ZA200302157B - Bridged piperazine derivatives. - Google Patents
Bridged piperazine derivatives. Download PDFInfo
- Publication number
- ZA200302157B ZA200302157B ZA200302157A ZA200302157A ZA200302157B ZA 200302157 B ZA200302157 B ZA 200302157B ZA 200302157 A ZA200302157 A ZA 200302157A ZA 200302157 A ZA200302157 A ZA 200302157A ZA 200302157 B ZA200302157 B ZA 200302157B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- amino
- alkylamino
- alkylcarbonylamino
- alkoxy
- Prior art date
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- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title description 3
- 150000004885 piperazines Chemical class 0.000 title description 2
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- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 181
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- 125000004656 alkyl sulfonylamino group Chemical group 0.000 claims description 80
- 125000004457 alkyl amino carbonyl group Chemical group 0.000 claims description 72
- -1 hydroxy, hydroxysulfonyl Chemical group 0.000 claims description 72
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- 150000003839 salts Chemical class 0.000 claims description 46
- 125000001951 carbamoylamino group Chemical group C(N)(=O)N* 0.000 claims description 44
- 229910052739 hydrogen Inorganic materials 0.000 claims description 41
- 125000004471 alkyl aminosulfonyl group Chemical group 0.000 claims description 40
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Classifications
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| EA006447B1 (ru) | 2001-06-20 | 2005-12-29 | Пфайзер Продактс Инк. | Новые производные сульфоновых кислот |
| EE200400088A (et) | 2001-10-22 | 2004-10-15 | Pfizer Products Inc. | CCR1 retseptori suhtes antagonistlikku aktiivsustomavad piperasiiniderivaadid |
| US20050256130A1 (en) * | 2002-06-12 | 2005-11-17 | Chemocentryx, Inc. | Substituted piperazines |
| DE60328690D1 (de) | 2002-06-12 | 2009-09-17 | Chemocentryx Inc | 1-aryl-4-substituierte piperazin-derivate zur verwendung als ccr1-antagonisten zur behandlung von entzündungen und immunerkrankungen |
| US7842693B2 (en) * | 2002-06-12 | 2010-11-30 | Chemocentryx, Inc. | Substituted piperazines |
| US7589199B2 (en) * | 2002-06-12 | 2009-09-15 | Chemocentryx, Inc. | Substituted piperazines |
| US7435831B2 (en) * | 2004-03-03 | 2008-10-14 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
| CN1950082B (zh) * | 2004-03-03 | 2013-02-06 | 凯莫森特里克斯股份有限公司 | 双环和桥连的含氮杂环化物 |
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| CN101874798B (zh) * | 2010-06-29 | 2012-08-29 | 北京大学 | 白三烯a4水解酶与环氧合酶的双功能抑制剂及其用途 |
| CN105294700B (zh) * | 2014-07-01 | 2019-01-08 | 上海合全药业股份有限公司 | 一种2-氧代-3,8-二氮杂二环[3.2.1]辛烷-8-羧酸叔丁酯的制备方法 |
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| WO2020243423A1 (en) | 2019-05-31 | 2020-12-03 | Ikena Oncology, Inc. | Tead inhibitors and uses thereof |
| TW202108571A (zh) | 2019-05-31 | 2021-03-01 | 美商醫肯納腫瘤學公司 | Tead抑制劑及其用途 |
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2003
- 2003-03-17 IS IS6747A patent/IS6747A/is unknown
- 2003-03-18 ZA ZA200302157A patent/ZA200302157B/en unknown
- 2003-03-20 BG BG107655A patent/BG107655A/bg unknown
- 2003-04-08 MA MA27098A patent/MA26953A1/fr unknown
- 2003-04-08 NO NO20031572A patent/NO20031572L/no unknown
- 2003-04-15 HR HR20030298A patent/HRP20030298A2/hr not_active Application Discontinuation
- 2003-04-16 EC EC2003004561A patent/ECSP034561A/es unknown
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