ZA200208628B - Inhibition of angiogenesis and tumor growth. - Google Patents

Inhibition of angiogenesis and tumor growth. Download PDF

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Publication number
ZA200208628B
ZA200208628B ZA200208628A ZA200208628A ZA200208628B ZA 200208628 B ZA200208628 B ZA 200208628B ZA 200208628 A ZA200208628 A ZA 200208628A ZA 200208628 A ZA200208628 A ZA 200208628A ZA 200208628 B ZA200208628 B ZA 200208628B
Authority
ZA
South Africa
Prior art keywords
compound
substance
composition
covalent bond
cis
Prior art date
Application number
ZA200208628A
Other languages
English (en)
Inventor
Deale L Boger
David A Cheresh
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of ZA200208628B publication Critical patent/ZA200208628B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
ZA200208628A 2000-03-27 2002-10-24 Inhibition of angiogenesis and tumor growth. ZA200208628B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19226000P 2000-03-27 2000-03-27

Publications (1)

Publication Number Publication Date
ZA200208628B true ZA200208628B (en) 2004-02-12

Family

ID=22708924

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA200208628A ZA200208628B (en) 2000-03-27 2002-10-24 Inhibition of angiogenesis and tumor growth.
ZA200208626A ZA200208626B (en) 2000-03-27 2002-10-24 Methods for inhibiting angiogenesis and tumor growth.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA200208626A ZA200208626B (en) 2000-03-27 2002-10-24 Methods for inhibiting angiogenesis and tumor growth.

Country Status (15)

Country Link
EP (2) EP1272173A4 (fr)
JP (2) JP2003528850A (fr)
KR (2) KR100767616B1 (fr)
CN (2) CN1229339C (fr)
AU (4) AU5101801A (fr)
CA (3) CA2659030A1 (fr)
CZ (2) CZ20023510A3 (fr)
HU (2) HUP0301621A3 (fr)
MX (2) MXPA02009510A (fr)
NO (2) NO328969B1 (fr)
PL (2) PL358272A1 (fr)
RU (2) RU2276133C2 (fr)
SK (2) SK14852002A3 (fr)
WO (2) WO2001072699A1 (fr)
ZA (2) ZA200208628B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2315721T5 (es) 2003-10-23 2012-08-24 Otsuka Pharmaceutical Co., Ltd. Formulación de aripiprazol inyectable estéril de liberación controlada y procedimiento
UA97286C2 (ru) 2007-07-31 2012-01-25 Оцука Фармасьютикал Ко., Лтд. Способ изготовления суспензии арипипразола и лиофилизированного состава

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8311286D0 (en) * 1983-04-26 1983-06-02 Searle & Co Carboxyalkyl peptide derivatives
JPH05125029A (ja) 1991-11-06 1993-05-21 Yamanouchi Pharmaceut Co Ltd 新規なアミド化合物又はその塩
GB9308695D0 (en) * 1993-04-27 1993-06-09 Celltech Ltd Peptidyl derivatives
GB9405076D0 (en) * 1994-03-16 1994-04-27 Inst Of Ophtalmology A medical use of matrix metalloproteinase inhibitors
AUPO104496A0 (en) * 1996-07-17 1996-08-08 Biomolecular Research Institute Limited Angiogenic inhibitory compounds
KR20000068415A (ko) * 1996-09-04 2000-11-25 로즈 암스트롱, 크리스틴 에이. 트러트웨인 매트릭스 메탈로프로테이나제 억제용 화합물 및 방법
EP0968423A4 (fr) * 1997-02-07 2002-10-30 Scripps Research Inst Synthese convergente de banque combinatoire
KR100596109B1 (ko) * 1998-03-27 2006-07-05 제넨테크, 인크. Cd11/cd18 부착 수용체 매개 질환 치료용 길항제

Also Published As

Publication number Publication date
CA2403630C (fr) 2009-05-26
JP2003528850A (ja) 2003-09-30
RU2276133C2 (ru) 2006-05-10
CA2659030A1 (fr) 2001-10-04
EP1272173A4 (fr) 2006-05-03
CN1245967C (zh) 2006-03-22
EP1272173A1 (fr) 2003-01-08
AU2001251018B2 (en) 2005-12-01
WO2001072699A1 (fr) 2001-10-04
MXPA02009504A (es) 2003-05-21
AU4949901A (en) 2001-10-08
CZ20023510A3 (cs) 2003-03-12
KR20020091156A (ko) 2002-12-05
KR20020084258A (ko) 2002-11-04
AU2001249499B2 (en) 2005-04-21
CA2403630A1 (fr) 2001-10-04
AU5101801A (en) 2001-10-08
NO20024578L (no) 2002-11-20
CZ20023509A3 (cs) 2003-06-18
SK14852002A3 (sk) 2003-06-03
CA2403871C (fr) 2010-05-11
HUP0301797A3 (en) 2010-09-28
ZA200208626B (en) 2004-02-16
NO20024576L (no) 2002-11-20
CA2403871A1 (fr) 2001-10-04
CN1229339C (zh) 2005-11-30
PL358272A1 (en) 2004-08-09
RU2269339C2 (ru) 2006-02-10
CN1429106A (zh) 2003-07-09
CN1441777A (zh) 2003-09-10
PL366316A1 (en) 2005-01-24
KR100767616B1 (ko) 2007-10-18
NO328969B1 (no) 2010-06-28
SK14842002A3 (sk) 2003-04-01
KR100776185B1 (ko) 2007-11-16
JP2003528140A (ja) 2003-09-24
HUP0301621A2 (hu) 2003-09-29
NO20024576D0 (no) 2002-09-24
NO20024578D0 (no) 2002-09-24
WO2001072297A1 (fr) 2001-10-04
EP1276713A1 (fr) 2003-01-22
HUP0301621A3 (en) 2009-06-29
RU2002128751A (ru) 2004-03-10
HUP0301797A2 (hu) 2003-09-29
EP1276713A4 (fr) 2006-05-03
PL205134B1 (pl) 2010-03-31
MXPA02009510A (es) 2003-05-21

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