ZA200209664B - IL-8 Receptor Antagonists. - Google Patents
IL-8 Receptor Antagonists. Download PDFInfo
- Publication number
- ZA200209664B ZA200209664B ZA200209664A ZA200209664A ZA200209664B ZA 200209664 B ZA200209664 B ZA 200209664B ZA 200209664 A ZA200209664 A ZA 200209664A ZA 200209664 A ZA200209664 A ZA 200209664A ZA 200209664 B ZA200209664 B ZA 200209664B
- Authority
- ZA
- South Africa
- Prior art keywords
- dione
- cyclobut
- ene
- hydroxy
- phenylamino
- Prior art date
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- 229940044551 receptor antagonist Drugs 0.000 title description 2
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US7829085B2 (en) | 1999-07-14 | 2010-11-09 | Life Sciences Research Partners Vzw | Methods of treating hemostasis disorders using antibodies binding the C1 domain of factor VIII |
WO2005016455A2 (en) | 2003-08-14 | 2005-02-24 | D. Collen Research Foundation Vzw | Antibodies against factor viii with modified glycosylation in the variable region |
DE60230722D1 (de) * | 2001-01-16 | 2009-02-26 | Smithkline Beecham Corp | Il-8-rezeptor-antagonisten |
ATE346043T1 (de) * | 2001-01-16 | 2006-12-15 | Smithkline Beecham Corp | Il-8-rezeptorantagonisten |
AU2002303084B2 (en) * | 2001-02-02 | 2006-05-25 | Pharmacopiea, Inc. | 3,4-di-substituted cyclobutene-1, 2 -diones as CXC chemokine receptor antagonists |
US20040106794A1 (en) | 2001-04-16 | 2004-06-03 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
DK1818325T3 (da) * | 2001-04-16 | 2010-05-31 | Schering Corp | 3,4-di-substituerede cyklobuten-1,2-dioner som CXC-chemokin receptorligander |
US7132445B2 (en) | 2001-04-16 | 2006-11-07 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
MXPA04003439A (es) | 2001-10-12 | 2004-07-08 | Schering Corp | Compuestos de maleimida 3,4 disustituidos como antagonistas de receptor de quimiocina cxc. |
US6878709B2 (en) | 2002-01-04 | 2005-04-12 | Schering Corporation | 3,4-di-substituted pyridazinediones as CXC chemokine receptor antagonists |
MXPA04009127A (es) | 2002-03-18 | 2005-01-25 | Schering Corp | Tratamiento de enfermedades mediadas por quimiocinas. |
AR040734A1 (es) * | 2002-07-30 | 2005-04-20 | Pharmacopeia Drug Discovery | Ciclobuten 1,2- dionas 3, 4- di -sustituidas como ligandos del receptor de quimiocina cxc |
AU2003288922A1 (en) | 2002-10-09 | 2004-05-04 | Pharmacopeia, Inc. | Thiadiazoledioxides and thiadiazoleoxides as cxc- and cc-chemokine receptor ligands |
TW200418812A (en) * | 2002-10-29 | 2004-10-01 | Smithkline Beecham Corp | IL-8 receptor antagonists |
US20050026948A1 (en) * | 2003-07-29 | 2005-02-03 | Boehringer Ingelheim International Gmbh | Medicaments for inhalation comprising an anticholinergic and a betamimetic |
MXPA06007076A (es) | 2003-12-19 | 2006-08-31 | Pharmacopeia Drug Discovery | Tiadiazoles como ligandos del receptor cxc y cc-quimiocina. |
US7671212B2 (en) | 2003-12-22 | 2010-03-02 | Schering Corporation | Isothiazole dioxides as CXC- and CC-chemokine receptor ligands |
US20070249625A1 (en) * | 2004-10-20 | 2007-10-25 | Jakob Busch-Petersen | Il-8 Receptor Antagonists |
CA2613607A1 (en) | 2005-06-29 | 2007-01-04 | Schering Corporation | Di-substituted oxadiazoles as cxc-chemokine receptor ligands |
DE602006017849D1 (de) | 2005-06-29 | 2010-12-09 | Schering Corp | 5,6-disubstituierte oxadiazolopyrazine und thiadiazolopyrazine als liganden des cxc-chemokinrezeptors |
WO2007124423A2 (en) * | 2006-04-21 | 2007-11-01 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
BRPI0710232B8 (pt) * | 2006-04-21 | 2021-05-25 | Glaxosmithkline Llc | composto antagonista do receptor de il-8, composição farmacêutica que compreende o dito composto e uso do mesmo para o tratamento de uma doença mediada por quimiocina |
AR061571A1 (es) * | 2006-06-23 | 2008-09-03 | Smithkline Beecham Corp | Compuesto sal del acido toluenosulfonico de 4-{[6-cloro-3-({[(2- cloro-3-fluorofenil) amino]carbonil} amino)- 2- hidroxifenil]sulfonil] -1- piperazinacarbxilato de 1.1-dimetiletilo, composicion farmaceutica que lo comprende su uso para la fabricacion de un medicamento combinacion farmaceutica con un |
US20090041753A1 (en) * | 2006-09-26 | 2009-02-12 | Miller Robert H | Cytokine signaling |
WO2015027160A2 (en) * | 2013-08-22 | 2015-02-26 | Northeastern University | Allosteric modulators of the cannibinoid 1 receptor |
TWI724056B (zh) | 2015-11-19 | 2021-04-11 | 美商卡默森屈有限公司 | Cxcr2抑制劑 |
TWI734715B (zh) | 2015-11-19 | 2021-08-01 | 美商卡默森屈有限公司 | 趨化因子受體調節劑 |
JP2020530848A (ja) | 2017-08-14 | 2020-10-29 | アラーガン、インコーポレイテッドAllergan,Incorporated | 3,4−二置換3−シクロブテン−1,2−ジオンおよびその使用 |
AU2019205786B2 (en) | 2018-01-08 | 2023-12-14 | Chemocentryx, Inc. | Methods of treating generalized pustular psoriasis with an antagonist of CCR6 or CXCR2 |
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JPH11503110A (ja) * | 1995-02-17 | 1999-03-23 | スミスクライン・ビーチャム・コーポレイション | Il−8受容体拮抗剤 |
AR033803A1 (es) * | 2000-03-01 | 2004-01-07 | Smithkline Beecham Corp | Compuestos de dianilino escuarano, composiciones farmaceuticas que los comprenden, y el uso de los mismos en la fabricacion de medicamentos para tratar enfermedades mediadas por quimioquinas |
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WO2001092202A1 (en) | 2001-12-06 |
US7008962B2 (en) | 2006-03-07 |
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NO20025754L (no) | 2002-11-29 |
CN1454204A (zh) | 2003-11-05 |
NO20025754D0 (no) | 2002-11-29 |
KR20030017526A (ko) | 2003-03-03 |
CZ20023915A3 (cs) | 2003-04-16 |
AU2001266640A1 (en) | 2001-12-11 |
HUP0302382A3 (en) | 2004-09-28 |
HUP0302382A2 (hu) | 2003-12-29 |
PL366230A1 (en) | 2005-01-24 |
CA2411323A1 (en) | 2001-12-06 |
EP1284956A1 (en) | 2003-02-26 |
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