YU33103A - Formulacija rastvora za inhalaciju sa soli tiotropijuma - Google Patents

Formulacija rastvora za inhalaciju sa soli tiotropijuma

Info

Publication number
YU33103A
YU33103A YU33103A YUP33103A YU33103A YU 33103 A YU33103 A YU 33103A YU 33103 A YU33103 A YU 33103A YU P33103 A YUP33103 A YU P33103A YU 33103 A YU33103 A YU 33103A
Authority
YU
Yugoslavia
Prior art keywords
formulation containing
solution formulation
tiotropium salt
inhalative solution
inhalative
Prior art date
Application number
YU33103A
Other languages
English (en)
Inventor
Karin Drechsel
Barbara Niklaus-Humke
Christel Schmelzer
Petra Barth
Original Assignee
Boehringer Ingelheim Pharma Gmbh. & Co.Kg.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7661727&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU33103(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma Gmbh. & Co.Kg. filed Critical Boehringer Ingelheim Pharma Gmbh. & Co.Kg.
Priority to MEP-2008-407A priority Critical patent/ME00242B/me
Publication of YU33103A publication Critical patent/YU33103A/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Abstract

Predmetni pronalazak se odnosi na formulaciju za inhalaciju bez pogonskog gasa sa tiotropijum bromidom odn. tiotropijum bromid monohidratom koji je rastvoren u vodi ili u smeši vode i etanola i na aerosol za inhalaciju bez pogonskog gasa koji se dobija od nje.[The invention relates to a propellant-free inhalation formulation of tiotropium bromide or tiotropium bromide monohydrate, which is dissolved in water or in a mixture consisting of water and ethanol, and to propellant-free inhalable aerosols resulting therefrom.
YU33103A 2000-10-31 2001-10-24 Formulacija rastvora za inhalaciju sa soli tiotropijuma YU33103A (sh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MEP-2008-407A ME00242B (me) 2000-10-31 2001-10-24 Formulacija rastvora za inhalaciju sa soli tiotropijuma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10054042 2000-10-31

Publications (1)

Publication Number Publication Date
YU33103A true YU33103A (sh) 2006-05-25

Family

ID=7661727

Family Applications (1)

Application Number Title Priority Date Filing Date
YU33103A YU33103A (sh) 2000-10-31 2001-10-24 Formulacija rastvora za inhalaciju sa soli tiotropijuma

Country Status (33)

Country Link
EP (1) EP1335729A2 (sh)
JP (1) JP4559703B2 (sh)
KR (1) KR100983208B1 (sh)
CN (1) CN1237970C (sh)
AR (1) AR038765A1 (sh)
AU (2) AU2174102A (sh)
BG (1) BG66425B1 (sh)
BR (1) BR0115016A (sh)
CA (1) CA2427583C (sh)
CZ (1) CZ305033B6 (sh)
DE (1) DE10152369A1 (sh)
EA (1) EA009068B1 (sh)
EC (1) ECSP034570A (sh)
EE (1) EE05343B1 (sh)
HK (1) HK1060569A1 (sh)
HR (1) HRP20030337A2 (sh)
HU (1) HUP0301377A3 (sh)
IL (2) IL155676A0 (sh)
ME (1) ME00242B (sh)
MX (1) MXPA03003750A (sh)
MY (1) MY132777A (sh)
NO (1) NO332524B1 (sh)
NZ (1) NZ526024A (sh)
PE (1) PE20020518A1 (sh)
PL (1) PL361001A1 (sh)
SA (1) SA01220503B1 (sh)
SK (1) SK288031B6 (sh)
TW (1) TWI296934B (sh)
UA (1) UA76435C2 (sh)
UY (1) UY26991A1 (sh)
WO (1) WO2002036591A2 (sh)
YU (1) YU33103A (sh)
ZA (1) ZA200303045B (sh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2332727T3 (es) 2000-04-28 2010-02-11 Kosan Biosciences, Inc. Epotilona d cristalina.
US20030235538A1 (en) 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
JP2007527409A (ja) * 2003-10-09 2007-09-27 インバーセオン、インコーポレイテッド β−アドレナリンインバースアゴニストを用いて気道疾患を治療する方法
SE0303269L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Medicinsk produkt
NZ560206A (en) * 2005-03-16 2009-09-25 Meda Pharma Gmbh & Co Kg The combination of anticholinergics and leukotriene receptor antagonists for the treatment of respiratory diseases
US20070274925A1 (en) * 2006-05-26 2007-11-29 Dey, L.P. Nebulizable compositions of quaternary ammonium muscarinic receptor antagonists
CN100446770C (zh) * 2007-01-10 2008-12-31 上海现代药物制剂工程研究中心有限公司 丙酸培氯米松水雾剂
TR200907237A2 (tr) * 2009-09-23 2011-04-21 Bi̇lgi̇ç Mahmut Tiotropyum kuru toz kombinasyonu
CN111971034A (zh) * 2018-07-26 2020-11-20 四川海思科制药有限公司 一种含格隆铵盐的气雾剂药物组合物及其制备方法与应用
CN111936124A (zh) * 2018-07-26 2020-11-13 四川海思科制药有限公司 一种含格隆铵盐及茚达特罗盐的气雾剂药物组合物及其制备方法与应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0504112A3 (en) * 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
DE4203306A1 (de) * 1992-02-06 1993-08-12 Ig Spruehtechnik Gmbh Asthma oder pulmonal-aerosolzubereitungen mit lecithin
EE03509B2 (et) * 1995-06-27 2015-02-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Stabiilsed ravimikompositsioonid kandegaasita aerosoolide saamiseks
US5824669A (en) * 1996-03-22 1998-10-20 Nitromed, Inc. Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders
JPH11511758A (ja) * 1996-06-04 1999-10-12 ザ、プロクター、エンド、ギャンブル、カンパニー 鼻腔用ステロイドと抗ヒスタミン剤を含む鼻腔内噴霧薬
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
JPH10298107A (ja) * 1997-04-25 1998-11-10 Taisho Pharmaceut Co Ltd 医薬組成物
EP1102579B1 (de) * 1998-08-04 2003-03-19 Jago Research Ag Medizinische aerosolformulierungen
DE19847968A1 (de) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen

Also Published As

Publication number Publication date
KR20040010552A (ko) 2004-01-31
ME00242B (me) 2011-05-10
AU2174102A (en) 2002-05-15
JP2004523482A (ja) 2004-08-05
CZ20031487A3 (cs) 2003-09-17
CZ305033B6 (cs) 2015-04-08
NO20031914L (no) 2003-06-23
EA200300483A1 (ru) 2003-12-25
EA009068B1 (ru) 2007-10-26
CA2427583C (en) 2008-02-12
BG107726A (bg) 2004-11-30
CN1473044A (zh) 2004-02-04
KR100983208B1 (ko) 2010-09-20
EE200300202A (et) 2003-10-15
IL155676A0 (en) 2003-11-23
BR0115016A (pt) 2005-05-03
TWI296934B (en) 2008-05-21
UA76435C2 (en) 2006-08-15
WO2002036591A2 (de) 2002-05-10
CA2427583A1 (en) 2002-05-10
EP1335729A2 (de) 2003-08-20
ZA200303045B (en) 2004-04-22
NZ526024A (en) 2005-10-28
HUP0301377A2 (hu) 2003-10-28
MEP40708A (en) 2011-02-10
CN1237970C (zh) 2006-01-25
AR038765A1 (es) 2005-01-26
NO20031914D0 (no) 2003-04-29
JP4559703B2 (ja) 2010-10-13
SA01220503B1 (ar) 2007-03-10
SK288031B6 (sk) 2012-12-03
MY132777A (en) 2007-10-31
HK1060569A1 (en) 2004-08-13
HUP0301377A3 (en) 2005-12-28
NO332524B1 (no) 2012-10-08
UY26991A1 (es) 2002-06-20
PL361001A1 (en) 2004-09-20
WO2002036591A3 (de) 2002-07-25
AU2002221741B2 (en) 2007-04-05
BG66425B1 (bg) 2014-04-30
HRP20030337A2 (en) 2005-04-30
MXPA03003750A (es) 2004-10-15
ECSP034570A (es) 2003-06-25
SK5262003A3 (en) 2003-10-07
DE10152369A1 (de) 2002-05-08
PE20020518A1 (es) 2002-07-12
EE05343B1 (et) 2010-10-15
IL155676A (en) 2012-05-31

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