la peau contre le vieillissement |
| EP1543834A1 (fr) * | 2003-12-16 | 2005-06-22 | Biodynamics | Production de d'extraits de houblon ayant une bioactivité oestrogénique et anti-proliférative |
| JP2005343864A (ja) * | 2004-06-07 | 2005-12-15 | Kuraray Co Ltd | 皮膚外用剤 |
| WO2006097191A1 (fr) * | 2005-03-12 | 2006-09-21 | Unilever Plc | Compositions de soins des cheveux et/ou du cuir chevelu incorporant des composes flavonoides |
| JP2008245558A (ja) * | 2007-03-29 | 2008-10-16 | Naris Cosmetics Co Ltd | 抗老化素材の評価方法及びそれを配合した化粧料の製造方法 |
| HU227970B1 (en) | 2007-07-10 | 2012-07-30 | Egis Gyogyszergyar Nyrt | Pharmaceutical compositions containing silicones of high volatility |
| JP5936841B2 (ja) * | 2011-10-05 | 2016-06-22 | 森永製菓株式会社 | ８−ジメチルアリル−（−）−エピガロカテキン−３−ｏ−ガレート |
| US11154535B2 (en) | 2012-07-31 | 2021-10-26 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
| US10045935B2 (en) | 2012-07-31 | 2018-08-14 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
| EP2735302A1 (fr) * | 2012-11-22 | 2014-05-28 | KAIROSmetics UG | Composition topique comprenant un extrait de houblon et naringénine de 8-prenyl et ses utilisations |
| DE102013017165A1 (de) | 2013-10-16 | 2015-04-16 | Eberhard Karls Universität Tübingen Medizinische Fakultät | Zusammensetzung zur Immunmodulation |
| CN104000758B (zh) * | 2014-05-27 | 2016-09-28 | 李秀玲 | 一种含中药成分的皮肤护理组合物及其制备方法 |
| WO2021089840A1 (fr) | 2019-11-08 | 2021-05-14 | Mrm Health N.V. | Procédé de fermentation pour la production de phytoestrogènes |
| JP6886539B1 (ja) * | 2020-03-12 | 2021-06-16 | 株式会社エイムソウル | 異文化適応力評価システムおよび異文化適応力評価方法 |
| JP2023536982A (ja) | 2020-08-06 | 2023-08-30 | アイリズム・テクノロジーズ・インコーポレイテッド | 生理学的モニタリング装置の電気部品 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6050765B2 (ja) * | 1975-08-07 | 1985-11-11 | 徳太郎 松井 | 皮膚化粧料 |
| JPH035423A (ja) * | 1989-06-01 | 1991-01-11 | Ichimaru Pharcos Co Ltd | フラボノイド含有過酸化脂質生成抑制剤 |
| JPH0368518A (ja) * | 1989-08-08 | 1991-03-25 | Tsumura & Co | テストステロン５α‐リダクターゼ阻害剤 |
| JP3241440B2 (ja) * | 1992-07-02 | 2001-12-25 | 有限会社野々川商事 | 化粧料 |
| JPH08165238A (ja) * | 1994-12-12 | 1996-06-25 | Sankyo Co Ltd | エストロゲン作用剤 |
| KR100253842B1 (ko) * | 1997-09-12 | 2000-07-01 | 유상옥 | 멀베린을 함유하는 미백화장료 |
| JP2000198724A (ja) * | 1998-01-28 | 2000-07-18 | Pola Chem Ind Inc | 美白用皮膚外用剤 |
| JPH11246387A (ja) * | 1998-03-03 | 1999-09-14 | Shiseido Co Ltd | 抗老化剤 |
| FR2778663B1 (fr) * | 1998-05-15 | 2001-05-18 | Coletica | Nouveaux esters de flavonoides,leur utilisation en cosmetique, dermopharmacie, en pharmacie et en agro-alimentaire |
| EP1190630A1 (fr) * | 2000-09-22 | 2002-03-27 | Unilever N.V. | Utilisation de prényle de flavones |
-
2000
- 2000-11-14 GB GBGB0027769.9A patent/GB0027769D0/en not_active Ceased
-
2001
- 2001-11-02 ES ES01996350T patent/ES2261521T3/es not_active Expired - Lifetime
- 2001-11-02 EP EP01996350A patent/EP1333805B1/fr not_active Expired - Lifetime
- 2001-11-02 PL PL362757A patent/PL201779B1/pl not_active IP Right Cessation
- 2001-11-02 BR BR0115389-7A patent/BR0115389A/pt not_active IP Right Cessation
- 2001-11-02 CN CN01818894XA patent/CN1217652C/zh not_active Expired - Fee Related
- 2001-11-02 KR KR1020037006467A patent/KR100847609B1/ko not_active IP Right Cessation
- 2001-11-02 WO PCT/EP2001/012732 patent/WO2002039960A2/fr active IP Right Grant
- 2001-11-02 JP JP2002542335A patent/JP2004513902A/ja active Pending
- 2001-11-02 AU AU2002220679A patent/AU2002220679B9/en not_active Ceased
- 2001-11-02 MX MXPA03004128A patent/MXPA03004128A/es active IP Right Grant
- 2001-11-02 CA CA002426467A patent/CA2426467C/fr not_active Expired - Fee Related
- 2001-11-02 DE DE60118591T patent/DE60118591T2/de not_active Expired - Lifetime
- 2001-11-02 AU AU2067902A patent/AU2067902A/xx active Pending
- 2001-11-02 RU RU2003117446/15A patent/RU2287321C2/ru not_active IP Right Cessation
- 2001-11-02 AT AT01996350T patent/ATE322314T1/de not_active IP Right Cessation
- 2001-11-02 CZ CZ20031335A patent/CZ299342B6/cs not_active IP Right Cessation
-
2003
- 2003-04-22 ZA ZA200303089A patent/ZA200303089B/en unknown
-
2004
- 2004-01-05 HK HK04100063A patent/HK1057171A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002039960A3 (fr) | 2002-07-25 |
| CZ20031335A3 (cs) | 2003-09-17 |
| AU2067902A (en) | 2002-05-27 |
| RU2287321C2 (ru) | 2006-11-20 |
| CA2426467C (fr) | 2010-01-05 |
| EP1333805A2 (fr) | 2003-08-13 |
| CN1217652C (zh) | 2005-09-07 |
| ATE322314T1 (de) | 2006-04-15 |
| KR20030062334A (ko) | 2003-07-23 |
| HK1057171A1 (en) | 2004-03-19 |
| EP1333805B1 (fr) | 2006-04-05 |
| AU2002220679B9 (en) | 2006-07-06 |
| CA2426467A1 (fr) | 2002-05-23 |
| PL362757A1 (en) | 2004-11-02 |
| DE60118591T2 (de) | 2006-08-24 |
| GB0027769D0 (en) | 2000-12-27 |
| JP2004513902A (ja) | 2004-05-13 |
| AU2002220679B2 (en) | 2006-05-18 |
| ES2261521T3 (es) | 2006-11-16 |
| MXPA03004128A (es) | 2003-08-19 |
| PL201779B1 (pl) | 2009-05-29 |
| BR0115389A (pt) | 2003-08-26 |
| WO2002039960A2 (fr) | 2002-05-23 |
| CN1474684A (zh) | 2004-02-11 |
| DE60118591D1 (de) | 2006-05-18 |
| KR100847609B1 (ko) | 2008-07-21 |
| CZ299342B6 (cs) | 2008-06-25 |
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