ZA200210303B - Compounds for treating impaired fundic relaxation. - Google Patents
Compounds for treating impaired fundic relaxation. Download PDFInfo
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- ZA200210303B ZA200210303B ZA200210303A ZA200210303A ZA200210303B ZA 200210303 B ZA200210303 B ZA 200210303B ZA 200210303 A ZA200210303 A ZA 200210303A ZA 200210303 A ZA200210303 A ZA 200210303A ZA 200210303 B ZA200210303 B ZA 200210303B
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- South Africa
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- mol
- compound
- evaporated
- 4alkyl
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- BCNZYOJHNLTNEZ-UHFFFAOYSA-N tert-butyldimethylsilyl chloride Chemical compound CC(C)(C)[Si](C)(C)Cl BCNZYOJHNLTNEZ-UHFFFAOYSA-N 0.000 description 1
- FPGGTKZVZWFYPV-UHFFFAOYSA-M tetrabutylammonium fluoride Chemical compound [F-].CCCC[N+](CCCC)(CCCC)CCCC FPGGTKZVZWFYPV-UHFFFAOYSA-M 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 125000005951 trifluoromethanesulfonyloxy group Chemical group 0.000 description 1
- MDDPTCUZZASZIQ-UHFFFAOYSA-N tris[(2-methylpropan-2-yl)oxy]alumane Chemical compound [Al+3].CC(C)(C)[O-].CC(C)(C)[O-].CC(C)(C)[O-] MDDPTCUZZASZIQ-UHFFFAOYSA-N 0.000 description 1
- 229930195735 unsaturated hydrocarbon Natural products 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
- 230000024883 vasodilation Effects 0.000 description 1
- 235000012431 wafers Nutrition 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00202180 | 2000-06-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200210303B true ZA200210303B (en) | 2004-03-19 |
Family
ID=8171674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200210303A ZA200210303B (en) | 2000-06-22 | 2002-12-19 | Compounds for treating impaired fundic relaxation. |
Country Status (34)
| Country | Link |
|---|---|
| US (2) | US7081453B2 (ko) |
| EP (1) | EP1296987B1 (ko) |
| JP (1) | JP4911860B2 (ko) |
| KR (1) | KR100821107B1 (ko) |
| CN (2) | CN1288157C (ko) |
| AR (1) | AR032158A1 (ko) |
| AT (1) | ATE312104T1 (ko) |
| AU (1) | AU783292B2 (ko) |
| BG (1) | BG65895B1 (ko) |
| BR (1) | BR0111859B1 (ko) |
| CA (1) | CA2410233C (ko) |
| CZ (1) | CZ305005B6 (ko) |
| DE (1) | DE60115647T2 (ko) |
| EA (1) | EA005760B1 (ko) |
| EE (1) | EE04878B1 (ko) |
| EG (1) | EG24462A (ko) |
| ES (1) | ES2254467T3 (ko) |
| HK (1) | HK1057896A1 (ko) |
| HR (1) | HRP20020988B1 (ko) |
| HU (1) | HU227398B1 (ko) |
| IL (2) | IL153559A0 (ko) |
| IS (1) | IS2618B (ko) |
| JO (1) | JO2352B1 (ko) |
| MX (1) | MXPA02012844A (ko) |
| MY (1) | MY155267A (ko) |
| NO (1) | NO328547B1 (ko) |
| NZ (1) | NZ522519A (ko) |
| PA (1) | PA8519601A1 (ko) |
| PL (1) | PL201656B1 (ko) |
| SA (1) | SA01220442B1 (ko) |
| SK (1) | SK287730B6 (ko) |
| UA (1) | UA74576C2 (ko) |
| WO (1) | WO2001098306A1 (ko) |
| ZA (1) | ZA200210303B (ko) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100699512B1 (ko) | 1999-06-02 | 2007-03-26 | 얀센 파마슈티카 엔.브이. | 아미노알킬 치환된 (벤조디옥산, 벤조푸란 또는 벤조피란)유도체 |
| CA2374905C (en) | 1999-06-02 | 2010-02-23 | Janssen Pharmaceutica N.V. | Pyrrolidinyl, piperidinyl or homopiperidinyl-substituted benzopyran derivatives for treating impaired fundic relaxation |
| JO2352B1 (en) * | 2000-06-22 | 2006-12-12 | جانسين فارماسيوتيكا ان. في | Compounds for the treatment of non-adaptation of the bottom of the uterus |
| JO2654B1 (en) | 2000-09-04 | 2012-06-17 | شركة جانسين فارماسوتيكا ان. في | Multiple aryl caroxa amides are useful as lipid - lowering agents |
| JO2409B1 (en) | 2000-11-21 | 2007-06-17 | شركة جانسين فارماسوتيكا ان. في | Second-phenyl carboxy amides are useful as lipid-lowering agents |
| PT1622569E (pt) | 2003-04-24 | 2016-03-03 | Incyte Corp | Derivados de aza espiro alcanos como inibidores de metaloproteases |
| JP4896476B2 (ja) * | 2005-09-16 | 2012-03-14 | 広栄化学工業株式会社 | メチルオキシメチルアミノピリジン誘導体及びその製造方法 |
| US7999107B2 (en) | 2007-01-31 | 2011-08-16 | Merck Sharp & Dohme Corp. | Substituted pyrano[2,3-B]pyridine derivatives as cannabinoid-1 receptor modulators |
| JP2010526825A (ja) * | 2007-05-10 | 2010-08-05 | エーエムアール テクノロジー インコーポレイテッド | アリール置換およびヘテロアリール置換テトラヒドロベンゾ−１，４−ジアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用 |
| GEP201706656B (en) | 2011-11-11 | 2017-04-25 | Pfizer | 2-thiopyrimidinones |
| WO2016178113A1 (en) | 2015-05-05 | 2016-11-10 | Pfizer Inc. | 2-thiopyrimidinones |
| CN105481839B (zh) * | 2015-11-23 | 2018-05-11 | 安徽千和新材料科技发展有限公司 | 一种光活性环氧啉对映体的制备方法 |
| EP3229193A1 (en) | 2016-04-07 | 2017-10-11 | The Boeing Company | A computer-implemented method and system for sharing information between passengers and air traffic management stakeholders |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3910930A (en) | 1973-01-04 | 1975-10-07 | Janssen Pharmaceutica Nv | 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones |
| DE2400049A1 (de) * | 1974-01-02 | 1975-07-10 | Spumalit Anstalt | Transportkasten aus kunststoff, insbesondere fuer flaschen |
| GR71865B (ko) | 1978-03-20 | 1983-07-07 | Ciba Geigy | |
| US4329348A (en) * | 1979-02-26 | 1982-05-11 | Ciba-Geigy Corporation | N-Oxacyclic-alkylpiperidines as psychostimulants |
| EP0144101B1 (en) * | 1983-11-30 | 1991-02-06 | Janssen Pharmaceutica N.V. | Bicyclic heterocyclyl containing n-(bicyclic heterocyclyl)-4-piperidinamines |
| SI9300097B (en) * | 1992-02-27 | 2001-12-31 | Janssen Pharmaceutica Nv | (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines |
| ZA931343B (en) | 1992-03-06 | 1993-09-24 | Akzo Nv | 1,4-dioxino(2,3-b)pyridine derivatives. |
| US6403103B1 (en) * | 1994-08-12 | 2002-06-11 | Bio Merieux | Trypanosoma cruzi antigen, gene encoding therefore, and methods of detecting and treating chagas disease |
| FR2744451B1 (fr) * | 1996-02-01 | 1998-04-24 | Pf Medicament | Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique |
| US6133277A (en) * | 1997-12-05 | 2000-10-17 | Janssen Pharmaceutica N.V. | (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties |
| KR100699512B1 (ko) * | 1999-06-02 | 2007-03-26 | 얀센 파마슈티카 엔.브이. | 아미노알킬 치환된 (벤조디옥산, 벤조푸란 또는 벤조피란)유도체 |
| CA2374905C (en) * | 1999-06-02 | 2010-02-23 | Janssen Pharmaceutica N.V. | Pyrrolidinyl, piperidinyl or homopiperidinyl-substituted benzopyran derivatives for treating impaired fundic relaxation |
| TWI225488B (en) * | 1999-12-21 | 2004-12-21 | Janssen Pharmaceutica Nv | Derivatives of homopiperidinyl substituted benzimidazole analogues |
| JO2352B1 (en) * | 2000-06-22 | 2006-12-12 | جانسين فارماسيوتيكا ان. في | Compounds for the treatment of non-adaptation of the bottom of the uterus |
-
2001
- 2001-05-29 JO JO200184A patent/JO2352B1/en active
- 2001-06-13 MX MXPA02012844A patent/MXPA02012844A/es active IP Right Grant
- 2001-06-13 ES ES01962742T patent/ES2254467T3/es not_active Expired - Lifetime
- 2001-06-13 CZ CZ2003-115A patent/CZ305005B6/cs not_active IP Right Cessation
- 2001-06-13 KR KR1020027014679A patent/KR100821107B1/ko not_active IP Right Cessation
- 2001-06-13 US US10/311,612 patent/US7081453B2/en not_active Expired - Lifetime
- 2001-06-13 AU AU83864/01A patent/AU783292B2/en not_active Ceased
- 2001-06-13 AT AT01962742T patent/ATE312104T1/de not_active IP Right Cessation
- 2001-06-13 UA UA20021210045A patent/UA74576C2/uk unknown
- 2001-06-13 DE DE60115647T patent/DE60115647T2/de not_active Expired - Lifetime
- 2001-06-13 EA EA200300049A patent/EA005760B1/ru not_active IP Right Cessation
- 2001-06-13 EP EP01962742A patent/EP1296987B1/en not_active Expired - Lifetime
- 2001-06-13 WO PCT/EP2001/006749 patent/WO2001098306A1/en active IP Right Grant
- 2001-06-13 BR BRPI0111859-5A patent/BR0111859B1/pt not_active IP Right Cessation
- 2001-06-13 SK SK49-2003A patent/SK287730B6/sk not_active IP Right Cessation
- 2001-06-13 CN CNB018116108A patent/CN1288157C/zh not_active Expired - Fee Related
- 2001-06-13 EE EEP200200694A patent/EE04878B1/xx not_active IP Right Cessation
- 2001-06-13 JP JP2002504262A patent/JP4911860B2/ja not_active Expired - Fee Related
- 2001-06-13 HU HU0301185A patent/HU227398B1/hu not_active IP Right Cessation
- 2001-06-13 NZ NZ522519A patent/NZ522519A/en not_active IP Right Cessation
- 2001-06-13 IL IL15355901A patent/IL153559A0/xx active IP Right Grant
- 2001-06-13 PL PL358886A patent/PL201656B1/pl unknown
- 2001-06-13 CA CA2410233A patent/CA2410233C/en not_active Expired - Fee Related
- 2001-06-13 CN CNB200510113576XA patent/CN100516066C/zh not_active Expired - Fee Related
- 2001-06-14 PA PA20018519601A patent/PA8519601A1/es unknown
- 2001-06-20 EG EG20010661A patent/EG24462A/xx active
- 2001-06-20 MY MYPI20012913A patent/MY155267A/en unknown
- 2001-06-21 AR ARP010102955A patent/AR032158A1/es active IP Right Grant
- 2001-10-10 SA SA1220442A patent/SA01220442B1/ar unknown
-
2002
- 2002-10-25 IS IS6591A patent/IS2618B/is unknown
- 2002-11-25 BG BG107313A patent/BG65895B1/bg unknown
- 2002-12-12 HR HR20020988A patent/HRP20020988B1/xx not_active IP Right Cessation
- 2002-12-19 ZA ZA200210303A patent/ZA200210303B/en unknown
- 2002-12-19 IL IL153559A patent/IL153559A/en not_active IP Right Cessation
- 2002-12-23 NO NO20026219A patent/NO328547B1/no not_active IP Right Cessation
-
2004
- 2004-02-04 HK HK04100726A patent/HK1057896A1/xx not_active IP Right Cessation
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2006
- 2006-02-16 US US11/355,402 patent/US7423048B2/en not_active Expired - Fee Related
Also Published As
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