ZA200303045B - Inhalable formulation of a solution containing a tiotropium salt. - Google Patents

Inhalable formulation of a solution containing a tiotropium salt.

Info

Publication number
ZA200303045B
ZA200303045B ZA200303045A ZA200303045A ZA200303045B ZA 200303045 B ZA200303045 B ZA 200303045B ZA 200303045 A ZA200303045 A ZA 200303045A ZA 200303045 A ZA200303045 A ZA 200303045A ZA 200303045 B ZA200303045 B ZA 200303045B
Authority
ZA
South Africa
Prior art keywords
solution containing
tiotropium salt
inhalable formulation
inhalable
formulation
Prior art date
Application number
ZA200303045A
Other languages
English (en)
Inventor
Karin Drechsel
Barbara Niklaus-Humke
Christel Schmelzer
Petra Barth
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7661727&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200303045(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of ZA200303045B publication Critical patent/ZA200303045B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200303045A 2000-10-31 2003-04-17 Inhalable formulation of a solution containing a tiotropium salt. ZA200303045B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10054042 2000-10-31

Publications (1)

Publication Number Publication Date
ZA200303045B true ZA200303045B (en) 2004-04-22

Family

ID=7661727

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200303045A ZA200303045B (en) 2000-10-31 2003-04-17 Inhalable formulation of a solution containing a tiotropium salt.

Country Status (33)

Country Link
EP (1) EP1335729A2 (ja)
JP (1) JP4559703B2 (ja)
KR (1) KR100983208B1 (ja)
CN (1) CN1237970C (ja)
AR (1) AR038765A1 (ja)
AU (2) AU2002221741B2 (ja)
BG (1) BG66425B1 (ja)
BR (1) BR0115016A (ja)
CA (1) CA2427583C (ja)
CZ (1) CZ305033B6 (ja)
DE (1) DE10152369A1 (ja)
EA (1) EA009068B1 (ja)
EC (1) ECSP034570A (ja)
EE (1) EE05343B1 (ja)
HK (1) HK1060569A1 (ja)
HR (1) HRP20030337A2 (ja)
HU (1) HUP0301377A3 (ja)
IL (2) IL155676A0 (ja)
ME (1) ME00242B (ja)
MX (1) MXPA03003750A (ja)
MY (1) MY132777A (ja)
NO (1) NO332524B1 (ja)
NZ (1) NZ526024A (ja)
PE (1) PE20020518A1 (ja)
PL (1) PL361001A1 (ja)
SA (1) SA01220503B1 (ja)
SK (1) SK288031B6 (ja)
TW (1) TWI296934B (ja)
UA (1) UA76435C2 (ja)
UY (1) UY26991A1 (ja)
WO (1) WO2002036591A2 (ja)
YU (1) YU33103A (ja)
ZA (1) ZA200303045B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60114865T2 (de) 2000-04-28 2006-07-27 Kosan Biosciences, Inc., Hayward Heterologe herstellung von polyketiden
US20030235538A1 (en) 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
CA2544611A1 (en) * 2003-10-09 2005-04-21 Inverseon, Inc. Method of treating airway diseases with beta-adrenergic inverse agonists
SE0303269L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Medicinsk produkt
MX2007011273A (es) * 2005-03-16 2007-11-08 Meda Pharma Gmbh & Co Kg La combinacion de anticolinergicos y antagonistas del receptor de leucotrieno para el tratamiento de enfermedades respiratorias.
WO2007140285A2 (en) * 2006-05-26 2007-12-06 Dey, L.P. Nebulizable compositions of quaternary ammonium muscarinic receptor antagonists
CN100446770C (zh) * 2007-01-10 2008-12-31 上海现代药物制剂工程研究中心有限公司 丙酸培氯米松水雾剂
TR200907237A2 (tr) * 2009-09-23 2011-04-21 Bi̇lgi̇ç Mahmut Tiotropyum kuru toz kombinasyonu
CN116196298A (zh) * 2018-07-26 2023-06-02 四川海思科制药有限公司 一种含格隆铵盐的气雾剂药物组合物及其制备方法与应用
CN111936124A (zh) * 2018-07-26 2020-11-13 四川海思科制药有限公司 一种含格隆铵盐及茚达特罗盐的气雾剂药物组合物及其制备方法与应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0504112A3 (en) * 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
DE4203306A1 (de) * 1992-02-06 1993-08-12 Ig Spruehtechnik Gmbh Asthma oder pulmonal-aerosolzubereitungen mit lecithin
RU2223750C2 (ru) * 1995-06-27 2004-02-20 Берингер Ингельхайм КГ Лекарственная композиция в виде раствора, предназначенная для получения способного к ингаляции аэрозоля
US5824669A (en) * 1996-03-22 1998-10-20 Nitromed, Inc. Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders
AU3153797A (en) * 1996-06-04 1998-01-05 Procter & Gamble Company, The A nasal spray containing an intranasal steroid and an antihistamine
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
JPH10298107A (ja) * 1997-04-25 1998-11-10 Taisho Pharmaceut Co Ltd 医薬組成物
US6475467B1 (en) * 1998-08-04 2002-11-05 Jago Research Ag Medicinal aerosol formulations
DE19847968A1 (de) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen

Also Published As

Publication number Publication date
HUP0301377A3 (en) 2005-12-28
EE05343B1 (et) 2010-10-15
MEP40708A (en) 2011-02-10
PL361001A1 (en) 2004-09-20
HK1060569A1 (en) 2004-08-13
UY26991A1 (es) 2002-06-20
JP2004523482A (ja) 2004-08-05
NO20031914L (no) 2003-06-23
BR0115016A (pt) 2005-05-03
CN1473044A (zh) 2004-02-04
EE200300202A (et) 2003-10-15
ECSP034570A (es) 2003-06-25
AR038765A1 (es) 2005-01-26
BG66425B1 (bg) 2014-04-30
KR20040010552A (ko) 2004-01-31
SK288031B6 (sk) 2012-12-03
AU2174102A (en) 2002-05-15
HUP0301377A2 (hu) 2003-10-28
NO332524B1 (no) 2012-10-08
WO2002036591A2 (de) 2002-05-10
DE10152369A1 (de) 2002-05-08
SA01220503B1 (ar) 2007-03-10
ME00242B (me) 2011-05-10
IL155676A (en) 2012-05-31
BG107726A (bg) 2004-11-30
YU33103A (sh) 2006-05-25
JP4559703B2 (ja) 2010-10-13
PE20020518A1 (es) 2002-07-12
HRP20030337A2 (en) 2005-04-30
EA200300483A1 (ru) 2003-12-25
CZ305033B6 (cs) 2015-04-08
CA2427583A1 (en) 2002-05-10
UA76435C2 (en) 2006-08-15
IL155676A0 (en) 2003-11-23
EA009068B1 (ru) 2007-10-26
CA2427583C (en) 2008-02-12
MXPA03003750A (es) 2004-10-15
CN1237970C (zh) 2006-01-25
MY132777A (en) 2007-10-31
TWI296934B (en) 2008-05-21
NZ526024A (en) 2005-10-28
CZ20031487A3 (cs) 2003-09-17
NO20031914D0 (no) 2003-04-29
SK5262003A3 (en) 2003-10-07
EP1335729A2 (de) 2003-08-20
WO2002036591A3 (de) 2002-07-25
KR100983208B1 (ko) 2010-09-20
AU2002221741B2 (en) 2007-04-05

Similar Documents

Publication Publication Date Title
EG24139A (en) New inhalable powder containing tiotropium
EG24478A (en) New inhalable powder containing tiotropium
HK1064035A1 (en) Pharmaceutical salts of 1-phenyl-3-dimethylamino-propane compounds
HUP0301447A3 (en) Combined pharmaceutical compositions containing tiotropium and salmeterol salts
HK1049615A1 (en) Moxifloxacin formulation containing common salt
HK1078793A1 (en) Aerosol formulation for inhalation comprising a tiotropium salt
HK1129111A1 (en) Tiotropium salts, pharmaceutical formulations containing the salts and the use thereof
ZA200303045B (en) Inhalable formulation of a solution containing a tiotropium salt.
AU2002221741A1 (en) Inhalative solution formulation containing a tiotropium salt
GB0011807D0 (en) Formulation for inhalation
HK1060524A1 (en) Inhalative solution formulation containing a tiotropium salt
AU2002221738A1 (en) Inhalative solution formulation containing a tiotropium salt
AP2003002783A0 (en) Medicament containing activted antihtrombin iii
PT1567135E (pt) Formulação em pó para inalação contendo tiotrópio
EP1406592A4 (en) MEDICAL AEROSOL FORMULATION WITH PAIR SALT / ION
IL146694A (en) Use of an aqueous solution containing a biologically active complex of tellurium dioxide for manufacturing a medicament
GB0024517D0 (en) Use of medicaments
HK1091120A1 (en) Method of preparing a formulation containing a microdosed active principle
AU2002366034A1 (en) Ulcerative-colitis therapeutic agent containing iron salt as active ingredient
GB0015079D0 (en) Solution for pharmaceutical use
HU0001414D0 (en) New paroxetin salt and medicament containing it
IL175282A0 (en) Preparation of pharmaceutical salts of [1,4]-bipiperidine
PL366298A1 (en) A stable pharmaceutical formulation comprising torsemide modification ii