TR199700625T1 - Osteoporoz (kemik erimesi) tedavisinde yararli olan indol türevleri. - Google Patents
Osteoporoz (kemik erimesi) tedavisinde yararli olan indol türevleri.Info
- Publication number
- TR199700625T1 TR199700625T1 TR97/00625T TR9700625T TR199700625T1 TR 199700625 T1 TR199700625 T1 TR 199700625T1 TR 97/00625 T TR97/00625 T TR 97/00625T TR 9700625 T TR9700625 T TR 9700625T TR 199700625 T1 TR199700625 T1 TR 199700625T1
- Authority
- TR
- Turkey
- Prior art keywords
- optionally substituted
- group
- alkyl
- aryl
- formula
- Prior art date
Links
- 206010065687 Bone loss Diseases 0.000 title 1
- 208000001132 Osteoporosis Diseases 0.000 title 1
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 3
- 125000003107 substituted aryl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- -1 hydroxy, amino Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000005017 substituted alkenyl group Chemical group 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
Ra'nin hidrojen alkil veya tercihe göre ikame edilmis aril olan bir R5 grubunu, Rb'nin ise asagidaki formülün a() bir bölümünü temsil ettigi: (formül) bu formül (a)'da, X, alkil grubunun istege göre ikame edebildigi, bir hidroksi veya bir alkoksi grubunu, veya R5 ve Rt'nin ayri ayri bagimsiz olarak hidrojeni alkili, ikameli alkili, tercihe göre ikameli alkenili, tercihe göre ikameli arili, tercihe göre ikameli arilalkili, tercihe göre ikameli bir heterosiklik grubu veya tercihe göre ikameli bir heterosiklialkil grubunu temsil ettigi veya R5 ile Rt'nin birlikte bir heterosiklik grup olusturdugu bir NR5Rt grubunu; R1 bir alkil veya ikameli/ikamesiz aril grubunu; ve R2,R3 ve R4'ün her biri bagimsizca hidrojen, alkil, aril veya ikameli arili temsil eder; veya Ra'nin yukaridaki formül (a)'nin bir kismini, ve Rb yukarida tanimlanan R5'i temsil ettigi; R6 ve R7'nin ayri ayri hidrojen, hidroksi, amino, alkoksi, tercihe göre ikameli benziloksi, lakilamin, dialkiamino, halo, ...(devami var).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI950030A IT1272878B (it) | 1995-01-10 | 1995-01-10 | Composti indolici |
ITMI951687 IT1307328B1 (it) | 1995-08-01 | 1995-08-01 | Composti indolici |
Publications (1)
Publication Number | Publication Date |
---|---|
TR199700625T1 true TR199700625T1 (tr) | 1998-02-21 |
Family
ID=26331230
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR97/00625T TR199700625T1 (tr) | 1995-01-10 | 1996-01-08 | Osteoporoz (kemik erimesi) tedavisinde yararli olan indol türevleri. |
Country Status (19)
Country | Link |
---|---|
US (1) | US5981525A (tr) |
EP (1) | EP0802902A1 (tr) |
JP (1) | JPH10512251A (tr) |
KR (1) | KR19980701330A (tr) |
AP (1) | AP648A (tr) |
AU (1) | AU4536096A (tr) |
BG (1) | BG101769A (tr) |
BR (1) | BR9606743A (tr) |
CA (1) | CA2209936A1 (tr) |
CZ (1) | CZ217697A3 (tr) |
EA (1) | EA199700098A1 (tr) |
FI (1) | FI972919A (tr) |
HU (1) | HUP9901096A3 (tr) |
NO (1) | NO973178L (tr) |
OA (1) | OA10611A (tr) |
PL (1) | PL321263A1 (tr) |
SK (1) | SK93297A3 (tr) |
TR (1) | TR199700625T1 (tr) |
WO (1) | WO1996021644A1 (tr) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5977125A (en) * | 1994-10-31 | 1999-11-02 | Eisai Co., Ltd. | Mono-or polyenic carboxylic acid derivatives |
GB9614366D0 (en) * | 1996-07-09 | 1996-09-04 | Smithkline Beecham Spa | Novel compounds |
PL330994A1 (en) * | 1996-07-09 | 1999-06-21 | Smithkline Beecham Spa | Indolic derivatives for use in treating osteoporosis |
GB9614347D0 (en) * | 1996-07-09 | 1996-09-04 | Smithkline Beecham Spa | Novel compounds |
GB9703109D0 (en) * | 1997-02-14 | 1997-04-02 | Smith & Nephew | Compositions |
AU6229698A (en) * | 1997-02-21 | 1998-09-09 | Takeda Chemical Industries Ltd. | Fused ring compounds, process for producing the same and use thereof |
WO1998039344A1 (en) | 1997-03-07 | 1998-09-11 | Metabasis Therapeutics, Inc. | Novel purine inhibitors of fructose-1,6-bisphosphatase |
AU6691798A (en) * | 1997-03-07 | 1998-09-22 | Metabasis Therapeutics, Inc. | Novel indole and azaindole inhibitors of fructose-1,6-bisphosphatase |
WO1999033822A1 (en) * | 1997-12-24 | 1999-07-08 | Smithkline Beecham Laboratoires Pharmaceutiques | Indole derivatives useful a.o. for the treatment of osteoporosis |
US6506758B2 (en) | 1997-12-24 | 2003-01-14 | Smithkline Beecham Laboratoires Pharmceutiques | Indole derivatives useful A.O. for the treatment of osteoporosis |
US6861448B2 (en) * | 1998-01-14 | 2005-03-01 | Virtual Drug Development, Inc. | NAD synthetase inhibitors and uses thereof |
WO1999036422A1 (en) | 1998-01-14 | 1999-07-22 | The Uab Research Foundation | Methods of synthesizing and screening inhibitors of bacterial nad synthetase enzyme, compounds thereof, and methods of treating bacterial and microbial infections with inhibitors of bacterial nad synthetase enzyme |
US6673827B1 (en) | 1999-06-29 | 2004-01-06 | The Uab Research Foundation | Methods of treating fungal infections with inhibitors of NAD synthetase enzyme |
GB9914371D0 (en) * | 1999-06-18 | 1999-08-18 | Smithkline Beecham Plc | Novel compounds |
SE9903760D0 (sv) | 1999-10-18 | 1999-10-18 | Astra Ab | New compounds |
SE9904176D0 (sv) * | 1999-11-18 | 1999-11-18 | Astra Ab | New use |
AU2002254616B2 (en) * | 2001-04-11 | 2007-09-06 | Idenix (Cayman) Limited | Phenylindoles for the treatment of HIV |
JP2005510482A (ja) * | 2001-10-16 | 2005-04-21 | アストラゼネカ・アクチエボラーグ | 線維筋痛症候群の治療方法 |
WO2004014364A1 (en) * | 2002-08-07 | 2004-02-19 | Idenix (Cayman) Limited | Substituted phenylindoles for the treatment of hiv |
ITMI20040875A1 (it) * | 2004-04-30 | 2004-07-30 | Ist Naz Stud Cura Dei Tumori | Derivati indolici utili per il trattamento della resistenza agli agenti antitumorali |
DE602005023360D1 (de) | 2004-09-17 | 2010-10-14 | Idenix Pharmaceuticals Inc | Phosphoindole als HIV-Inhibitoren |
EP1861394A1 (en) * | 2005-03-03 | 2007-12-05 | H.Lundbeck A/S | Substituted pyridine derivatives |
NZ575831A (en) * | 2006-09-29 | 2011-12-22 | Idenix Pharmaceuticals Inc | Enantiomerically pure phosphoindoles as hiv inhibitors |
LU91725B1 (en) | 2010-09-02 | 2012-03-05 | Ct De Rech Public De La Sante | Novel uses of V-ATPASE inhibitors |
US9115128B2 (en) * | 2013-06-06 | 2015-08-25 | Anthem Biosciences Pvt. Ltd. | Compounds of 3-(5-substituted Oxy-2, 4-dinitrophenyl)-2-oxo-propionic acid ester, synthesis and applications thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0449496B1 (en) * | 1990-03-20 | 1994-07-20 | Sharp Kabushiki Kaisha | Method for mounting a semiconductor device |
CA2038925A1 (en) * | 1990-03-26 | 1991-09-27 | Takashi Sohda | Indole derivatives, their production and use |
US5312928A (en) * | 1991-02-11 | 1994-05-17 | Cambridge Neuroscience | Calcium channel antagonists and methodology for their identification |
-
1996
- 1996-01-08 AU AU45360/96A patent/AU4536096A/en not_active Abandoned
- 1996-01-08 JP JP8521450A patent/JPH10512251A/ja active Pending
- 1996-01-08 CA CA002209936A patent/CA2209936A1/en not_active Abandoned
- 1996-01-08 KR KR1019970704719A patent/KR19980701330A/ko not_active Application Discontinuation
- 1996-01-08 PL PL96321263A patent/PL321263A1/xx unknown
- 1996-01-08 CZ CZ972176A patent/CZ217697A3/cs unknown
- 1996-01-08 EP EP96901275A patent/EP0802902A1/en not_active Withdrawn
- 1996-01-08 US US08/860,760 patent/US5981525A/en not_active Expired - Fee Related
- 1996-01-08 WO PCT/EP1996/000157 patent/WO1996021644A1/en not_active Application Discontinuation
- 1996-01-08 AP APAP/P/1997/001029A patent/AP648A/en active
- 1996-01-08 BR BR9606743A patent/BR9606743A/pt unknown
- 1996-01-08 SK SK932-97A patent/SK93297A3/sk unknown
- 1996-01-08 HU HU9901096A patent/HUP9901096A3/hu unknown
- 1996-01-08 TR TR97/00625T patent/TR199700625T1/tr unknown
-
1997
- 1997-07-07 BG BG101769A patent/BG101769A/xx unknown
- 1997-07-09 FI FI972919A patent/FI972919A/fi unknown
- 1997-07-09 OA OA70046A patent/OA10611A/en unknown
- 1997-07-09 NO NO973178A patent/NO973178L/no unknown
- 1997-08-08 EA EA199700098A patent/EA199700098A1/ru unknown
Also Published As
Publication number | Publication date |
---|---|
MX9705243A (es) | 1997-10-31 |
AP9701029A0 (en) | 1997-07-31 |
FI972919A (fi) | 1997-09-09 |
NO973178L (no) | 1997-09-09 |
US5981525A (en) | 1999-11-09 |
BG101769A (en) | 1998-04-30 |
AU4536096A (en) | 1996-07-31 |
NO973178D0 (no) | 1997-07-09 |
EA199700098A1 (ru) | 1997-12-30 |
JPH10512251A (ja) | 1998-11-24 |
OA10611A (en) | 2002-09-03 |
CA2209936A1 (en) | 1996-07-18 |
HUP9901096A3 (en) | 2000-12-28 |
HUP9901096A2 (hu) | 1999-07-28 |
CZ217697A3 (cs) | 1998-03-18 |
KR19980701330A (ko) | 1998-05-15 |
EP0802902A1 (en) | 1997-10-29 |
SK93297A3 (en) | 1998-02-04 |
BR9606743A (pt) | 1997-12-30 |
AP648A (en) | 1998-05-25 |
WO1996021644A1 (en) | 1996-07-18 |
PL321263A1 (en) | 1997-11-24 |
FI972919A0 (fi) | 1997-07-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TR199700625T1 (tr) | Osteoporoz (kemik erimesi) tedavisinde yararli olan indol türevleri. | |
NO921287L (no) | Nytt bindeledd for bioaktive midler | |
TR199901653T2 (tr) | Fitalazinonlar. | |
DK0682663T3 (da) | 4-Hydroxybenzopyran-2-oner og 4-hydroxycycloalkyl[b]pyran-2-oner, der er nyttige til behandling af retrovirale infektioner | |
NZ507735A (en) | Indole derivatives useful for treating malignant and other diseases caused by pathological cell proliferation | |
TR199902357T2 (tr) | Yeni bilesimler. | |
TR200002482T2 (tr) | 6,9-Diikameli 2-(Trans-(4-Aminosiklohekzil) Amino)Pürinler | |
DE69818042D1 (de) | Flüssige benzisochinoline derivate | |
ES2012646A6 (es) | Un procedimiento para la preparacion de derivados de piridazinona. | |
PT918776E (pt) | Sintese total de acilfulvenos antitumorais | |
PT91575A (pt) | Procede de preparation de benzylamines disubstituees utiles comme medicaments | |
IT1315267B1 (it) | Derivati di 2-(1h-indol-3-il)-2-oxo-acetammidi ad attivita'antitumorale | |
TR200200125T2 (tr) | Yeni aminotiyazol türevleri, bunların hazırlanması ve bunları içeren farmasötik kompozisyonlar. | |
TR200000227T2 (tr) | Piperazin içeren reaktif boyalar. | |
ATE262509T1 (de) | Indolinderivate als lichtschutzmittel | |
TR200001992T2 (tr) | Osteoporoz tedavisinde de yararlı olan indol türevleri. | |
MX9701949A (es) | Derivados de distamicina substituidos con bis-(2-haloetil) aminofenilo como agentes antitumorales y antivirales. | |
AU2713897A (en) | Antiviral 2,4-pyrimidinedione derivatives and process for the preparation thereof | |
TR199902873T2 (tr) | Miyozun modülasyonu için 17 -aliloksi(tiyo)alkil-androstan türevleri. | |
ES2152563T3 (es) | Procedimiento para preparar derivados de dihidroxipirimidina. | |
TR200201689T2 (tr) | Yeni indol türevleri | |
TR199800110T1 (tr) | Azotiofenler. | |
TR200100133T2 (tr) | FKBP İnhibitörleri | |
IL123080A0 (en) | Carbamoylcarboxamides their preparation and use | |
TR200002485T2 (tr) | N-Sülfonil ve N-Sülfinil Fenilglisinamid |