ZA200204969B - Novel indole derivatives. - Google Patents

Novel indole derivatives. Download PDF

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Publication number
ZA200204969B
ZA200204969B ZA200204969A ZA200204969A ZA200204969B ZA 200204969 B ZA200204969 B ZA 200204969B ZA 200204969 A ZA200204969 A ZA 200204969A ZA 200204969 A ZA200204969 A ZA 200204969A ZA 200204969 B ZA200204969 B ZA 200204969B
Authority
ZA
South Africa
Prior art keywords
piperazin
indole
phenylsulfanyl
phenoxy
propyl
Prior art date
Application number
ZA200204969A
Other languages
English (en)
Inventor
Thomas Ruhland
Christian Krog-Jensen
Mario Rottlaender
Gitte Mikkelsen
Kim Andersen
Ejner Knud Moltzen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of ZA200204969B publication Critical patent/ZA200204969B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200204969A 1999-12-30 2002-06-20 Novel indole derivatives. ZA200204969B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA199901889 1999-12-30

Publications (1)

Publication Number Publication Date
ZA200204969B true ZA200204969B (en) 2003-09-22

Family

ID=8108836

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200204969A ZA200204969B (en) 1999-12-30 2002-06-20 Novel indole derivatives.

Country Status (23)

Country Link
US (1) US20030050307A1 (cs)
EP (1) EP1246818A1 (cs)
JP (1) JP2003519226A (cs)
KR (1) KR20020063288A (cs)
CN (1) CN1437598A (cs)
AR (1) AR027134A1 (cs)
AU (1) AU2352101A (cs)
BG (1) BG106937A (cs)
BR (1) BR0016955A (cs)
CA (1) CA2395606A1 (cs)
CZ (1) CZ20022489A3 (cs)
EA (1) EA200200727A1 (cs)
HU (1) HUP0203767A3 (cs)
IL (1) IL150336A0 (cs)
IS (1) IS6434A (cs)
MX (1) MXPA02006498A (cs)
NO (1) NO20023148D0 (cs)
NZ (1) NZ519648A (cs)
PL (1) PL355538A1 (cs)
SK (1) SK9452002A3 (cs)
TR (1) TR200201689T2 (cs)
WO (1) WO2001049680A1 (cs)
ZA (1) ZA200204969B (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002048105A2 (en) 2000-11-16 2002-06-20 Wyeth Aryloxy piperidinyl derivatives for the treatment of depression
US6656950B2 (en) * 2001-04-25 2003-12-02 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino[2,3-b]pyridine
HUP0400834A2 (hu) * 2001-06-29 2004-08-30 H. Lundbeck A/S Új indolszármazékok és ezeket tartalmazó gyógyszerkészítmények
WO2004017973A1 (ja) 2002-08-22 2004-03-04 Sumitomo Pharmaceuticals Company, Limited 統合失調症治療剤
US20060142276A1 (en) 2003-06-23 2006-06-29 Yukihiro Ohno Therapeutic agent for senile dementia
EP2357474A1 (en) 2004-02-20 2011-08-17 Dainippon Sumitomo Pharma Co., Ltd. Lurasidone for use in the treatment of memory or learning dysfunction by schizophrenia
AR055203A1 (es) * 2005-08-31 2007-08-08 Otsuka Pharma Co Ltd Derivados de benzotiofeno con propiedades antipsicoticas
JP4785881B2 (ja) * 2007-02-27 2011-10-05 大塚製薬株式会社 医薬
US8258139B2 (en) 2010-11-08 2012-09-04 Dainippon Sumitomo Pharma Co., Ltd. Method of treatment for mental disorders
PL395469A1 (pl) 2011-06-29 2013-01-07 Adamed Spólka Z Ograniczona Odpowiedzialnoscia Pochodne indoloamin do leczenia chorób osrodkowego ukladu nerwowego
CN116554145B (zh) * 2022-01-29 2025-06-03 江苏恩华药业股份有限公司 芳烷基-4-(1h)吲哚基哌嗪衍生物、其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2567884B1 (fr) * 1984-07-19 1987-03-06 Roussel Uclaf Nouveaux derives de l'indole, leur preparation, leur application comme medicaments et les compositions les renfermant
GB8830312D0 (en) * 1988-12-28 1989-02-22 Lundbeck & Co As H Heterocyclic compounds
DK148392D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Heterocykliske forbindelser
EP0900792B1 (en) * 1997-09-02 2003-10-29 Duphar International Research B.V Piperazine and piperidine derivatives as 5-HT1A and dopamine D2-receptor (ant)agonists
WO1999055672A2 (en) * 1998-04-29 1999-11-04 American Home Products Corporation Antipsychotic indolyl derivatives

Also Published As

Publication number Publication date
JP2003519226A (ja) 2003-06-17
WO2001049680A1 (en) 2001-07-12
CN1437598A (zh) 2003-08-20
BG106937A (en) 2003-04-30
NO20023148L (no) 2002-06-28
KR20020063288A (ko) 2002-08-01
EP1246818A1 (en) 2002-10-09
TR200201689T2 (tr) 2002-10-21
MXPA02006498A (es) 2002-11-29
CA2395606A1 (en) 2001-07-12
US20030050307A1 (en) 2003-03-13
IS6434A (is) 2002-06-19
AU2352101A (en) 2001-07-16
AR027134A1 (es) 2003-03-12
SK9452002A3 (en) 2002-11-06
CZ20022489A3 (cs) 2002-10-16
HUP0203767A3 (en) 2004-06-28
PL355538A1 (en) 2004-05-04
IL150336A0 (en) 2002-12-01
NZ519648A (en) 2004-05-28
HUP0203767A2 (hu) 2003-03-28
NO20023148D0 (no) 2002-06-28
EA200200727A1 (ru) 2002-12-26
BR0016955A (pt) 2003-04-29

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