TR200201689T2 - Yeni indol türevleri - Google Patents

Yeni indol türevleri

Info

Publication number
TR200201689T2
TR200201689T2 TR2002/01689T TR200201689T TR200201689T2 TR 200201689 T2 TR200201689 T2 TR 200201689T2 TR 2002/01689 T TR2002/01689 T TR 2002/01689T TR 200201689 T TR200201689 T TR 200201689T TR 200201689 T2 TR200201689 T2 TR 200201689T2
Authority
TR
Turkey
Prior art keywords
indole derivatives
new indole
formula
new
compounds
Prior art date
Application number
TR2002/01689T
Other languages
English (en)
Inventor
Ruhland Thomas
Krog-Jensen Christian
Rottlnder Mario
Mikkelsen Gitte
Andersen Kim
Knud Moltzen Ejner
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of TR200201689T2 publication Critical patent/TR200201689T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Bulus formül (I) bilesimleri saglar ki burada X O ya da S'yi temsil eder; n 2, 3, 4, 5, 6, 7, 8, 9 ya da 10'dur; m 2 ya da 3'tür; Y N, C ya da CH'i temsil eder; ve kesik çizgi istege bagli bir bagi temsil eder; R , R ', R , R , R4, R5, R6, R7, R8, R9, R10, R ve R tarifnamede belirtikleri gibidirler. Bilesimler 5-HTla-reseptörünün ligandlaridir. Formül (I)
TR2002/01689T 1999-12-30 2000-12-29 Yeni indol türevleri TR200201689T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA199901889 1999-12-30

Publications (1)

Publication Number Publication Date
TR200201689T2 true TR200201689T2 (tr) 2002-10-21

Family

ID=8108836

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/01689T TR200201689T2 (tr) 1999-12-30 2000-12-29 Yeni indol türevleri

Country Status (23)

Country Link
US (1) US20030050307A1 (tr)
EP (1) EP1246818A1 (tr)
JP (1) JP2003519226A (tr)
KR (1) KR20020063288A (tr)
CN (1) CN1437598A (tr)
AR (1) AR027134A1 (tr)
AU (1) AU2352101A (tr)
BG (1) BG106937A (tr)
BR (1) BR0016955A (tr)
CA (1) CA2395606A1 (tr)
CZ (1) CZ20022489A3 (tr)
EA (1) EA200200727A1 (tr)
HU (1) HUP0203767A3 (tr)
IL (1) IL150336A0 (tr)
IS (1) IS6434A (tr)
MX (1) MXPA02006498A (tr)
NO (1) NO20023148L (tr)
NZ (1) NZ519648A (tr)
PL (1) PL355538A1 (tr)
SK (1) SK9452002A3 (tr)
TR (1) TR200201689T2 (tr)
WO (1) WO2001049680A1 (tr)
ZA (1) ZA200204969B (tr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002048105A2 (en) 2000-11-16 2002-06-20 Wyeth Aryloxy piperidinyl derivatives for the treatment of depression
US6656950B2 (en) 2001-04-25 2003-12-02 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino[2,3-b]pyridine
JP2004535448A (ja) * 2001-06-29 2004-11-25 ハー・ルンドベック・アクチエゼルスカベット 新規インドール誘導体
EP2295061A1 (en) 2002-08-22 2011-03-16 Dainippon Sumitomo Pharma Co., Ltd. Agent for treatment of schizophrenia
WO2004113333A1 (ja) * 2003-06-23 2004-12-29 Dainippon Sumitomo Pharma Co., Ltd. 老人性痴呆症治療剤
EP2357474A1 (en) 2004-02-20 2011-08-17 Dainippon Sumitomo Pharma Co., Ltd. Lurasidone for use in the treatment of memory or learning dysfunction by schizophrenia
TWI329641B (en) * 2005-08-31 2010-09-01 Otsuka Pharma Co Ltd (benzo[b]thiophen-4-yl)piperazine compounds, pharmaceutical compositions comprising the same, uses of the same and processes for preparing the same
JP4785881B2 (ja) * 2007-02-27 2011-10-05 大塚製薬株式会社 医薬
US8258139B2 (en) 2010-11-08 2012-09-04 Dainippon Sumitomo Pharma Co., Ltd. Method of treatment for mental disorders
PL395469A1 (pl) 2011-06-29 2013-01-07 Adamed Spólka Z Ograniczona Odpowiedzialnoscia Pochodne indoloamin do leczenia chorób osrodkowego ukladu nerwowego

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2567884B1 (fr) * 1984-07-19 1987-03-06 Roussel Uclaf Nouveaux derives de l'indole, leur preparation, leur application comme medicaments et les compositions les renfermant
GB8830312D0 (en) * 1988-12-28 1989-02-22 Lundbeck & Co As H Heterocyclic compounds
DK148392D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Heterocykliske forbindelser
EP0900792B1 (en) * 1997-09-02 2003-10-29 Duphar International Research B.V Piperazine and piperidine derivatives as 5-HT1A and dopamine D2-receptor (ant)agonists
WO1999055672A2 (en) * 1998-04-29 1999-11-04 American Home Products Corporation Antipsychotic indolyl derivatives

Also Published As

Publication number Publication date
PL355538A1 (en) 2004-05-04
EA200200727A1 (ru) 2002-12-26
AU2352101A (en) 2001-07-16
HUP0203767A3 (en) 2004-06-28
CZ20022489A3 (cs) 2002-10-16
ZA200204969B (en) 2003-09-22
NO20023148D0 (no) 2002-06-28
KR20020063288A (ko) 2002-08-01
NO20023148L (no) 2002-06-28
BR0016955A (pt) 2003-04-29
MXPA02006498A (es) 2002-11-29
IL150336A0 (en) 2002-12-01
NZ519648A (en) 2004-05-28
US20030050307A1 (en) 2003-03-13
EP1246818A1 (en) 2002-10-09
CN1437598A (zh) 2003-08-20
WO2001049680A1 (en) 2001-07-12
IS6434A (is) 2002-06-19
JP2003519226A (ja) 2003-06-17
HUP0203767A2 (hu) 2003-03-28
AR027134A1 (es) 2003-03-12
SK9452002A3 (en) 2002-11-06
BG106937A (en) 2003-04-30
CA2395606A1 (en) 2001-07-12

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